Results 21 to 30 of about 575,621 (304)

Patterns of lymph node metastasis in level IIB and contralateral level VI for papillary thyroid carcinoma with pN1b and safety of low collar extended incision for neck dissection in level II

World Journal of Surgical Oncology, 2023
Objective To explore relevant clinical factors of level IIB and contralateral level VI lymph node metastasis and evaluate the safety of low-collar extended incision (LCEI) for lymph node dissection in level II for papillary thyroid carcinoma (PTC) with ...
Yudong Ning, Yuebai Liu, Dingfen Zeng, Yuqiu Zhou, Linjie Ma, Shuang Dong, Jianfeng Sheng, Gaosong Wu, Wen Tian, Yongcong Cai, Chao Li   +10 more
doaj   +1 more source

Cancer-associated fibroblast-derived PAI-1 promotes lymphatic metastasis via the induction of EndoMT in lymphatic endothelial cells

Journal of experimental & clinical cancer research : CR, 2023
Background Endothelial-mesenchymal transition (EndoMT) is an emerging adaptive process that modulates lymphatic endothelial function to drive aberrant lymphatic vascularization in the tumour microenvironment (TME); however, the molecular determinants ...
Wenfei Wei, Hui-Ling Zhou, Pei Chen, Xiaodi Huang, Long Huang, Luojiao Liang, Chu-Hong Guo, Chenfei Zhou, Lan Yu, Liangsheng Fan, Wen Wang   +10 more
semanticscholar   +1 more source

Association of MACC1 expression with lymphatic metastasis in colorectal cancer: A nested case-control study.

PLoS ONE, 2021
MACC1 gene is a newly discovered gene and plays an important role in the metastasis of colorectal cancer (CRC). The objective of this study was to investigate whether MACC1 is an independent factor associated with lymphatic metastasis in CRC patients. We
Zheying Zhang, Huijie Jia, Yuhang Wang, Baoshun Du, Jiateng Zhong   +4 more
doaj   +1 more source

Multifunctional Gold Nanoclusters for Effective Targeting, Near-Infrared Fluorescence Imaging, Diagnosis, and Treatment of Cancer Lymphatic Metastasis

ACS Nano, 2022
Developing effective lymph-node (LN) targeting and imaging probes is crucial for the early detection and diagnosis of tumor metastasis to improve patient survival. Most current clinical LN imaging probes are based on small organic dyes (e.g., indocyanine
Zeyang Pang, Weixiao Yan, Jie Yang, Qizhen Li, Yuan Guo, Dejian Zhou, Xingyu Jiang   +6 more
semanticscholar   +1 more source

Lymphatic metastasis due to glioblastoma [PDF]

Neurosciences, 2016
Glioblastomas are the most common malignant primary brain tumor. Only 0.2%-0.5% of cases metastasise outside the brain.[1][1],[2][2] We present a rare case of glioblastoma with bilateral cervical lymph node metastases.
Husam Wassati, Suat W. Loo, Hu Liang Low
openaire   +3 more sources

RNA N6-methyladenosine reader IGF2BP2 promotes lymphatic metastasis and epithelial-mesenchymal transition of head and neck squamous carcinoma cells via stabilizing slug mRNA in an m6A-dependent manner

Journal of experimental & clinical cancer research : CR, 2021
Lymph node metastasis is the main cause of poor prognosis of head and neck squamous carcinoma (HNSCC) patients. N6-methyladenosine (m6A) RNA modification is an emerging epigenetic regulatory mechanism for gene expression, and as a novel m6A reader ...
Dan Yu, Min Pan, Yanshi Li, T. Lu, Zhihai Wang, Chuan Liu, G. Hu   +6 more
semanticscholar   +1 more source

Paclitaxel treatment enhances lymphatic metastasis of B16F10 melanoma cells via CCL21/CCR7 axis

International Journal on Biological Sciences, 2022
Chemotherapeutic drugs have been successfully used to treat several cancers, including melanoma. However, metastasis occasionally occurs after chemotherapy.
Li Zhang, Linyu Zhu, Xiaohan Yao, Xiaohan Lou, Jiajia Wan, Xixi Duan, L. Pan, Anqi Li, Zhuoyu Gu, Ming Wang, Fazhan Wang, Zhihai Qin   +11 more
semanticscholar   +1 more source

Tumor‐derived exosomal BCYRN1 activates WNT5A/VEGF‐C/VEGFR3 feedforward loop to drive lymphatic metastasis of bladder cancer

Clinical and Translational Medicine, 2021
Background Patients with lymph node (LN) metastatic bladder cancer (BCa) present with extremely poor prognosis. BCa‐derived exosomes function as crucial bioactive cargo carriers to mediate the signal transduction in tumor microenvironment triggering ...
Hanhao Zheng, Changhao Chen, Yuming Luo, Min Yu, Wang He, M. An, Bowen Gao, Yao Kong, Yiyao Ya, Yan Lin, Yuting Li, K. Xie, Jian Huang, Tianxin Lin   +13 more
semanticscholar   +1 more source

The characteristics of isolated para-aortic lymph node metastases in endometrial cancer and their prognostic significance

Therapeutic Advances in Medical Oncology, 2020
Background: The aim of this study was to clarify the features and prognostic significance of isolated para-aortic lymphatic metastasis of endometrial cancer.
Jianbin Guo, Haili Qian, Fei Ma, Ying Zhang, Xiujuan Cui, Hua Duan   +5 more
doaj   +1 more source

IFN-γ–dependent tumor-antigen cross-presentation by lymphatic endothelial cells promotes their killing by T cells and inhibits metastasis

Science Advances, 2022
Tumor-associated lymphatic vessels promote metastasis and regulate antitumor immune responses. Here, we assessed the impact of cytotoxic T cells on the local lymphatic vasculature and concomitant tumor dissemination during an antitumor response ...
L. Garnier, R. Pick, J. Montorfani, Mengzhu Sun, D. Brighouse, Nicolas Liaudet, T. Kammertoens, T. Blankenstein, Nicolas Page, Jeremiah Bernier-Latamani, Ngoc Lan Tran, T. Petrova, D. Merkler, C. Scheiermann, S. Hugues   +14 more
semanticscholar   +1 more source