Results 41 to 50 of about 25,376 (203)

LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION

Problems of Infectious and Parasitic Diseases
Background: Lymphocytic choriomeningitis virus (LHMV) infection is a neglected rodent-borne zoonotic infection but it is found all over the world because of the cosmopolitan distribution of its reservoirs.
Teodora Gladnishka, Iva Trifonova, Vladislava Ivanova, Iva Christova   +3 more
doaj   +1 more source

Lymphocytic Choriomeningitis Virus–associated Meningitis, Southern Spain

Emerging Infectious Diseases, 2012
Lymphocytic choriomeningitis virus (LCMV) was detected in 2 patients with acute meningitis in southern Spain within a 3-year period. Although the prevalence of LCMV infection was low (2 [1.3%] of 159 meningitis patients), it represents 2.9% of all ...
Mercedes Pérez-Ruiz, José-María Navarro-Marí, María-Paz Sánchez-Seco, María-Isabel Gegúndez, Gustavo Palacios, Nazir Savji, W. Ian Lipkin, Giovanni Fedele, Fernando de Ory-Manchón   +8 more
doaj   +1 more source

Gene therapy of malignant glioma with retroviral vectors and tumor-infiltrating progenitor cells [PDF]

, 2008
Gene therapy as a therapeutic strategy in the treatment of human gliomas is limited by the efficacy of gene transfer and intratumoral distribution of viral vectors.
Miletic, Hrvoje
core  

Screening donors for xenotransplantation: The potential for xenozoonoses [PDF]

, 1994
Xenotransplantation is a potential solution to the current donor shortage for solid organ transplantation. The transmission of infectious agents from donor organs or bone marrow to the recipient is a well-recognized phenomenon following ...
Kahleen, B, Kalter, S, McMichael, JP, Michaels, MG, Peters, RL, Simmons, RL, Starzl, TE   +6 more
core   +1 more source

Tradeoffs between brain and digestive tissues across elevations in Typhlomys daloushanensis: evidence for sexual dimorphism

Wildlife Biology, EarlyView.
To cope with highly stochastic and/or heterogeneous environmental conditions, animals must balance energy resource allocation across physiological processes. The digestive tract and brain exhibit structural variations under strong developmental and selective pressures that vary across environmental gradients both between and within species.
Yimei Yan, Bangqing Chen, Jifa Cui, Chris Newman, Boyu Lei, Nan Wu, Jinwei Wu, Jin Zhao, Christina D. Buesching, Youbing Zhou   +9 more
wiley   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

Nature Communications, 2018
Chronic viral infections are frequently associated with the dysfunction of CD8+ T cells which includes loss of function and results in CD8+ T cell exhaustion.
Vishal Khairnar, Vikas Duhan, Ashwini M. Patil, Fan Zhou, Hilal Bhat, Christine Thoens, Piyush Sharma, Tom Adomati, Sarah-Kim Friendrich, Judith Bezgovsek, Janine D. Dreesen, Gunther Wennemuth, Astrid M. Westendorf, Gennadiy Zelinskyy, Ulf Dittmer, Cornelia Hardt, Jörg Timm, Joachim R. Göthert, Philipp A. Lang, Bernhard B. Singer, Karl S. Lang   +20 more
doaj   +1 more source

Independent Lineage of Lymphocytic Choriomeningitis Virus in Wood Mice (Apodemus sylvaticus), Spain

Emerging Infectious Diseases, 2009
To clarify the presence of lymphocytic choriomeningitis virus (LCMV) in Spain, we examined blood and tissue specimens from 866 small mammals. LCMV RNA was detected in 3 of 694 wood mice (Apodemus sylvaticus).
Juan Ledesma, Cesare Giovanni Fedele, Francisco Carro, Lourdes Lledó, María Paz Sánchez-Seco, Antonio Tenorio, Ramón Casimiro Soriguer, José Vicente Saz, Gerardo Domínguez, María Flora Rosas, Jesús Félix Barandika, María Isabel Gegúndez   +11 more
doaj   +1 more source

Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses

Cell Reports, 2020
Summary: Persistent viral infections subvert key elements of adaptive immunity. To compare germinal center (GC) B cell responses in chronic and acute lymphocytic choriomeningitis virus infection, we exploit activation-induced deaminase (AID) fate ...
Bénédict Fallet, Yi Hao, Marianna Florova, Karen Cornille, Alba Verge de los Aires, Giulia Girelli Zubani, Yusuf I. Ertuna, Victor Greiff, Ulrike Menzel, Karim Hammad, Doron Merkler, Sai T. Reddy, Jean-Claude Weill, Claude-Agnès Reynaud, Daniel D. Pinschewer   +14 more
doaj   +1 more source

T cells can mediate viral clearance from ependyma but not from brain parenchyma in a major histocompatibility class I- and perforin-independent manner [PDF]

, 2017
Viral infection of the central nervous system can lead to disability and death. Yet the majority of viral infections with central nervous system involvement resolve with only mild clinical manifestations, if any. This is generally attributed to efficient
Bergthaler, Andreas, Brück, Wolfgang, Horvath, Edit, Löhning, Max, Merkler, Doron, Pinschewer, Daniel D., Schedensack, Mariann   +6 more
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