Results 201 to 210 of about 115,529 (261)

High SOX17 expression is correlated with favorable prognosis and CD8(+) TILs expression in patients with pancreatic cancer after curative resection. [PDF]

Transl Oncol
Yu J, Pan Y, Chen Y, Shu Z, Ma L, Wu B, Li J, Li J, Lan C.   +8 more
europepmc   +1 more source

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Severe Cryptosporidiosis Following Tumor-Infiltrating Lymphocyte Therapy in a Patient With Metastatic Mucosal Melanoma. [PDF]

ACG Case Rep J
Gill G, Saab O, Patel K, Bhattacharyya AK, Roden D, Aggarwal A.   +5 more
europepmc   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

A computer vision method to evaluate tumor-infiltrating lymphocytes and multiparametric modeling of neoadjuvant systemic therapy response in breast cancer. [PDF]

Ther Adv Med Oncol
Bielecki M, Lu FI, Vo A, Rakovitch E, Jerzak KJ, Salgado R, Karshafian R, Tran WT.   +7 more
europepmc   +1 more source

A novel mouse model of chronic Pseudomonas aeruginosa infection inducing bronchiectasis‐like phenotype

Animal Models and Experimental Medicine, EarlyView.
This graphical abstract highlights a bronchiectasis mouse model driven by chronic Pseudomonas aeruginosa (CPA)‐loaded agar beads plus papain, which reproduces significant airway structural damage, inflammation, mucous overproduction, and functional impairment, providing a clinically relevant platform for studying disease mechanisms and evaluating ...
Heng Yang, Yang Liu, Yuqing Wang, Yuhua Wen, Yan Chen, Rui Fan, Jiayan Xu, Shunlian Hu, Hao Qian, Rui Jiang, Weijun Cao, Jinfu Xu   +11 more
wiley   +1 more source

Error in Tables 2 and 3.

JAMA Oncol
europepmc   +1 more source

Characterisation of tumor-infiltrating gamma-delta T cells in human colorectal cancer with MHC-I loss. [PDF]

Clin Transl Immunology
Li TA, Quigley LT, Chan KF, Williams DS, Mielke LA, Behren A, Da Gama Duarte J.   +6 more
europepmc   +1 more source