Results 121 to 130 of about 37,501 (261)

For Women, Lynch Syndrome Is About More than Colon Cancer.

, 2019
Click on the Resource Link to access the article (may not be free).Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer, has historically been characterized by a predisposition to colorectal cancer; however, for women with Lynch ...
Parker, Wendy M, Hennig, Kelsey, Burton-Chase, Allison M   +2 more
core   +1 more source

Dysplasia in sessile serrated lesions: frequency, interobserver variability and added value of immunohistochemistry

Histopathology, Volume 89, Issue 1, Page 98-109, July 2026.
Sessile serrated lesions with dysplasia represent a critical step in colorectal carcinogenesis. While routine histologic diagnosis is generally reliable and positive diagnostic trends are observed, subtle dysplastic changes may be overlooked. Targeted use of MLH1 immunohistochemistry provides meaningful diagnostic support in selected sessile serrated ...
Valentina Angerilli, M. Elisa Vink‐Börger, Nanette S. van Roermund, Gesina van Lijnschoten, Chantal C.H.J. Kuijpers, Nicole C.T. van Grieken, Matteo Fassan, Joep E. Ijspeert, Rachel S. van der Post, Iris D. Nagtegaal   +9 more
wiley   +1 more source

Lynch syndrome in the Asian populations

, 2016
© 2016 Dr. Chun How GanLynch syndrome is an autosomal dominant genetic disorder. Mutation carriers are at significant risk of developing colorectal and a variety of extra-colonic cancers, often at a younger age compared to sporadic cancers.
Gan, Chun How
core  

Fas Ligand Expression in Lynch Syndrome-Associated Colorectal Tumours

, 2009
Fas Ligand (FasL) expression by cancer cells may contribute to tumour immune escape via the Fas counterattack against tumour-infiltrating lymphocytes (TILs).
de Vries, Elisabeth G. E.; id_orcid, de Jong, Steven; id_orcid, Hollema, Harry, Koornstra, Jan J., Zwart, Nynke, de Jong, Steven, Boersma-van Eck, Wietske, Kleibeuker, Jan H., de Vries, Elisabeth G. E.   +8 more
core   +1 more source

Understanding of Management Guidelines in Patients with Lynch Syndrome [PDF]

, 2020
Lynch syndrome is an autosomal dominant hereditary cancer syndrome with relatively high prevalence. It is estimated that more than one million Americans have Lynch syndrome, and more than 95% have not been identified.
McDonald, Claire
core  

Feasibility of Physical Fitness Measurements in Older Adults With Intellectual Disabilities Within Two Large Cohort Studies: The HA‐ID and IDS‐TILDA Study

Journal of Intellectual Disability Research, Volume 70, Issue 7, Page 688-699, July 2026.
ABSTRACT Background Research has shown significant underdiagnoses in adults with intellectual disabilities, highlighting the need for objective health measurements to prevent overshadowing. Physical fitness, crucial for health and functioning, is consistently poor in this population, increasing the risk of adverse outcomes.
Alyt Oppewal, Louise Lynch, Eilish Burke
wiley   +1 more source

Mismatch repair genes in Lynch syndrome: a review

São Paulo Medical Journal
Lynch syndrome represents 1-7% of all cases of colorectal cancer and is an autosomal-dominant inherited cancer predisposition syndrome caused by germline mutations in deoxyribonucleic acid (DNA) mismatch repair genes.
Felipe Cavalcanti Carneiro da Silva, Mev Dominguez Valentin, Fábio de Oliveira Ferreira, Dirce Maria Carraro, Benedito Mauro Rossi   +4 more
doaj   +1 more source

Lynch Syndrome Improving Diagnostics and Surveillance [PDF]

, 2018
Lynch syndrome is the most common hereditary predisposition for colorectal cancer and accounts for 2-3% of all colorectal cancer cases. In addition, these patients are also at increased risk of developing extracolonic cancers, especially endometrial ...
Goverde, A. (Anne), Goverde, Anne
core  

Exploring the Integration of Fundamentals of Care Within Strategic Age‐Friendly Hospital Frameworks: A Scoping Review

International Journal of Older People Nursing, Volume 21, Issue 4, July 2026.
ABSTRACT Aim This study examines how the domains of the Fundamentals of Care (FoC) framework are integrated within age‐friendly hospital strategies and to what extent patients and families have been engaged in developing, implementing or evaluating these strategies.
Marianne Saragosa, Rebecca Lemieux, Nathan M. Stall, Jennifer Ridgway   +3 more
wiley   +1 more source

The History of Lynch Syndrome [PDF]

Familial Cancer, 2013
C Richard, Boland, Henry T, Lynch
openaire   +2 more sources