Results 1 to 10 of about 4,220 (134)

Clinical Research on Lysergic Acid Diethylamide (LSD) in Psychiatry and Neuroscience [PDF]

open access: yesPharmaceuticals
Lysergic acid diethylamide (LSD) is gaining renewed interest as a potential treatment for anxiety, depression, and alcohol use disorder, with clinical trials reporting significant symptom reductions and long-lasting effects.
Hossein Omidian, Alborz Omidian
doaj   +2 more sources

Identification of 1-Butyl-Lysergic Acid Diethylamide (1B-LSD) in Seized Blotter Paper Using an Integrated Workflow of Analytical Techniques and Chemo-Informatics

open access: yesMolecules, 2020
The rapid dispersion of new psychoactive substances (NPS) presents challenges to customs services and analytical laboratories, which are involved in their detection and characterization.
Emmanouil Tsochatzis   +5 more
doaj   +3 more sources

Lysergic acid diethylamide (LSD) promotes social behaviour through 5-HT2A and ampa in the medial prefrontal cortex (MPFC) [PDF]

open access: yesEuropean Psychiatry, 2021
Introduction Autism Spectrum Disorder and Social Anxiety Disorder are mental illnesses characterized by a dysfunction in social behavior (SB); a phenomenon largely mediated by the medial prefrontal cortex (mPFC). Clinical studies have demonstrated that
A. Markopoulos   +3 more
doaj   +2 more sources

Cytotoxic, genotoxic, and oxidative stress-related effects of lysergic acid diethylamide (LSD) and phencyclidine (PCP) in the human neuroblastoma SH-SY5Y cell line [PDF]

open access: yesArhiv za Higijenu Rada i Toksikologiju, 2021
Lysergic acid diethylamide (LSD) is a classic hallucinogen, widely abused for decades, while phencyclidine (PCP) has increased in popularity in recent years, especially among the adolescents.
Jurič Andreja   +8 more
doaj   +2 more sources

Characterizing non-hallucinogenic psychedelics beyond the head twitch response: phenotypic fingerprinting of lisuride and LSD [PDF]

open access: yesTranslational Psychiatry
The head-twitch response (HTR) is widely used as a preclinical assay for the hallucinogenic potential of compounds, with its utility based on 5HT2AR activation. Here, we examine how the polypharmacological agonists lisuride and lysergic acid diethylamide
Jillian L. King   +6 more
doaj   +2 more sources

Psychedelics: A new era of treatment?

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +1 more source

Understanding the effects of lysergic acid diethylamide and the importance of its prevention

open access: yesHealth Sciences Review, 2023
This review is on lysergic acid diethylamide (LSD), which has a halogenic effect and is addictive. Up to now, LSD has been used for pleasure-inducing or spiritual purposes. Since it is soluble in water, it can be administered in different forms.
Burak Okumuş   +2 more
doaj   +1 more source

Suicidal cut‐throat wound during LSD intoxication

open access: yesClinical Case Reports, 2021
Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug affecting the mood and perception of an individual. Although LSD‐induced self‐inflicted cut‐throat wounds and self‐harm injuries are extremely rarely reported behaviors, some reports are ...
Palash Kumar Bose   +3 more
doaj   +1 more source

LSD degrades hippocampal spatial representations and suppresses hippocampal-visual cortical interactions

open access: yesCell Reports, 2021
Summary: Lysergic acid diethylamide (LSD) produces hallucinations, which are perceptions uncoupled from the external environment. How LSD alters neuronal activities in vivo that underlie abnormal perceptions is unknown.
Carli Domenico   +3 more
doaj   +1 more source

After more than sixty years we are still unclear whether LSD has a place in clinical psychiatry

open access: yesResearch in Psychotherapy, 2020
Dear Editor, The use of the psychedelic Lysergic Acid Diethylamide (LSD) has again provoked scientific debate over its efficacy and safety. In the 1950s-1960s LSD was used in psychotherapy for treating depression, anxiety related to terminal cancer ...
arthur saniotis
doaj   +1 more source

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