Results 151 to 160 of about 37,501 (261)
Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes +6 more
wiley +1 more source
Lynch syndrome and urologic malignancies: a contemporary review
PURPOSE OF REVIEW: An overview of urologic malignancies in Lynch syndrome and the current state of research. RECENT FINDINGS: Upper tract urothelial carcinoma (UTUC) is the third most common malignancy in Lynch syndrome.
Lim A., Matin S.F., Rao P.
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This article systematically elucidates the molecular mechanisms of colorectal precancerous lesions, introduces cutting‐edge research tools like multi‐omics and organoids, and highlights the potential and prospects of natural products such as berberine, resveratrol, and curcumin in preventing and intervening in colorectal carcinogenesis by modulating ...
Shunji Liu +6 more
wiley +1 more source
Lynch Syndrome in the Asian American Population: A Review of the Literature. [PDF]
Park W, Mochizuki A, Gima L, Jeter JM.
europepmc +1 more source
Three molecular pathways model colorectal carcinogenesis in Lynch syndrome
Lynch syndrome is caused by germline mutations of DNA mismatch repair (MMR) genes. MMR deficiency has long been regarded as a secondary event in the pathogenesis of Lynch syndrome colorectal cancers.
Ballhausen A +10 more
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Diagnosis of Lynch syndrome based on pathologic examination
Lynch syndrome is an autosomal dominant disease predisposing to cancer development. Up to 5 % of colorectal cancers may be associated with Lynch syndrome. Due to its familial occurrence the diagnosis is important for family screening.
KRAUSOVÁ, Lenka
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Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu +3 more
wiley +1 more source
Why patient organizations are important to improve care for people with Lynch syndrome. [PDF]
Seppen J.
europepmc +1 more source
Abstract Parents of children with special needs in Nigeria are faced with several challenges. In most cases, decisions are taken without their active involvement, despite them being the primary carers for their children with special needs. This research utilised a qualitative research design with fifteen participants to understand parents' perspectives
Noah Agbo, Sylvia Yeboah Boamah
wiley +1 more source
Prevention strategies for hereditary gynaecological cancer in Lynch syndrome. [PDF]
Kwinten KJJ +5 more
europepmc +1 more source

