Results 11 to 20 of about 24,842 (206)

2-Deoxy-D-glucose inhibits lymphocytic choriomeningitis virus propagation by targeting glycoprotein N-glycosylation [PDF]

Virology Journal, 2023
Background Increased glucose uptake and utilization via aerobic glycolysis are among the most prominent hallmarks of tumor cell metabolism. Accumulating evidence suggests that similar metabolic changes are also triggered in many virus-infected cells ...
Lucia Baďurová, Katarína Polčicová, Božena Omasta, Ingrid Ovečková, Eva Kocianová, Jana Tomášková   +5 more
doaj   +2 more sources

LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION

Problems of Infectious and Parasitic Diseases
Background: Lymphocytic choriomeningitis virus (LHMV) infection is a neglected rodent-borne zoonotic infection but it is found all over the world because of the cosmopolitan distribution of its reservoirs.
Teodora Gladnishka, Iva Trifonova, Vladislava Ivanova, Iva Christova   +3 more
doaj   +3 more sources

Lymphocytic Choriomeningitis Virus Infections in Hungary between 2017–2023—Investigation of the First Congenital Infections [PDF]

Diagnostics
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne arenavirus, primarily spread by common house mouse species. Acquired human infections range from asymptomatic to mild flu-like symptoms and self-resolving neurological diseases.
Anita Koroknai, Anna Nagy, Orsolya Nagy, Nikolett Csonka, Eszter Mezei, Katalin Szomor, Mária Takács   +6 more
doaj   +2 more sources

Retrospective Screening for Zoonotic Viruses in Encephalitis Cases in Austria, 2019–2023, Reveals Infection with Lymphocytic Choriomeningitis Virus but Not with Rustrela Virus or Tahyna Virus [PDF]

Viruses
Zoonotic viruses may be neglected as etiologies of meningoencephalitis in humans. We performed retrospective testing of cerebrospinal fluid from encephalitis cases in biobank material for three zoonotic or potentially zoonotic viruses: rustrela virus ...
Jeremy V. Camp, Norbert Nowotny, Stephan W. Aberle, Monika Redlberger-Fritz   +3 more
doaj   +2 more sources

Lymphocytic Choriomeningitis Virus Alters the Expression of Male Mouse Scent Proteins [PDF]

Viruses, 2021
Mature male mice produce a particularly high concentration of major urinary proteins (MUPs) in their scent marks that provide identity and status information to conspecifics.
Michael B. A. Oldstone, Brian C. Ware, Amanda Davidson, Mark C. Prescott, Robert J. Beynon, Jane L. Hurst   +5 more
doaj   +2 more sources

Local Maintenance and Genomic Diversity of Lymphocytic Choriomeningitis Virus in Natural Populations of House Mice in the Czech Republic Over a 24-Year Period. [PDF]

Zoonoses Public Health
ABSTRACT Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent‐borne zoonotic virus primarily infecting house mice. The virus can be highly pathogenic, particularly in immunocompromised individuals and in congenital infections. LCMV is distributed worldwide but shows local clustering, probably due to the highly structured populations of its ...
Jezkova I, Fornůsková A, Ďureje Ľ, Macholán M, Piálek J, de Bellocq JG.   +5 more
europepmc   +2 more sources

Risk of infections transmitted by arthropods and rodents in forestry workers. [PDF]

, 1994
One hundred and fifty-one forestry workers and 151 matched office clerks were compared as to the presence of antibodies against Borelia burgdorferi, tick-borne encephalitis virus, Puumalavirus and lymphocytic choriomeningitis virus.
A. D. M. E. Osterhaus, A. W. Moll van Charante, AW Moll van Charante, B Ma, B Niklasson, BS Schwartz, CF Stanford, E Schmutzhard, EB Holmgren, J Groen, J. Groen, JE Childs, JMG Jordans, K Hansen, M Nuti, World Health Organisation, WR Rahn   +16 more
core   +5 more sources

Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET

Nature Communications, 2022
The innate antiviral immune response is an important defense against infection. Here, the authors show that leukocyte cell-derived chemotaxin 2 (LECT2) promotes RIG-I-mediated innate immune responses by preventing its degradation, and inhibits ...
Takayoshi Shirasaki, Satoshi Yamagoe, Tetsuro Shimakami, Kazuhisa Murai, Ryu Imamura, Kiyo-Aki Ishii, Hiroaki Takayama, Yukako Matsumoto, Natsumi Tajima-Shirasaki, Naoto Nagata, Ryogo Shimizu, Souma Yamanaka, Atsushi Abe, Hitoshi Omura, Kazunori Kawaguchi, Hikari Okada, Taro Yamashita, Tomoki Yoshikawa, Kazuhiro Takimoto, Motoko Taharaguchi, Shogo Takatsuka, Yoshitsugu Miyazaki, Toshikatsu Tamai, Yamato Tanabe, Makoto Kurachi, Yasuhiko Yamamoto, Shuichi Kaneko, Kunio Matsumoto, Toshinari Takamura, Masao Honda   +29 more
doaj   +1 more source

Slow viral propagation during initial phase of infection leads to viral persistence in mice

Communications Biology, 2021
Using different strains of the lymphocytic choriomeningitis virus (LCMV), Xu, Wang et al. show that a slow viral propagation limits type I interferon (IFN-I) production and viral persistence in mice.
Haifeng C. Xu, Ruifeng Wang, Prashant V. Shinde, Lara Walotka, Anfei Huang, Gereon Poschmann, Jun Huang, Wei Liu, Kai Stühler, Heiner Schaal, Andreas Bergthaler, Aleksandra A. Pandyra, Cornelia Hardt, Karl S. Lang, Philipp A. Lang   +14 more
doaj   +1 more source

Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment

Nature Communications, 2021
Lymphocytic choriomeningitis virus (LCMV)-based viral vectors have been shown to induce potent antitumor immune responses. Here the authors show that a LCMV-based vaccine vector remodels the tumor-associated fibroblastic stroma, sustaining CD8+ T cell ...
Sandra S. Ring, Jovana Cupovic, Lucas Onder, Mechthild Lütge, Christian Perez-Shibayama, Cristina Gil-Cruz, Elke Scandella, Angelina De Martin, Urs Mörbe, Fabienne Hartmann, Robert Wenger, Matthias Spiegl, Andrej Besse, Weldy V. Bonilla, Felix Stemeseder, Sarah Schmidt, Klaus K. Orlinger, Philippe Krebs, Burkhard Ludewig, Lukas Flatz   +19 more
doaj   +1 more source