Results 31 to 40 of about 36,333 (238)

Severe congenital chorioretinitis caused by congenital lymphocytic choriomeningitis virus infection

open access: yesAmerican Journal of Ophthalmology Case Reports, 2021
Purpose: To describe a case of congenital lymphocytic choriomeningitis virus (LCMV), a potentially severe and under-diagnosed etiology of congenital chorioretinitis. Observations: A 5-month old boy presented with esotropia.
Nadia Ansari   +3 more
doaj   +1 more source

Lymphocytic choriomeningitis virus [PDF]

open access: yesCanadian Medical Association Journal, 2005
Background and epidemiology: In May 2005, the US Centers for Disease Control and Prevention (CDC) reported cases of lymphocytic choriomeningitis virus (LCMV) infection in 4 people who had received transplants of the liver, lungs or a kidney from a single common donor.
openaire   +2 more sources

Widespread recombination, reassortment, and transmission of unbalanced compound viral genotypes in natural arenavirus infections. [PDF]

open access: yes, 2015
Arenaviruses are one of the largest families of human hemorrhagic fever viruses and are known to infect both mammals and snakes. Arenaviruses package a large (L) and small (S) genome segment in their virions.
Chang, Li-Wen   +13 more
core   +7 more sources

Envelope Exchange for the Generation of Live-Attenuated Arenavirus Vaccines. [PDF]

open access: yesPLoS Pathogens, 2006
Arenaviruses such as Lassa fever virus cause significant mortality in endemic areas and represent potential bioterrorist weapons. The occurrence of arenaviral hemorrhagic fevers is largely confined to Third World countries with a limited medical ...
Andreas Bergthaler   +5 more
doaj   +2 more sources

Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies

open access: yesMolecular Therapy: Oncolytics, 2016
The systemic delivery of therapeutic viruses, such as oncolytic viruses or vaccines, is limited by the generation of neutralizing antibodies. While pseudotyping of rhabdoviruses with the lymphocytic choriomeningitis virus glycoprotein has previously ...
Laura Evgin   +17 more
doaj   +1 more source

Lymphocytic choriomeningitis virus Clone 13 infection causes either persistence or acute death dependent on IFN-1, cytotoxic T lymphocytes (CTLs), and host genetics

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance T cell exhaustion and successful therapy to restore T cell function initially uncovered with lymphocytic choriomeningitis virus (LCMV) Clone (Cl) 13 infection is important for understanding and treating persistent viral infections and ...
M. Oldstone   +7 more
semanticscholar   +1 more source

Hantavirus and Arenavirus Antibodies in Persons with Occupational Rodent Exposure, North America

open access: yesEmerging Infectious Diseases, 2007
Rodents are the principal hosts of Sin Nombre virus, 4 other hantaviruses known to cause hantavirus pulmonary syndrome in North America, and the 3 North American arenaviruses.
Charles F. Fulhorst   +7 more
doaj   +1 more source

Isolation and genomic characterization of lymphocytic choriomeningitis virus in ticks from northeastern China

open access: yesTransboundary and Emerging Diseases, 2018
Lymphocytic choriomeningitis virus (LCMV) is a rodent-borne arenavirus that is considered a neglected cause of neurologic diseases in humans. In this study, we described genomic characterization of newly isolated LCMVs in Haemaphysalis longicornis ...
Li Zhang   +7 more
semanticscholar   +1 more source

Polyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverage [PDF]

open access: yes, 2010
Background Several arenaviruses cause severe hemorrhagic fever and aseptic meningitis in humans for which no licensed vaccines are available. A major obstacle for vaccine development is pathogen heterogeneity within the Arenaviridae family.
Maya F Kotturi   +12 more
core   +2 more sources

Adoptive B cell therapy for chronic viral infection

open access: yesFrontiers in Immunology, 2022
T cell-based therapies have been widely explored for the treatment of cancer and chronic infection, but B cell-based therapies have remained largely unexplored.
Young Rock Chung   +4 more
doaj   +1 more source

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