Results 161 to 170 of about 37,501 (261)

Assessing Risk Thresholds in Controlled Human Infection Models (CHIM)

Bioethics, Volume 40, Issue 5, Page 519-529, June 2026.
ABSTRACT Controlled Human Infection Models (CHIMs) are a type of clinical trial involving deliberately exposing human volunteers to an infectious agent. Compared to studies of natural infection, CHIMs offers distinctive benefits, from the ability to study presymptomatic infection to a direct assessment of the efficacy of vaccines and therapeutics in a ...
Alexa Nord‐Bronzyk, Barnaby Young, Jerry Menikoff, Julian Savulescu, G. Owen Schaefer   +4 more
wiley   +1 more source

Early detection of urological malignancies in Lynch syndrome: a systematic review. [PDF]

Fam Cancer
Doornweerd BHJ, Rasmussen MW.
europepmc   +1 more source

Pre‐service teachers' explicit and implicit stereotypes towards pupils with different special educational needs

British Journal of Educational Psychology, Volume 96, Issue 2, Page 612-630, June 2026.
Abstract Background Successful inclusion in education depends heavily on the attitudes of teachers, and stereotypes play a significant role in shaping these attitudes. However, social desirability bias may limit direct measures of stereotypes. Combining direct and indirect measures offers better insights.
Charlotte S. Schell, Hannah Kleen, Charlotte Dignath, Nathalie John, Mareike Kunter   +4 more
wiley   +1 more source

Pancreatic Neuroendocrine Tumor in Lynch Syndrome: Expanding the Tumor Spectrum of Mismatch Repair Deficiency. [PDF]

Cureus
Mudupula Vemula SS, Sanka S, Natarajan V, Varghese MT, Isaac D.   +4 more
europepmc   +1 more source

Evolutionary Footprint: A Systemic Indicator in Evolution, Ecology and Conservation

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT The growing awareness of evolutionary responses to human‐induced environmental changes highlights the need to better understand and integrate evolutionary perspectives into life sciences and, more broadly, into biodiversity conservation. Evolutionary changes are complex and multi‐causal, operating across numerous timescales.
Thibault Genissel, Alexandre Robert, Jane Lecomte, François Sarrazin   +3 more
wiley   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, Volume 178, Issue 2, Page 261-268, June 2026.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

Risk-reducing gynecologic surgery decisions in Lynch syndrome at a safety-net hospital and university medical center. [PDF]

Gynecol Oncol
Waggoner RM, Ricker CN, Nie Q, Guo XM, Comeaux JG, Chang EY, Gutierrez N, Hernandez D, Nguyen A, Garcia I, Ito F, Brunette LL, Roman LD, Spicer D, Culver JO.   +14 more
europepmc   +1 more source

Intrahepatic Cholangiocarcinoma: Epidemiological Trends, Risk Factors, Diagnostic Challenges, and Advances in Personalized Therapy—A Comprehensive Review

Journal of Gastroenterology and Hepatology, Volume 41, Issue 6, Page 1701-1721, June 2026.
ABSTRACT Intrahepatic cholangiocarcinoma (iCCA) ranks as the second most common primary liver cancer, compared to about 20% of cases. Its global incidence has climbed over the past four decades, yet early detection remains indefinable due to its asymptomatic nature. Five‐year survival rate of approximately is under 10%.
Yaqoob Muhammad, YuZhu Jin, Kai Luo, He Bai, Xudong Zhang, Xu Sun, Zahoor Maheen, Ali Tanveer, Saeed Muddasar Muhammad, Jialin Qu, Guixin Zhang   +10 more
wiley   +1 more source

MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk. [PDF]

Gut
Yang H, Dungan M, Madhu B, Beyries K, Wang X, Kilpatrick R, Chen B, Oh S, Berkowitz M, Smith D, Zhou C, Koralov SB, Axelrad J, Lengner CJ, Belle N, Bewtra M, Katona BW, Cadwell K.   +17 more
europepmc   +1 more source

Pathogenic Variants in the PRKRA Gene Can Result in a Rapid‐Onset Dystonia‐Parkinsonism‐like Phenotype

Movement Disorders, Volume 41, Issue 6, Page 1602-1604, June 2026.
Maeve Bradley, Senan Maher, Christian Espinoza‐Vinces, Kathleen Gorman, Tim Lynch, Richard A. Walsh, Alberto J. Espay, Conor Fearon   +7 more
wiley   +1 more source