Results 211 to 220 of about 349,873 (260)
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Migration of Activated Lymphocytes
1993When lymphocytes leave the primary lymphoid organs as mature but naive cells, they enter the recirculating pool, moving continuously from the blood into the secondary lymphoid organs, spleen, lymph nodes and Peyer’s patches, from which they return, directly or via efferent lymph, back to the blood (Gowans and Knight 1964).
A, Hamann, S, Rebstock
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The Journal of Immunology, 1973
Abstract Mouse lymphocytes were cultured with phytohemagglutinin or concanavalin A and at various times antiserum to each mitogen was added. Incorporation of thymidine was partially inhibited even when antisera were added after 48 hr. Quantitative analysis of the inhibition produced in normal cultures or cultures containing colchicine ...
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Abstract Mouse lymphocytes were cultured with phytohemagglutinin or concanavalin A and at various times antiserum to each mitogen was added. Incorporation of thymidine was partially inhibited even when antisera were added after 48 hr. Quantitative analysis of the inhibition produced in normal cultures or cultures containing colchicine ...
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Immunology Today, 1981
A review focussing on the lessons learned from polyclonal activation of B cells.
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A review focussing on the lessons learned from polyclonal activation of B cells.
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Lymphocyte Activation in Health and Disease
Critical Reviews in Immunology, 1997Lymphocytes employ a complex assembly of signaling elements that have been organized on a spatiotemporal map to define their role in stimulating both proliferation and apoptosis. The antigen/major histocompatibility complex (MHC) initiates the sequence by organizing the assembly of an active T-cell receptor (TCR) complex responsible for transmitting ...
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T Lymphocyte Activation in Patients with Active Tuberculosis
American Review of Respiratory Disease, 1991Abstract Soluble interleukin-2 receptor (sIL-2R) is a marker of T lymphocyte activation. We measured the amount of serum sIL-2R in 35 patients with active tuberculosis before the initiation of antituberculous treatment. Twenty had pulmonary parenchymal lesion, 8 had tuberculous pleural effusion, and 7 had tuberculous lymphadenitis ...
Leung, JCK, Lai, KN, Lai, CKW, Chan, CHS
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Activation of Human B Lymphocytes
The Journal of Immunology, 1977Abstract The kinetics and mechanisms of suppression of the PWM-induced PFC response of human PB lymphocytes by Con A-activated suppressor cells were investigated. It was necessary that Con A suppressor cells be present early in the preocess of activation of human B cells toward antibody synthesis, but maximal suppression of the PFC ...
Barton F. Haynes, Anthony S. Fauci
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Metabolism of activated T lymphocytes
Current Opinion in Immunology, 2014Activated T cells undergo metabolic reprogramming which promotes glycolytic flux and lactate production as well as elevated production of lipids, proteins, nucleic acids and other carbohydrates (i.e. induction of biomass) even in the presence of oxygen.
Jason A Maciolek +2 more
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Biochemistry of B Lymphocyte Activation
1993The activation of B lymphocytes from resting cells proceeds from the events of early activation to clonal proliferation to final differentiation into either an antibody-secreting plasma cell or a memory B cell. This is a complex activation process marked by several alternative pathways, depending on the nature of the initial antigenic stimulus.
M R, Gold, A L, DeFranco
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Lymphocyte Activation in Angina Pectoris
Clinical Immunology, 1999To determine the role of immune responses in the etiology of coronary angioplasty, the distribution of blood lymphocytes and levels of soluble immune factors in sera of patients with primary unstable angina were determined at pre and post coronary angioplasty.
T A, Smith-Norowitz +6 more
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Off‐Signals in Lymphocyte Activation
Scandinavian Journal of Immunology, 1976High‐dose unresponsiveness to concanavalin A affected T and B lymphocytes equally, although only T cells were activated by Con A. Thus, activation and inactivation signals art totally unrelated, the latter also lacking target cell specificity. The off‐signal caused cell death and is probably biologically unimportant.
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