Nestin as a Marker Beyond Angiogenesis—Expression Pattern in Haemangiomas and Lymphangiomas [PDF]
Background: The intermediate filament nestin was first described in stem and progenitor cells of neural and mesenchymal origin. Additionally, it is expressed in endothelial cells during wound healing and tumorigenesis.
Andreas Mamilos+11 more
doaj +2 more sources
Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition
Central conducting lymphatic anomaly (CCLA) due to congenital maldevelopment of the lymphatics can result in debilitating and life-threatening disease with limited treatment options.
Sarah E. Sheppard+32 more
doaj +2 more sources
The lymphatic microvasculature is uniquely adapted for the continuous removal of interstitial fluid and proteins, and is an important point of entry for leukocytes and tumor cells. The traditional view that lymphatic capillaries are passive participants in these tasks is currently being challenged.
Michael S. Pepper, Mihaela Skobe
openalex +4 more sources
DeepCAGE Transcriptomics Reveal an Important Role of the Transcription Factor MAFB in the Lymphatic Endothelium [PDF]
Lothar C. Dieterich+18 more
openalex +2 more sources
Dynamic cytoskeletal regulation of cell shape supports resilience of lymphatic endothelium. [PDF]
Schoofs H+21 more
europepmc +2 more sources
Evidence Supporting a Lymphatic Endothelium Origin for Angiomyolipoma, a TSC2(-) Tumor Related to Lymphangioleiomyomatosis. [PDF]
Yue M+6 more
europepmc +2 more sources
Dermal DC mobilization requires docking to CCL21 on lymphatic ...
Orna Tal+7 more
openalex +2 more sources
CD44 Binds to Macrophage Mannose Receptor on Lymphatic Endothelium and Supports Lymphocyte Migration via Afferent Lymphatics [PDF]
Marko Salmi+4 more
openalex +2 more sources
MicroRNAs secreted by the parasitic nematode Brugia malayi disrupt lymphatic endothelial cell integrity. [PDF]
Lymphatic filariasis (LF) is a neglected tropical disease affecting over 51 million people in 72 endemic countries. Causative agents of LF are mosquito-borne parasitic nematodes Wuchereria bancrofti, Brugia malayi, and Brugia timori.
Hailey Johnson+4 more
doaj +2 more sources
Gap junction coupling is required for tumor cell migration through lymphatic endothelium. [PDF]
Karpinich NO, Caron KM.
europepmc +2 more sources