Results 21 to 30 of about 36,333 (238)

Properties of Defective Lymphocytic Choriomeningitis Virus

Journal of General Virology, 1972
Summary The symptoms and histopathology of many virus diseases depend not so much on damage to the cells by virus but on the immunological reaction to the infection. The earliest (Traub, 1935) and still extensively studied (Oldstone & Dixon, 1970) infection of this type is murine lymphocytic choriomeningitis.
R M, Welsh, C M, O'Connell, C J, Pfau
openaire   +3 more sources

Structural basis for antibody-mediated neutralization of Lymphocytic choriomeningitis virus

bioRxiv, 2022
The mammarenavirus Lymphocytic choriomeningitis virus (LCMV) is a globally distributed zoonotic pathogen that can be lethal in immunocompromised patients and cause severe birth defects if acquired during pregnancy.
Moon-Walker A, Zhang Z, Zyla DS, Buck TK, Li H, Avalos RD, Schendel SL, Hastie KM, Crotty S, Saphire EO.   +9 more
europepmc   +2 more sources

Congenitally acquired persistent lymphocytic choriomeningitis viral infection reduces neuronal progenitor pools in the adult hippocampus and subventricular zone [PDF]

, 2014
Lymphocytic choriomeningitis virus (LCMV) can be transmitted through congenital infection, leading to persistent infection of numerous organ systems including the central nervous system (CNS).
Klein, Robyn S, Sun, Tony, Vasek, Michael J   +2 more
core   +10 more sources

Risk of infections transmitted by arthropods and rodents in forestry workers. [PDF]

, 1994
One hundred and fifty-one forestry workers and 151 matched office clerks were compared as to the presence of antibodies against Borelia burgdorferi, tick-borne encephalitis virus, Puumalavirus and lymphocytic choriomeningitis virus.
A. D. M. E. Osterhaus, A. W. Moll van Charante, AW Moll van Charante, B Ma, B Niklasson, BS Schwartz, CF Stanford, E Schmutzhard, EB Holmgren, J Groen, J. Groen, JE Childs, JMG Jordans, K Hansen, M Nuti, World Health Organisation, WR Rahn   +16 more
core   +5 more sources

Transmission of lymphocytic choriomeningitis virus by organ transplantation.

New England Journal of Medicine, 2006
S. Fischer, M. Graham, M. Kuehnert, C. Kotton, A. Srinivasan, F. Marty, J. A. Comer, J. Guarner, C. Paddock, D. Demeo, W. Shieh, B. Erickson, U. Bandy, A. DeMaria, J. P. Davis, F. Delmonico, B. Pavlin, A. Likos, Martin J. Vincent, Tara K. Sealy, C. Goldsmith, D. Jernigan, P. Rollin, Michelle M. Packard, Mitesh M. Patel, C. Rowland, R. Helfand, S. Nichol, J. Fishman, T. Ksiazek, S. Zaki   +30 more
semanticscholar   +3 more sources

Leukocyte cell-derived chemotaxin 2 is an antiviral regulator acting through the proto-oncogene MET

Nature Communications, 2022
The innate antiviral immune response is an important defense against infection. Here, the authors show that leukocyte cell-derived chemotaxin 2 (LECT2) promotes RIG-I-mediated innate immune responses by preventing its degradation, and inhibits ...
Takayoshi Shirasaki, Satoshi Yamagoe, Tetsuro Shimakami, Kazuhisa Murai, Ryu Imamura, Kiyo-Aki Ishii, Hiroaki Takayama, Yukako Matsumoto, Natsumi Tajima-Shirasaki, Naoto Nagata, Ryogo Shimizu, Souma Yamanaka, Atsushi Abe, Hitoshi Omura, Kazunori Kawaguchi, Hikari Okada, Taro Yamashita, Tomoki Yoshikawa, Kazuhiro Takimoto, Motoko Taharaguchi, Shogo Takatsuka, Yoshitsugu Miyazaki, Toshikatsu Tamai, Yamato Tanabe, Makoto Kurachi, Yasuhiko Yamamoto, Shuichi Kaneko, Kunio Matsumoto, Toshinari Takamura, Masao Honda   +29 more
doaj   +1 more source

Slow viral propagation during initial phase of infection leads to viral persistence in mice

Communications Biology, 2021
Using different strains of the lymphocytic choriomeningitis virus (LCMV), Xu, Wang et al. show that a slow viral propagation limits type I interferon (IFN-I) production and viral persistence in mice.
Haifeng C. Xu, Ruifeng Wang, Prashant V. Shinde, Lara Walotka, Anfei Huang, Gereon Poschmann, Jun Huang, Wei Liu, Kai Stühler, Heiner Schaal, Andreas Bergthaler, Aleksandra A. Pandyra, Cornelia Hardt, Karl S. Lang, Philipp A. Lang   +14 more
doaj   +1 more source

A new arenavirus in a cluster of fatal transplant-associated diseases [PDF]

, 2008
Three patients who received visceral-organ transplants from a single donor on the same day died of a febrile illness 4 to 6 weeks after transplantation.
Birch, Chris, Briese, Thomas, Catton, Mike, Conlan, Sean, Druce, Julian, Du, Lei, Egholm, Michael, Goldsmith, Cynthia S., Hui, Jeffrey, Lipkin, W. Ian, Marshall, John, Paddock, Christopher D., Palacios, Gustavo F., Quan, Phuong-Lan, Shieh, Wun-Ju, Simons, Jan Fredrik, Tran, Thomas, Zaki, Sherif R.   +17 more
core   +4 more sources

Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment

Nature Communications, 2021
Lymphocytic choriomeningitis virus (LCMV)-based viral vectors have been shown to induce potent antitumor immune responses. Here the authors show that a LCMV-based vaccine vector remodels the tumor-associated fibroblastic stroma, sustaining CD8+ T cell ...
Sandra S. Ring, Jovana Cupovic, Lucas Onder, Mechthild Lütge, Christian Perez-Shibayama, Cristina Gil-Cruz, Elke Scandella, Angelina De Martin, Urs Mörbe, Fabienne Hartmann, Robert Wenger, Matthias Spiegl, Andrej Besse, Weldy V. Bonilla, Felix Stemeseder, Sarah Schmidt, Klaus K. Orlinger, Philippe Krebs, Burkhard Ludewig, Lukas Flatz   +19 more
doaj   +1 more source

Novel Arenavirus Infection in Humans, United States

Emerging Infectious Diseases, 2011
Immunoglobulin G against Whitewater Arroyo virus or lymphocytic choriomeningitis virus was found in 41 (3.5%) of 1,185 persons in the United States who had acute central nervous system disease or undifferentiated febrile illnesses.
Mary Louise Milazzo, Grant L. Campbell, Charles F. Fulhorst   +2 more
doaj   +1 more source