Results 81 to 90 of about 880 (178)

Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles

, 2002
The feasibility of producing sterile and freeze-dried polyester nanoparticles was investigated. Various poly(D,L-lactide-co-glycolide) and poly(D,L-lactide) were selected as biodegradable polymers. Using the salting-out procedure, process parameters were
Konan, Yvette N., Gurny, Robert, Allémann, Eric, Konan YN, Gurny R, Allémann E   +5 more
core   +1 more source

Processing and formulation insights for designing quality into lyophilised biopharmaceuticals [PDF]

, 2015
This thesis makes an original contribution to the field of formulation development by providing new experimental data and insights into the effect of processing and formulation conditions on the quality of lyophilised biopharmaceuticals.\ud The quality ...
Beech, Karen E.
core  

Microencapsulation of Lactobacillus bulgaricus and survival assays under simulated gastrointestinal conditions

, 2017
Probiotic Lactobacillus bulgaricus was microencapsulated in whey protein isolate using emulsion technique with transglutaminase-induced gelation and alginate coating.
Liu, Bing-Jie, Li, Xiang-Yi, Meng, Xiang-Hong, Chen, Hai-Yan   +3 more
core   +1 more source

Effect of culture age, protectants, and initial cell concentration on viability of freeze-dried cells ofMetschnikowia pulcherrima

, 2010
The effect of freeze-drying using different lyoprotectants at different concentrations on the viability and biocontrol efficacy of Metschnikowia pulcherrima was evaluated.
Davide Spadaro, Maria Lodovica Gullino, Angelo Garibaldi, Annalisa Alessandra Ciavorella, Jorge Giovanny Lopez-Reyes   +4 more
core   +1 more source

Combination of trehalose and inulin efficacy as lyoprotectant for the preservation of human monocytic cell line

Cryobiology
Traditional cell cryopreservation is expensive and logistically complex, and it necessitates a constant cold chain [44,57]. Lyophilization presents an alluring substitute, so long as the right lyoprotectants are applied to preserve cell integrity [23,40,44,52].
Alina Meiss, Gretel Chometon, Jonas Greinwald, Luis Gautzsch, Kilian Hennes   +4 more
openaire   +2 more sources

Subtilisin-Catalyzed Transesterifications in the Presence of Iron Oxide Nanoparticles in Organic Solvent: Dramatic Catalytic Improvement†

, 2011
Enzymatic transformations in organic media provide a useful methodology for the synthesis of a wide range of enantiomeric compounds.1 In spite of remarkable advances in this field, the enzymes still suffer from a limitation that they display ...
Yunwoong Kim, Sang-Oh Jung, Sang Oh Jung, Mahn-joo Kim, Jong Kyung Bang, Yun-Woong Kim, Jong-Kyung Bang   +6 more
core   +1 more source

Development of PLGA-based itraconazole injectable nanospheres for sustained release

International Journal of Nanomedicine, 2013
Xiaomei Bian,1 Su Liang,1 Jyothy John,1 Cheng-Hui Hsiao,1 Xin Wei,2 Dong Liang,1 Huan Xie1 1Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, 2Department of Chemistry, College of Science and Technology, Texas Southern ...
Bian X, Liang S, John J, Hsiao CH, Wei X, Liang D, Xie H   +6 more
doaj  

Lyophilization and stability of antibody-conjugated mesoporous silica nanoparticle with cationic polymer and PEG for siRNA delivery

International Journal of Nanomedicine, 2018
Worapol Ngamcherdtrakul,1,2,* Thanapon Sangvanich,1,* Moataz Reda,1 Shenda Gu,1 Daniel Bejan,2 Wassana Yantasee1,2 1Department of Biomedical Engineering, Oregon Health and Science University, Portland, OR, USA; 2Nanomedicine Research Unit, PDX ...
Ngamcherdtrakul W, Sangvanich T, Reda M, Gu S, Bejan D, Yantasee W   +5 more
doaj  

Selection of lyoprotectants for the stabilization of the freeze-dried probiotic Limosilactobacillus reuteri CRL 1098 by an accelerated inactivation assay

The high potential of the probiotic L. reuteri CRL 1098, as hypocholesterolemic and vitamin B12 producer strain, would require addressing freeze-drying studies of the microorganism as well as its stability during storage. L.
Font, Graciela Maria, Torino, Maria Ines, Fornaguera, Maria Jose, Taranto, Maria Pia   +3 more
core   +1 more source

Processing and formulation insights for designing quality into lyophilised biopharmaceuticals [PDF]

This thesis makes an original contribution to the field of formulation development by providing new experimental data and insights into the effect of processing and formulation conditions on the quality of lyophilised biopharmaceuticals.
Beech, Karen E.
core