Results 41 to 50 of about 880 (178)
Thiol and disulfide modifications can help alginate carriers adhere to mucus and release drugs in response to reducing environments. This review links modification chemistry to delivery performance and highlights reproducible manufacturing, stability, and safety validation as priorities for clinical translation.
Parteek Prasher +8 more
wiley +1 more source
Poor aqueous solubility limits the anticancer application of tricin (TRI). TRI‐loaded liposomes (TRI@Lips) with favorable physicochemical properties are constructed. The nanoplatform improves cellular uptake, exhibits potent in vitro anti‐gastric‐cancer activity, and accumulates in tumor sites via the EPR effect to achieve dose‐dependent in vivo tumor ...
Baiji Cui +5 more
wiley +1 more source
Background: The present study aims to design formulation of liposomes that are well-preserved during freeze-drying. The combination of Hydroxy Propyl Methyl Cellulose (HPMC) as dispersion matrix and lyoprotectants; maltodextrin or mannitol, was employed ...
Raditya Weka Nugraheni 1, Dwi Setyawan 1, Helmy Yusuf 1 *
doaj +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
Membrane Stability during Biopreservation of Blood Cells [PDF]
Storage methods, which can be taken into consideration for red blood cells and platelets, include liquid storage, cryopreservation and freeze-drying.
Stoll, Christoph +3 more
core +1 more source
This review introduces “Regenerative Microbiology,” a framework that uses bacterial antagonism and phage therapy to address diabetic wound dysbiosis. By activating the p40/EGFR/PI3K axis and providing a vascular‐stratified precision roadmap, this approach shifts the paradigm from antimicrobial suppression to intelligent, microbe‐driven tissue ...
Sabri Saeed Sanabani
wiley +1 more source
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee +8 more
wiley +1 more source
Novel catanionic vesicles from calixarene and single-chain surfactant
The mixed system between p-sulfonatocalix[4]arene and tetradecyltrimethylammonium bromide forms unilamellar vesicles after sonication of the aqueous dispersion.
Jose R. Leis +9 more
core +1 more source
From modular COF design to biomedical translation, this Review maps how linkage chemistry, topology, pore environment, and particle engineering govern bioperformance, therapeutic and diagnostic function, safety, and clinical readiness. Covalent organic frameworks (COFs) are a versatile class of crystalline porous materials with growing potential in ...
Julia Kolodziejczyk +1 more
wiley +1 more source
Impact of Paper Substrates and Storage Conditions on the Stability of Blood Grouping Assays
Four paper‐based blood grouping assays are constructed from cellulose and nitrocellulose, with vertical and lateral flow formats. The optimal storage conditions are determined based on temperature, antibody storage buffer composition, and antibody dilution.
Laura Marcela Rey Gomez +4 more
wiley +1 more source

