Results 31 to 40 of about 1,898 (50)

Advances in Drugs Targeting Lymphangiogenesis for Preventing Tumor Progression and Metastasis

Frontiers in Oncology, 2022
Metastasis of cancer cells from the primary tumor to other organs and tissues in the body is the leading cause of death in patients with malignancies. One of the principal ways cancer cells travel is through lymphatic vessels, and tumor invasion into the
Chuqi Wang, Chuqi Wang, Ming Chu
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LNMAC Promotes Cervical Squamous Cell Carcinoma Lymphatic Metastasis via Epigenetic Regulation of FGF2‐Induced Lymphangiogenesis

Advanced Science
The lymph node is the most common site of distant metastasis of cervical squamous cell carcinoma (CSCC), which elicits dismal prognosis and limited efficiency for treatment. Elucidation of the mechanisms underlying CSCC lymphatic metastasis would provide
Chunyu Zhang, Li Yuan, Weijia Wen, Caixia Shao, Yuandong Liao, Yan Jia, Xueyuan Zhao, Yan Liao, Dingze Xu, Linna Chen, Guofen Yang, Hongye Jiang, Wei Wang, Shuzhong Yao   +13 more
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Progress in the Mechanism of Lymphangiogenesis and Lymphatic Metastasis 
of Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2021
Lung cancer ranks the first cancer-related morbidity and mortality in China. Tumor metastasis always predicts the poor prognosis for patients. Moreover, lymphatic metastasis is one of the most significant predictors of poor prognosis in patients with non-
Xiayao DIAO, Chao GUO, Shanqing LI
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Analysis of lymph nodes metastasis in hypopharyngeal squamous cell carcinoma based on contrast‐enhanced computed tomography imaging

Precision Radiation Oncology, 2021
Objective To investigate the frequency, distribution, and potential factors of lymphatic metastasis at each nodal level, and stratify the risk of lymph node metastasis in hypopharyngeal squamous cell carcinoma based on computed tomography.
Dongqing Wang, Shuguang Zhang, Jin Xu, Limin Zhai, Baosheng Li   +4 more
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Cutaneous metastasis of bladder urothelial carcinoma; A rare conditions

Urology Case Reports, 2022
Cutaneous is an extremely rare metastatic area of bladder urothelial carcinoma. Pure cutaneous metastasis without systemic metastasis is very rare and less than ten cases have been reported in the literature. Our patient had various lymphatic fistulas to
Hakan Öztürk, Selin Yurtsever, Arzum Özer, Çağatay Arslan, Fatma Seher Pehlivan, Aysun Tekeli   +5 more
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Integrin α6‐containing extracellular vesicles promote lymphatic remodelling for pre‐metastatic niche formation in lymph nodes via interplay with CD151

Journal of Extracellular Vesicles
Heterogeneous extracellular vesicles (EVs) from various types of tumours are acknowledged for inducing the formation of pre‐metastatic “niches” in draining lymph nodes (LNs) to promote lymphatic metastasis.
Yan Lin, Hanhao Zheng, Linpei Jia, Yuming Luo, Dingwen Zhang, Mingjie An, Mingrui Pang, Xiayao Diao, Wenjie Li, Jiancheng Chen, Yuanlong Li, Daiyin Liu, Zhicong Liu, Jian Huang, Tianxin Lin, Changhao Chen   +15 more
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Chitinase 3‐like 1 expression associated with lymphatic metastasis and prognosis in urothelial carcinoma of the bladder

Clinical & Translational Immunology
Objectives Lymphatic metastasis, an early stage of the metastasis process, is associated with adverse clinical outcomes in urothelial carcinoma of the bladder (UCB).
Bo Wang, Ke Chen, Mingchao Gao, Xi Sun, Wang He, Junyu Chen, Wenjuan Yang, Tenghao Yang, Haide Qin, Honglian Ruan, Hao Huang, Tianxin Lin, Jian Huang   +12 more
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Risk factors for lymphatic and hematogenous metastasis after diagnosis of cutaneous Melanoma in Taiwan

Journal of the Formosan Medical Association, 2022
Background: Risk factors of lymphatic and hematogenous metastasis in cutaneous melanoma remained unclear in Asian population. This study aimed to identify clinical and histopathological factors to predict metastatic pathways in cutaneous melanoma in ...
Che-Chia Hsu, Tung-Lin Lee, Ming-Hsien Lin, Yi-Hua Liao, Jau-Yu Liau, Yi-Shuan Sheen   +5 more
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Recent advances in lymphatic targeted drug delivery system for tumor metastasis

Cancer Biology & Medicine, 2014
The lymphatic system has an important defensive role in the human body. The metastasis of most tumors initially spreads through the surrounding lymphatic tissue and eventually forms lymphatic metastatic tumors; the tumor cells may even transfer to other ...
Xiao-Yu Zhang, Wei-Yue Lu
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The role of VEGF-C/D and Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma

Journal of Experimental & Clinical Cancer Research, 2009
Background To investigate the role of vascular endothelial growth factors (VEGF)-C/D and their receptor Flt-4 in the lymphatic metastasis of early-stage invasive cervical carcinoma.
Zhang Renhua, Zhang Shiqian, Yu Hao, Zhang Linlin   +3 more
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