Results 201 to 210 of about 4,183,330 (355)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Utilizing T-Lymphocyte Activation-Related Cytokines to Predict Non-Responsiveness to Treatment in Pediatric Kawasaki Disease. [PDF]

Pediatric Health Med Ther
Ye B, Xiao J, Zhang C.
europepmc   +1 more source

The Role of Protein and Lipid Clustering in Lymphocyte Activation. [PDF]

Front Immunol, 2021
Lamerton RE, Lightfoot A, Nieves DJ, Owen DM.   +3 more
europepmc   +1 more source

Mechanosensing in T lymphocyte activation.

Biophysical Journal, 2012
Edward Judokusumo, Erdem D. Tabdanov, Sudha Kumari, Michael Loran Dustin, L. Kam   +4 more
semanticscholar   +1 more source

Human Immunodeficiency Virus-Specific Circulating CD8 T Lymphocytes Have Down-Modulated CD3ζ and CD28, Key Signaling Molecules for T-Cell Activation

, 2000
Linda A. Trimble, Premlata Shankar, Mark Patterson, Johanna P. Daily, Judy Lieberman   +4 more
openalex   +2 more sources

Vanadate Induces Calcium Signaling, Ca2+ Release-Activated Ca2+ Channel Activation, and Gene Expression in T Lymphocytes and RBL-2H3 Mast Cells Via Thiol Oxidation [PDF]

, 2000
George R. Ehring, Hubert Kerschbaum, Christopher M. Fanger, Claudia Eder, Heiko Rauer, Michael D. Cahalan   +5 more
openalex   +1 more source

YKT6 Promotes Bladder Cancer Progression by Stabilizing β‐catenin Through USP7‐Mediated Deubiquitination

Advanced Science, EarlyView.
The SNARE protein YKT6 is upregulated in bladder cancer (BLCA), correlating with poor prognosis. YKT6 promotes tumor proliferation and metastasis by activating Wnt/β‐catenin signaling. It recruits Ubiquitin‐Specific Peptidase 7 (USP7) to deubiquitinate and stabilize β‐catenin, enhancing its nuclear accumulation and driving oncogenic gene expression ...
Sheng Tu, Wenzhi Du, Yongwen Luo, Jiageng Shi, Tianyun Liu, Meng Ji, Kangping Xiong, Siming Chen, Fenfang Zhou, Mingxing Li, Jingtian Yu, Gang Wang, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Kaiyu Qian   +16 more
wiley   +1 more source

Akkermansia muciniphila- and Pathogenic Bacteria-Derived Endotoxins Differently Regulate Human Dendritic Cell Generation and γδ T Lymphocyte Activation. [PDF]

Biomolecules
Fertitta V, Varano B, Del Cornò M, Fortini P, Aureli A, Conti L.   +5 more
europepmc   +1 more source

Lymphocyte Activation Gene 3 Single-Nucleotide Polymorphisms in Bone Marrow Failure Diseases. [PDF]

Anal Cell Pathol (Amst), 2022
Sun Y, Cao Q, Zhao X, Liu C, Shao Z.
europepmc   +1 more source

lymphocyte-activating factor

Citation: 'lymphocyte-activating factor' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13400 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source