Results 11 to 20 of about 36,333 (238)

CD164 is a host factor for lymphocytic choriomeningitis virus entry. [PDF]

Proc Natl Acad Sci U S A, 2022
Significance Lymphocytic choriomeningitis virus (LCMV) is the prototypic arenavirus and has been utilized for decades as a model to understand the host immune response against viral infection.
Bakkers MJG, Moon-Walker A, Herlo R, Brusic V, Stubbs SH, Hastie KM, Saphire EO, Kirchhausen TL, Whelan SPJ.   +8 more
europepmc   +4 more sources

Lymphocytic Choriomeningitis—Emerging Trends of a Neglected Virus: A Narrative Review

Tropical Medicine and Infectious Disease, 2021
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne zoonotic virus distributed worldwide. Since serologic assays are limited to several laboratories, the disease has been underreported, often making it difficult to determine incidence ...
Tatjana Vilibic-Cavlek, Vladimir Savic, Thomas Ferenc, Anna Mrzljak, Ljubo Barbic, Maja Bogdanic, Vladimir Stevanovic, Irena Tabain, Ivana Ferencak, Snjezana Zidovec-Lepej   +9 more
doaj   +2 more sources

Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence

Journal of Experimental Medicine, 1984
We studied the mechanism of lymphocytic choriomeningitis virus (LCMV) persistence and the suppression of cytotoxic T lymphocyte (CTL) responses in BALB/c WEHI mice infected at birth with LCMV Armstrong strain. Using adoptive transfer experiments we found
Rafi Ahmed, A. Salmi, L. Butler, J. Chiller, M. Oldstone   +4 more
semanticscholar   +3 more sources

Congenital Lymphocytic Choriomeningitis Virus [PDF]

Journal of Child Neurology, 2013
Lymphocytic choriomeningitis virus is a rodent-borne arenavirus that can cause congenital infection affecting the developing central nervous system. When the infection occurs during pregnancy, the virus targets the fetal brain and retina, potentially causing ventriculomegaly, hydrocephalus, chorioretinitis, and neurodevelopmental abnormalities. It has
Jacqueline L, Anderson, Philip Thaler, Levy, Kathryn B, Leonard, Christopher D, Smyser, Lawrence, Tychsen, F Sessions, Cole   +5 more
openaire   +3 more sources

H-2 compatability requirement for T-cell-mediated lysis of target cells infected with lymphocytic choriomeningitis virus. Different cytotoxic T- cell specificities are associated with structures coded for in H-2K or H-2D;

Journal of Experimental Medicine, 1975
Use of syngeneic, allogeneic, F1, AND H-2 recombinatn mice has shown that animals injected with lymphocytic choriomeningitis (LCM) virus generate T cells which are cytotoxic for H-2K or H-2D compatible, but not H-2 different, virus-infected target cells.
R. Zinkernagel, P. Doherty
semanticscholar   +3 more sources

LYMPHOCYTIC CHORIOMENINGITIS VIRUS INFECTION

Problems of Infectious and Parasitic Diseases
Background: Lymphocytic choriomeningitis virus (LHMV) infection is a neglected rodent-borne zoonotic infection but it is found all over the world because of the cosmopolitan distribution of its reservoirs.
Teodora Gladnishka, Iva Trifonova, Vladislava Ivanova, Iva Christova   +3 more
doaj   +3 more sources

Immune Exhaustion: Past Lessons and New Insights from Lymphocytic Choriomeningitis Virus

Viruses, 2019
Lymphocytic choriomeningitis virus (LCMV) is a paradigm-forming experimental system with a remarkable track record of contributing to the discovery of many of the fundamental concepts of modern immunology.
Shannon M. Kahan, Allan J. Zajac
doaj   +2 more sources

IMMUNOPATHOGENESIS OF ACUTE CENTRAL NERVOUS SYSTEM DISEASE PRODUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS

Journal of Experimental Medicine, 1972
Lymphocytic choriomeningitis (LCM) virus carriers were established by intracerebral inoculation of adult BALB/c mice followed by a single dose of cyclophosphamide (CY) (150 mg/kg) 3 days after infection, and by intracerebral injection within 24 hr of ...
D. Gilden, G. A. Cole, N. Nathanson
semanticscholar   +4 more sources

Lymphocytic Choriomeningitis Virus Infections in Hungary between 2017–2023—Investigation of the First Congenital Infections [PDF]

Diagnostics
Lymphocytic choriomeningitis virus (LCMV) is a neglected rodent-borne arenavirus, primarily spread by common house mouse species. Acquired human infections range from asymptomatic to mild flu-like symptoms and self-resolving neurological diseases.
Anita Koroknai, Anna Nagy, Orsolya Nagy, Nikolett Csonka, Eszter Mezei, Katalin Szomor, Mária Takács   +6 more
doaj   +2 more sources

Retrospective Screening for Zoonotic Viruses in Encephalitis Cases in Austria, 2019–2023, Reveals Infection with Lymphocytic Choriomeningitis Virus but Not with Rustrela Virus or Tahyna Virus [PDF]

Viruses
Zoonotic viruses may be neglected as etiologies of meningoencephalitis in humans. We performed retrospective testing of cerebrospinal fluid from encephalitis cases in biobank material for three zoonotic or potentially zoonotic viruses: rustrela virus ...
Jeremy V. Camp, Norbert Nowotny, Stephan W. Aberle, Monika Redlberger-Fritz   +3 more
doaj   +2 more sources