Results 41 to 50 of about 111,283 (329)

MT1-MMP sheds LYVE-1 on lymphatic endothelial cells and suppresses VEGF-C production to inhibit lymphangiogenesis [PDF]

, 2016
Lymphangiogensis is involved in various pathological conditions, such as arthritis and cancer metastasis. Although many factors have been identified to stimulate lymphatic vessel growth, little is known about lymphangiogenesis inhibitors.
Cao, R, Cao, Y, Jin, G, Wong, HLX, Zhang, S, Zhou, Z   +5 more
core   +1 more source

Lymphatic Endothelial Differentiation in Pulmonary Lymphangioleiomyomatosis Cells [PDF]

Journal of Histochemistry & Cytochemistry, 2013
Pulmonary lymphangioleiomyomatosis (LAM) is a rare, low-grade neoplasm affecting almost exclusively women of childbearing age. LAM belongs to the family of perivascular epithelioid cell tumors, characterized by spindle and epithelioid cells with smooth muscle and melanocytic differentiation.
Jennifer M, Davis, Elizabeth, Hyjek, Aliya N, Husain, Le, Shen, Jennifer, Jones, Lucia A, Schuger   +5 more
openaire   +2 more sources

Podoplanin immunopositive lymphatic vessels at the implant interface in a rat model of osteoporotic fractures [PDF]

, 2013
Insertion of bone substitution materials accelerates healing of osteoporotic fractures. Biodegradable materials are preferred for application in osteoporotic patients to avoid a second surgery for implant replacement. Degraded implant fragments are often
Alt, Volker, Gelinsky, Michael, Hanke, Thomas, Hartmann, Sonja, Heinemann, Sascha, Heiss, Christian, Kampschulte, Marian, Kauschke, Vivien, Kautz, Armin R., Kilian, Olaf, Langheinrich, Alexander, Lips, Katrin Susanne, Ray, Seemun, Schnabelrauch, Matthias, Schnettler, Reinhard, Schumacher, Matthias, Thormann, Ulrich   +16 more
core   +8 more sources

An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo. [PDF]

PLoS ONE, 2013
Afadin is an intracellular binding partner of nectins, cell-cell adhesion molecules, and plays important roles in the formation of cell-cell junctions. Afadin-knockout mice show early embryonic lethality, therefore little is known about the function of ...
Takashi Majima, Keisuke Takeuchi, Keigo Sano, Masanori Hirashima, Dimitar P Zankov, Miki Tanaka-Okamoto, Hiroyoshi Ishizaki, Jun Miyoshi, Hisakazu Ogita   +8 more
doaj   +1 more source

Lymphatic endothelium stimulates melanoma metastasis and invasion via MMP14-dependent Notch3 and b1-integrin activation [PDF]

, 2018
Lymphatic invasion and lymph node metastasis correlate with poor clinical outcome in melanoma. However, the mechanisms of lymphatic dissemination in distant metastasis remain incompletely understood.
Alve, S, Balistreri, G, Gramolelli, S, Hautaniemi, S, Icay, K, Ivaska, J, Lehti, K, Niiranen, O, Ojala, PM, Paatero, I, Pekkonen, P, Perälä, N, Repo, P, Saharinen, P, Taiwo, A, Tatti-Bugaeva, O, Tuohinto, K, Zinovkina, N   +17 more
core   +1 more source

Intestinal Lymphatic Endothelial Cells Produce R-Spondin3 [PDF]

Scientific Reports, 2018
AbstractThe R-Spondin (R-Spo) family regulates WNT signaling and stimulates the proliferation and differentiation of intestinal stem cells (ISCs). R-Spo plays a critical role in maintaining intestinal homeostasis, but endogenous producers of R-Spo in the intestine remain to be investigated.
Reiki Ogasawara, Daigo Hashimoto, Shunsuke Kimura, Eiko Hayase, Takahide Ara, Shuichiro Takahashi, Hiroyuki Ohigashi, Kosuke Yoshioka, Takahiro Tateno, Emi Yokoyama, Ko Ebata, Takeshi Kondo, Junichi Sugita, Masahiro Onozawa, Toshihiko Iwanaga, Takanori Teshima   +15 more
openaire   +3 more sources

Slit2/Robo4 signaling modulates HIV-1 gp120-induced lymphatic hyperpermeability. [PDF]

PLoS Pathogens, 2012
Dissemination of HIV in the host involves transit of the virus and virus-infected cells across the lymphatic endothelium. HIV may alter lymphatic endothelial permeability to foster dissemination, but the mechanism is largely unexplored.
Xuefeng Zhang, Jinlong Yu, Paula M Kuzontkoski, Weiquan Zhu, Dean Y Li, Jerome E Groopman   +5 more
doaj   +1 more source

Bone Morphogenetic Protein 9 Regulates Early Lymphatic-Specified Endothelial Cell Expansion during Mouse Embryonic Stem Cell Differentiation

Stem Cell Reports, 2019
Summary: Exogenous cues involved in the regulation of the initial steps of lymphatic endothelial development remain largely unknown. We have used an in vitro model based on the co-culture of vascular precursors derived from mouse embryonic stem cell (ESC)
Mariela Subileau, Galina Merdzhanova, Delphine Ciais, Véronique Collin-Faure, Jean-Jacques Feige, Sabine Bailly, Daniel Vittet   +6 more
doaj   +1 more source

Homeobox genes in normal and abnormal vasculogenesis [PDF]

, 2008
Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with ...
Cantile M, CILLO, CLEMENTE, Schiavo G, Terracciano L   +3 more
core   +1 more source

Endothelial cell plasticity: how to become and remain a lymphatic endothelial cell [PDF]

Development, 2010
Lineage commitment and differentiation into mature cell types are mostly considered to be unidirectional and irreversible processes. However, recent results have challenged this by showing that terminally differentiated cell types can be reprogrammed into other cell types, an important step towards devising strategies for gene therapy and tissue ...
Guillermo, Oliver, R Sathish, Srinivasan
openaire   +2 more sources