Results 221 to 230 of about 4,241,016 (384)

Nonspecific activation of murine lymphocytes. VI. Mediation of synergistic interaction between T and B lymphocytes by a cell-associated, reciprocally acting lymphocyte proliferation helper. [PDF]

, 1979
M G Goodman, W O Weigle
openalex   +1 more source

Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision

Advanced Healthcare Materials, EarlyView.
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja, Lubaba A. Zaman, Chen Zhang, Milankumar Patel, Santhi Gorantla, Prasanta K. Dash, Howard E. Gendelman   +6 more
wiley   +1 more source

Interleukin-18 Binding Protein (IL-18BP) Deficiency Affects Lymphocyte Activation and IL-18 Expression in a Mouse Model of Liver Inflammation. [PDF]

Eur J Immunol
Devisme C, Stosskopf M, Piquet-Pellorce C, Palmer G, Gabay C, Seyec JL, Samson M, Raguenes-Nicol C.   +7 more
europepmc   +1 more source

¹⁸F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models. [PDF]

J Nucl Med, 2023
Le TM, Lee HR, Abt ER, Rashid K, Creech AL, Liang K, Cui J, Cho A, Wei L, Labora A, Chan C, Sanchez E, Kriti K, Karin D, Li L, Wu N, Mona C, Carlucci G, Hugo W, Wu TT, Donahue TR, Czernin J, Radu CG.   +22 more
europepmc   +1 more source

FK 506: Pharmacology and molecular action [PDF]

, 1993
Fung, J, Starzl, TE, Thomson, AW, Woo, J
core  

36 INTERACTION OF LPS AND CONA IN HUMN LYMPHOCYTE ACTIVATION. II: EFFECT ON CELL PROLIFERATION [PDF]

, 1979
Rita Maccario, Luigi Nespoli, V. Monafò, Antonella Vitiello, Antonio Lanzavecchia, Alberto G. Ugazio   +5 more
openalex   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Impact of Multiple Sclerosis Risk Polymorphism rs7665090 on MANBA Activity, Lysosomal Endocytosis, and Lymphocyte Activation. [PDF]

Int J Mol Sci, 2022
González-Jiménez A, López-Cotarelo P, Agudo-Jiménez T, Casanova I, Silanes CL, Martín-Requero Á, Matesanz F, Urcelay E, Espino-Paisán L.   +8 more
europepmc   +1 more source

Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA [PDF]

, 1990
Bach, FH, Duquesnoy, RJ, Eiras, G, Fung, JJ, Starzl, T, Todo, S, Zeevi, A   +6 more
core  

Programmed Aggregation of Lipidated Nitrobenzoselenadiazole as a Photo‐Activatable Pyroptosis Inducer

Advanced Healthcare Materials, EarlyView.
This study presents alkylated nitrobenzoselenadiazole (NBSD) photosensitizers that self‐assemble into programmable aggregates, enabling photo‐triggered pyroptosis and enhanced ROS generation. The lead compound, NBSD‐NOc, exhibits superior photodynamic activity, high cellular uptake, and implantable gel compatibility with pH‐responsive release.
Jong Min An, Hyunyoung Choi, Hyo In Kim, Do‐Yeon Kim, Jahyun Kim, Jinbong Park, Junyang Jung, Na Young Jeong, Dokyoung Kim   +8 more
wiley   +1 more source