Results 141 to 150 of about 1,289,326 (214)

Integrative Multi‐Omics Profiling Reveals Age‐Associated Genomic and Tumor Microenvironmental Heterogeneity in Colorectal Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Integrated multi‐omics analysis defines an age‐resolved molecular–immune framework in colorectal cancer. Early‐onset tumors show reduced APC/KRAS alterations, frequent SMAD4 disruption, enriched PTPRK–RSPO3 fusions, and increased CD4+ memory T cells and mast cells with greater checkpoint responsiveness.
Yang Guo, Yajiao He, Tao Zhou, Haidong Zhang, Fei Liao, Yuelan Wang, Hai‐Ning Chen, Li‐Bin Huang, Xuyang Xia, Yiqi Deng, Jing Wu, Siyu Yang, Heng Xu, Zong‐Guang Zhou, Yang Shu, Lie Yang   +15 more
wiley   +1 more source

Routes to colorectal cancer in Lynch syndrome: a decade of molecular and clinical insights converging on Schrödinger's cat. [PDF]

Fam Cancer
Ahadova A, Fayyaz F, Marin Grez L, Bläker H, Kloor M.   +4 more
europepmc   +1 more source

Knowledge gaps in tubular gut tumours: a critical appraisal of the 6th edition of the World Health Organization classification of tumours

The Journal of Pathology, Volume 270, Issue 1, Page 4-22, September 2026.
Abstract Gastrointestinal cancer is a global health problem. In the new 6th edition of the World Health Organization Classification of Tumours (WCT) of the Digestive System, updated evidence and guidance is provided for the aetiology, pathogenesis, diagnosis, classification, grading, staging and prognosis of these tumours.
Iris D Nagtegaal, Elizabeth A Montgomery, Alexandros D Polydorides, Anthony J Gill, Motohiro Kojima, Mark J Arends   +5 more
wiley   +1 more source

Adenomas and Beyond: Colonoscopy Surveillance, Racial and Socioeconomic Disparities in Lynch Syndrome. [PDF]

Gastro Hep Adv
Atarere J, Bilalaga MM, Vasireddy R, Mensah B, Gaddipati GN, Singh S, Akhiwu TO, Woo S, Dash C, Kanth P.   +9 more
europepmc   +1 more source

P. Lynch Lee Civil War letter

This collection contains a letter written by P.
Lee, P. Lynch, 1838-1911
core   +1 more source

Exercise-associated epigenetic remodeling and TCR repertoire dynamics in Lynch syndrome carriers. [PDF]

iScience
Wang J, Deng N, Martel-Martel A, Reyes-Uribe L, Thirumurthi S, Duzagac F, Sinha KM, Gilchrist SC, Vilar E.   +8 more
europepmc   +1 more source

Breaking Physiological Barriers in Women's Health: Mucoadhesive and Stimuli‐Responsive Nanomaterials

WIREs Nanomedicine and Nanobiotechnology, Volume 18, Issue 5, September/October 2026.
Drug delivery vehicles generated from biomaterials for women's health. In particular, the breast and the reproductive system, including the ovary, uterus, cervix, vagina, and the surrounding tissues, targeted drug delivery. BioRender. ABSTRACT Biomaterials are natural or synthetic molecules that exhibit biocompatibility, biodegradability, or ...
Maddox Parsons, Alivia R. Parker, Luke Schneider, Trisha Sullivan, Brittany E. Givens   +4 more
wiley   +1 more source

The evolution of hereditary cancer genetic counselling: mainstreaming, service redesign and patient experience in Lynch syndrome. [PDF]

Fam Cancer
Kohut K, Cable S, Ashokan A, Vicari S, Ditchfield H, Young J, Bux B, Lalloo F.   +7 more
europepmc   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, Volume 104, Issue 6, Page 616-637, September 2026.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Fish Consumption and Colorectal Neoplasms among Lynch Syndrome Carriers. [PDF]

J Nutr
Bulbaai MT, Wesselink E, Bisseling TM, Koornstra JJ, van Leerdam ME, Le Marchand L, Newcomb PA, Samadder NJ, Schep-Wijnveen HJ, Kampman E, van Duijnhoven FJ.   +10 more
europepmc   +1 more source