2-Deoxy-D-glucose inhibits lymphocytic choriomeningitis virus propagation by targeting glycoprotein N-glycosylation [PDF]
Virology Journal, 2023 Background Increased glucose uptake and utilization via aerobic glycolysis are among the most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that similar metabolic changes are also triggered in many virus-infected cells ...
Lucia Baďurová +5 more
doaj +2 more sources
Lymphocytic choriomeningitis arenavirus utilises intercellular connections for cell to cell spread [PDF]
Scientific ReportsThe Arenaviridae family of segmented RNA viruses contains nearly 70 species with several associated with fatal haemorrhagic fevers, including Lassa, Lujo and Junin viruses.
Owen Byford +9 more
doaj +2 more sources
Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone [PDF]
, 2014 Lymphocytic choriomeningitis virus (LCMV) can be transmitted through congenital infection, leading to persistent infection of numerous organ systems including the central nervous system (CNS).
Klein, Robyn S +2 more
core +10 more sources
Risk of infections transmitted by arthropods and rodents in forestry workers. [PDF]
, 1994 One hundred and fifty-one forestry workers and 151 matched office clerks were compared as to the presence of antibodies against Borelia burgdorferi, tick-borne encephalitis virus, Puumalavirus and lymphocytic choriomeningitis virus.
A. D. M. E. Osterhaus +16 more
core +5 more sources
Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET
Nature Communications, 2022 The innate antiviral immune response is an important defense against infection. Here, the authors show that leukocyte cell-derived chemotaxin 2 (LECT2) promotes RIG-I-mediated innate immune responses by preventing its degradation, and inhibits ...
Takayoshi Shirasaki +29 more
doaj +1 more source
Slow viral propagation during initial phase of infection leads to viral persistence in mice
Communications Biology, 2021 Using different strains of the lymphocytic choriomeningitis virus (LCMV), Xu, Wang et al. show that a slow viral propagation limits type I interferon (IFN-I) production and viral persistence in mice.
Haifeng C. Xu +14 more
doaj +1 more source
A new arenavirus in a cluster of fatal transplant-associated diseases [PDF]
, 2008 Three patients who received visceral-organ transplants from a single donor on the same day died of a febrile illness 4 to 6 weeks after transplantation.
Birch, Chris +17 more
core +4 more sources
Novel Arenavirus Infection in Humans, United States
Emerging Infectious Diseases, 2011 Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses.
Mary Louise Milazzo +2 more
doaj +1 more source
Nature Communications, 2021 Lymphocytic choriomeningitis virus (LCMV)-based viral vectors have been shown to induce potent antitumor immune responses. Here the authors show that a LCMV-based vaccine vector remodels the tumor-associated fibroblastic stroma, sustaining CD8+ T cell ...
Sandra S. Ring +19 more
doaj +1 more source