Results 81 to 90 of about 1,203,096 (351)

Impaired meningeal lymphatic drainage in Listeria monocytogenes infection

Frontiers in Immunology
Previous studies have demonstrated an association between lymphatic vessels and diseases caused by bacterial infections. Listeria monocytogenes (LM) bacterial infection can affect multiple organs, including the intestine, brain, liver and spleen, which ...
Jian Feng, Yuanzhen Ren, Xilin Wang, Xilin Wang, Xiaojing Li, Xingguo Zhu, Baokai Zhang, Baokai Zhang, Qi Zhao, Xiaochen Sun, Xinxin Tian, Hongyang Liu, Fan Dong, Xiu-Li Li, Linlin Qi, Bin Wei, Bin Wei   +16 more
doaj   +1 more source

Mouse Brain Lymphatic Vessels

ACS Chemical Neuroscience
Abstract The lymphatic system plays a vital role in immune function and waste removal, yet its involvement in the brain has remained largely unexplored. This study provides compelling evidence of lymphatic vessels in the mouse brain, specifically in the cortex, thalamus, and hippocampus.
Amin Tamadon, Alireza Afshar, Nadiar M. Mussin, Kulyash R. Zhilisbayeva, Madina A. Kurmanalina, Akmaral Baspakova, Raisa A. Aringazina, Mahdi Mahdipour, Nader Tanideh, Arezoo Khoradmehr, Mostafa Najarasl, Payam Taheri   +11 more
openaire   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

The role of lymphatics in renal inflammation [PDF]

, 2017
Progressive renal diseases are characterized by tubulointerstitial inflammatory cell recruitment, tubular atrophy and fibrosis. Various aspects of the recruitment of leukocytes have been extensively studied, but the exit routes (i.e.
Bonani, Marco, Seeger, Harald, Segerer, Stephan   +2 more
core  

Neurotrophic keratitis in a patient with disseminated lymphangiomatosis. [PDF]

, 2009
INTRODUCTION: Neurotrophic keratitis, a degenerative corneal disease caused by trigeminal nerve impairment, has many etiologies and remains very difficult to treat.
Charukamnoetkanok, Puwat, Knickelbein, Jared E, Stefko, Susan T   +2 more
core   +2 more sources

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Lymphatic vessel density and VEGF-C expression are significantly different among benign and malignant thyroid lesions [PDF]

, 2010
Thyroid cancer is the most frequent endocrine neoplasia worldwide. The route for metastasis and loco-regional invasion preferentially occurs by lymphatic vessels.
A Longatto-Filho, A Longatto-Filho, Adhemar Longatto-Filho, Alda Wakamatsu, AM Byrne, BHH Lang, Eduardo Anselmo Garcia, GNL Torre, H Kurahara, HJ Kahn, I Auwera Van der, J Afonso, JS Reis-Fillho, K Alitalo, Kleber Simões, L Jussila, M Fassnacht, MJ Karkkainen, MJ Schlumberger, N Weidner, NJ Beasley, P Bono, RJ Roskoski, Roberto Souza Camargo, Rodrigo Albergaria Ressio, RS Camargo, SA Stacker, SE Duff, T Kondo, TA Giorgadze, TP Padera, V Schacht, Venâncio Avancini Ferreira Alves, Y Yamazaki, Z Gombos   +34 more
core   +1 more source

Spleen‐Targeting Biomimetic Hybrid Nanocarriers for Systemic Immune Reprogramming in Colitis: RBC Membrane Vesicle‐Fused Lipid Nanoparticles

Advanced Functional Materials, EarlyView.
A spleen‐targeting hybrid nanoplatform (RBCMV‐LNP‐RP) harnessing erythrophagocytosis mimics senescent red blood cell clearance to achieve spleen‐specific delivery of rapamycin. This biomimetic system enables selective accumulation in splenic macrophages, orchestrating systemic immune reprogramming and promoting mucosal healing in an inflammatory bowel ...
Jun Kwon, Hee Su Sohn, Jong Sang Yoon, So Won Jeon, Hee Gyeong Ko, Min‐Ho Kang, Jisun Lee, Jae‐Hwan Nam, Louis T. Merriam, Edy Y. Kim, Han Young Kim   +10 more
wiley   +1 more source

Enhancement of Lymphatic Vessels in the Superficial Layer in a Rat Model of a Lymphedematous Response

Plastic and Reconstructive Surgery, Global Open, 2018
Background:. The morphologic and histologic behavior of lymphatic vessels in lymphedema has not been well analyzed using laboratory animals. The purpose of the present study was to elucidate the regeneration process of lymphatic vessels after acute ...
Kumiko Matsumoto, MD, Jun Kosaka, MD, DSci, Hiroo Suami, MD, PhD, Yoshihiro Kimata, MD, PhD   +3 more
doaj   +1 more source

DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. [PDF]

, 2015
The small intestine is a dynamic and complex organ that is characterized by constant epithelium turnover and crosstalk among various cell types and the microbiota.
Barker, Benedito, Cansaran Saygili Demir, Christophe Cisarovsky, Freddy Radtke, Humphrey, Jeremiah Bernier-Latmani, Jurisic, Kamba, Malanchi, Marine Bruand, Muriel Jaquet, Nowotschin, Olivier Dormond, Prewett, Rui Benedito, Sanjiv A. Luther, Shutter, Simone Ragusa, Srinivas, Stefanie Siegert, Suzel Davanture, Tatiana V. Petrova, Womack   +23 more
core   +2 more sources