Results 61 to 70 of about 2,690,172 (163)

Trends in new psychoactive substance poisonings in the Netherlands: A 14‐year retrospective analysis (2012–2025)

Addiction, Volume 121, Issue 10, Page 2822-2832, October 2026.
Abstract Background and aims Data on the presence of new psychoactive substances (NPS) mainly originate from drug‐checking, law enforcement and wastewater analysis sources, while data on NPS poisonings are scarce. In Europe, the documented incidence rate of NPS poisonings is highest in the Netherlands.
Johanna J. Nugteren‐van Lonkhuyzen, Irma S. van den Hengel‐Koot, Claudine C. Hunault, Dylan W. de Lange, Antoinette J. H. P. van Riel, Laura Hondebrink   +5 more
wiley   +1 more source

Simplified Analogues of Lysergic Acid. II. Derivatives of 3-(o-Tolyl)-n-propylarnine and 1-(o-Tolyl)isopropylamine

, 1959
Several N-alkyl derivatives of 3-(o-tolyl)-n-propylamine and 1-(o-tolyl)isopropyl-amine have been prepared and examined for lysergic acid-like activity.
JC Craig, B Moore, E Ritchie
core   +1 more source

Psychedelics as a Treatment for Alzheimer’s Disease Dementia

Frontiers in Synaptic Neuroscience, 2020
Currently, there are no disease-modifying treatments for Alzheimer’s disease (AD) or any other dementia subtype. The renaissance in psychedelic research in recent years, in particular studies involving psilocybin and lysergic acid diethylamide (LSD ...
Simon Andrew Vann Jones, Allison O’Kelly   +1 more
doaj   +1 more source

MDLSD: study protocol for a randomised, double-masked, placebo-controlled trial of repeated microdoses of LSD in healthy volunteers

Trials, 2021
Background Regular ingestion of sub-hallucinogenic doses of psychedelics, referred to as “microdosing”, has gained increasing popularity and attention in the press and in online forums, with reported benefits across multiple cognitive and emotional ...
Robin J. Murphy, Rachael L. Sumner, William Evans, David Menkes, Ingo Lambrecht, Rhys Ponton, Frederick Sundram, Nicholas Hoeh, Sanya Ram, Lisa Reynolds, Suresh Muthukumaraswamy   +10 more
doaj   +1 more source

Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5‐HT2A receptor

British Journal of Pharmacology, Volume 183, Issue 19, Page 5871-5894, October 2026.
A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga, Robert Kronstrand, Bianca Schranz, Nick van Zijl, Sebastian Karlman, Soma Aref, Tobias Rautio, Svante Vikingsson, Mattias Persson, Henrik Green   +9 more
wiley   +1 more source

Investigating the psychedelic hypothesis of kykeon, the sacred elixir of the Eleusinian Mysteries

Scientific Reports
This study revisits the hypothesis that Claviceps purpurea (Fr.) Tul., a fungus infecting cereals and producing ergot alkaloids (EAs), was the psychedelic agent in kykeon, the sacred elixir of the Eleusinian Mysteries.
Romanos K. Antonopoulos, Evangelos Dadiotis, Kostas Ioannidis, Antigoni Cheilari, Vangelis Mitsis, Ana M. Garcia-Campaña, Laura Gámiz-Gracia, Maykel Hernández-Mesa, Alfonso Narváez, Mark A. Hoffman, Carl A. P. Ruck, Zacharoula Gonou-Zagou, Nektarios Aligiannis, Prokopios Magiatis   +13 more
doaj   +1 more source

Evaluation of 1cp-LSD for Enhancing Welfare in Shelter Dogs: A Randomized Blind Trial with Ethological Intervention

Veterinary Sciences
Shelter environments frequently expose dogs to chronic stress and anxiety, which can compromise their welfare and reduce their chances of adoption. Recent interest in psychedelic-assisted approaches has suggested potential therapeutic applications in ...
Elisa Hernández-Álvarez, Cristina Canino-Quijada, Sira Roiz, Octavio P. Luzardo, Luis Alberto Henríquez-Hernández   +4 more
doaj   +1 more source

Contribution of the Serotonin 5‐HT2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
Psilocin, the active metabolite of psilocybin, ameliorated social avoidance behavior in mice exposed to chronic social defeat stress when administered after, but not before, stress exposure via serotonin 5‐HT2A receptor activation. These findings suggest that psilocin exerts therapeutic, but not preventive, effects on stress‐induced social behavioral ...
Daisuke Ibi, Rika Takaba, Keisuke Yoshida, Ririna Kawase, Hiroko Kitagawa, Momoko Matsushita, Kana Ito, Shoya Uno, Fumiya Nishimura, Shinji Kitagaki, Masayuki Hiramatsu   +10 more
wiley   +1 more source

Development of Japanese Versions of the 4‐Item Mystical Experience Questionnaire and 7‐Item Challenging Experience Questionnaire

Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.
The authorized Japanese versions of the MEQ‐4 and CEQ‐7 were developed in accordance with ISPOR good practice guidelines. These brief scales enable the rapid assessment of mystical and challenging experiences among Japanese speakers. ABSTRACT Introduction Interest in therapeutic applications of psychedelics has recently resurged.
Futaba Umemura, Hiroko Kotajima‐Murakami, Justin C. Strickland, Albert Garcia‐Romeu, Matthew W. Johnson, Kazutaka Ikeda   +5 more
wiley   +1 more source

Extraction and Identification of Clavine and Lysergic Acid Alkaloids from Morning Glories [PDF]

, 1975
Author Institution: Department of Zoology and Microbiology, Ohio UniversityWITTERS, WELDON L. Extraction and identification of clavine and lysergic acid alkaloids from morning glories. Ohio J. Sci.
Witters, Weldon L.
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