Results 131 to 140 of about 1,289,326 (214)

A POLE P286R‐Mutated Hepatoid Adenocarcinoma of the Lung Showing Substantial Response to Immune Checkpoint Inhibition

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Hepatoid adenocarcinoma of the lung (HAL) is a rare form of lung cancer with histological and morphological properties of hepatocellular carcinoma, characterized by an aggressive course of the disease and unfavorable prognosis. Given the rarity of the pathology and the lack of unambiguous therapeutic protocols, descriptions of ...
Aleksey Chernev   +8 more
wiley   +1 more source

Comprehensive Profiling of ac4C RNA Modification Identifies CERCAM in Cancer‐Associated Fibroblasts as a Key Prognostic and Microenvironmental Regulator in Colorectal Cancer

open access: yesCancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background N4‐acetylcytidine (ac4C) RNA modification has emerged as a critical epigenetic regulator in tumorigenesis and progression. However, the comprehensive landscape of ac4C modification in colorectal cancer (CRC), particularly its orchestration of the tumor microenvironment (TME) and stromal crosstalk, remains largely unexplored.
Yang Xia   +3 more
wiley   +1 more source

What the Dying are Saying to the Living: Mixed Conspecific Alarm Cues Reverse Competitive Hierarchies by Reshaping Genotype‐Specific Life Histories

open access: yesEcology and Evolution, Volume 16, Issue 9, September 2026.
This study demonstrates that the complexity of intraspecific alarm cues—specifically, whether they are from a single genetic source or a mixture—acts as a critical environmental filter. While genotype‐specific cues trigger a canonical adaptive “life‐history switch,” mixed cues induce a state of chronic stress, leading to genotype‐specific reprogramming
Xiaofei Tian   +4 more
wiley   +1 more source

Metastatic Unfunctional Pancreatic Neuroendocrine Tumor in Lynch Syndrome. [PDF]

open access: yesClin Case Rep
Salemi F   +5 more
europepmc   +1 more source

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1151-1171, September 2026.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho   +8 more
wiley   +1 more source

Lynch syndrome-associated urothelial carcinoma: clinical and molecular findings from a single-institution cohort. [PDF]

open access: yesFam Cancer
Rametta A   +19 more
europepmc   +1 more source

A Germline BRCA2 Pathogenic Variant Identified by Multigene Panel Testing in Upper Tract Urothelial Carcinoma

open access: yesIJU Case Reports, Volume 9, Issue 5, September 2026.
ABSTRACT Introduction Upper tract urothelial carcinoma (UTUC) is associated with Lynch syndrome; however, increasing evidence suggests broader genetic heterogeneity. Although multigene panel testing (MGPT) is increasingly adopted internationally, syndrome‐specific genetic testing (SSGT) remains predominant in Japan, potentially limiting detection of ...
Kazuna Matsuo   +6 more
wiley   +1 more source

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