Results 61 to 70 of about 5,663 (168)

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli   +8 more
wiley   +1 more source

Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics

open access: yesDrug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Alexander Boardman   +2 more
wiley   +1 more source

Voltammetric Determination of LSD with a Schiff Base – Chemically Modified Electrode in Aqueous Solution

open access: yesBrazilian Journal of Forensic Sciences, Medical Law and Bioethics, 2020
In recent years, practical, inexpensive, and highly specific electroanalytical methods based on modified electrodes have been increasingly developed for forensic science.
Maria Fernanda M. Ribeiro   +5 more
doaj   +1 more source

The Prevalence of Substance Use Among Students and Associated Factors: A Systematic Review With Narrative Synthesis

open access: yesHealth Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims Substance use is a major public health and social problem that affects individuals of all ages, particularly adolescents and young adults, across every society. School as an educational environment can be suitable for education and orientation towards substances.
Nikta Bazleh
wiley   +1 more source

Metabolomic shifts in beef steers rotationally grazing toxic endophyte-infected tall fescue under fall conditions

open access: yesFrontiers in Veterinary Science
BackgroundFescue toxicosis (FT) results from ingestion of tall fescue infected with the ergot alkaloid (EA)-producing endophyte Epichloë coenophiala. While the vascular system is a major EA target, their biogenic amine-like properties can trigger wider ...
Ignacio M. Llada   +11 more
doaj   +1 more source

Integrating the Mystical Experience Questionnaire Into a Broader Psychometric Framework: English Validation of the Psychedelic Experience Scale and Comparison of Psilocybin and LSD Sessions Across Two Controlled Settings

open access: yesInternational Journal of Methods in Psychiatric Research, Volume 35, Issue 2, June 2026.
ABSTRACT Objectives For English, the validated part of Psychedelic Experience Scale (PES48) is a four‐factor structure called the Mystical Experience Questionnaire (MEQ30). The other validated part of the PES48 consists of four more factors: two more mystical factors (paradoxicality and connectedness, which together with the MEQ30 form the MEQ40), and ...
Kurt Stocker   +8 more
wiley   +1 more source

Analytically Confirmed Opioid Detections From the Emerging Drugs Network of Australia

open access: yesEmergency Medicine Australasia, Volume 38, Issue 3, June 2026.
ABSTRACT Objective We describe analytically confirmed opioid‐related presentations to emergency departments (EDs) in Australia. Methods Presentations with analytically confirmed opioid exposure, between January 2021 and December 2024, were identified from the Emerging Drugs Network of Australia (EDNA) Clinical Registry.
J. Soderstrom   +53 more
wiley   +1 more source

Effects of hallucinogenic drugs on the human heart

open access: yesFrontiers in Pharmacology
Hallucinogenic drugs are used because they have effects on the central nervous system. Their hallucinogenic effects probably occur via stimulation of serotonin receptors, namely, 5-HT2A-serotonin receptors in the brain.
Joachim Neumann   +4 more
doaj   +1 more source

Psychedelics as a potential treatment for tobacco use disorder: a systematic review

open access: yesDiscover Mental Health
Introduction Despite considerable efforts, tobacco use disorder persists as a significant public health issue. The effectiveness of current smoking cessation therapies is limited, leading to a growing interest in alternative treatment approaches such as ...
S. K. Spoelstra   +3 more
doaj   +1 more source

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice

open access: yesFrontiers in Pharmacology, 2018
There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use disorder.
Kenneth Alper   +8 more
doaj   +1 more source

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