Results 1 to 10 of about 575,168 (180)

HSF1 facilitates the multistep process of lymphatic metastasis in bladder cancer via a novel PRMT5‐WDR5‐dependent transcriptional program

open access: yesCancer Communications, 2022
Background Lymphatic metastasis has been associated with poor prognosis in bladder cancer patients with limited therapeutic options. Emerging evidence shows that heat shock factor 1 (HSF1) drives diversified transcriptome to promote tumor growth and ...
Ming Huang   +16 more
doaj   +2 more sources

Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration

open access: yesFrontiers in Oncology, 2022
ObjectiveSince there are few studies exploring genes associated with lymphatic metastasis of thyroid carcinoma (THCA), this study was conducted to explore genes associated with lymphatic metastasis of THCA and to investigate the relationship with immune ...
Linfeng Wu   +14 more
doaj   +2 more sources

Bacterial Lymphatic Metastasis in Infection and Immunity [PDF]

open access: yesCells, 2021
Lymphatic vessels permeate tissues around the body, returning fluid from interstitial spaces back to the blood after passage through the lymph nodes, which are important sites for adaptive responses to all types of pathogens.
Matthew K Siggins, S. Sriskandan
semanticscholar   +6 more sources

Long Non-Coding RNA MAPK8IP1P2 Inhibits Lymphatic Metastasis of Thyroid Cancer by Activating Hippo Signaling via Sponging miR-146b-3p

open access: yesFrontiers in Oncology, 2021
The principal issue derived from thyroid cancer is its high propensity to metastasize to the lymph node. Aberrant exprssion of long non-coding RNAs have been extensively reported to be significantly correlated with lymphatic metastasis of thyroid cancer.
Xiaoli Liu   +12 more
doaj   +2 more sources

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer

open access: yesCell Death and Disease, 2023
Lymphatic metastasis is the most common pattern of bladder cancer (BCa) metastasis and has an extremely poor prognosis. Emerging evidence shows that ubiquitination plays crucial roles in various processes of tumors, including tumorigenesis and ...
Kanghua Xiao   +10 more
doaj   +2 more sources

Progression of Metastasis through Lymphatic System [PDF]

open access: yesCells, 2021
Lymph nodes are the most common sites of metastasis in cancer patients. Nodal disease status provides great prognostic power, but how lymph node metastases should be treated is under debate.
Hengbo Zhou, Pin-Ji Lei, T. Padera
semanticscholar   +4 more sources

RAF1 promotes lymphatic metastasis of hypopharyngeal carcinoma via regulating LAGE1: an experimental research

open access: yesJournal of Translational Medicine, 2022
Background Lymphatic metastasis was an independent prognostic risk factor for hypopharyngeal carcinoma and was the main cause of treatment failure. The purpose of this study was to screen the differential genes and investigate the mechanism of lymphatic ...
Yanshi Li   +6 more
doaj   +2 more sources

Tumor metastasis and the lymphatic vasculature [PDF]

open access: bronzeInternational Journal of Cancer, 2009
AbstractTumor‐associated lymphatic vessels act as a conduit by which disseminating tumor cells access regional lymph nodes and form metastases there. Lymph node metastasis is of major prognostic significance for many types of cancer, although lymph node metastases are themselves rarely life‐threatening.
Jonathan P. Sleeman, Wilko Thiele
openalex   +5 more sources

BACH1-induced ferroptosis drives lymphatic metastasis by repressing the biosynthesis of monounsaturated fatty acids

open access: yesCell Death and Disease, 2023
Esophageal squamous cell carcinoma (ESCC) is one of the fatal malignancies worldwide. It has an increased propensity to metastasize via lymphogenous routes in an early stage.
Xiufeng Xie   +10 more
doaj   +2 more sources

Potential therapeutic strategies for lymphatic metastasis [PDF]

open access: greenMicrovascular Research, 2007
Physiologically, the lymphatic system regulates fluid volume in the interstitium and provides a conduit for immune cells to travel to lymph nodes, but pathologically, the lymphatic system serves as a primary escape route for cancer cells. Lymphatic capillaries have a thin discontinuous basement membrane, lack pericyte coverage and often contain ...
Bernadette Zwaans, Diane R. Bielenberg
openalex   +4 more sources

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