Results 21 to 30 of about 12,621 (244)

Suicidal cut‐throat wound during LSD intoxication

open access: yesClinical Case Reports, 2021
Lysergic acid diethylamide (LSD) is a potent hallucinogenic drug affecting the mood and perception of an individual. Although LSD‐induced self‐inflicted cut‐throat wounds and self‐harm injuries are extremely rarely reported behaviors, some reports are ...
Palash Kumar Bose   +3 more
doaj   +1 more source

LSD degrades hippocampal spatial representations and suppresses hippocampal-visual cortical interactions

open access: yesCell Reports, 2021
Summary: Lysergic acid diethylamide (LSD) produces hallucinations, which are perceptions uncoupled from the external environment. How LSD alters neuronal activities in vivo that underlie abnormal perceptions is unknown.
Carli Domenico   +3 more
doaj   +1 more source

After more than sixty years we are still unclear whether LSD has a place in clinical psychiatry

open access: yesResearch in Psychotherapy, 2020
Dear Editor, The use of the psychedelic Lysergic Acid Diethylamide (LSD) has again provoked scientific debate over its efficacy and safety. In the 1950s-1960s LSD was used in psychotherapy for treating depression, anxiety related to terminal cancer ...
arthur saniotis
doaj   +1 more source

Psycholytic Therapy Using LSD: a Realist Review. [PDF]

open access: yesBrain Behav
Psycholytic therapy using d‐lysergic acid diethylamide (LSD) appears safe and therapeutically effective when delivered with strong therapeutic trust, extensive preparation, and more than ten sessions. Flexible, relationally focused methods and creative integration work are associated with better outcomes and reduced adverse events.
Grime H, Drini E.
europepmc   +2 more sources

A non-hallucinogenic LSD analog with therapeutic potential for mood disorders

open access: yesCell Reports, 2023
Summary: Hallucinations limit widespread therapeutic use of psychedelics as rapidly acting antidepressants. Here we profiled the non-hallucinogenic lysergic acid diethylamide (LSD) analog 2-bromo-LSD (2-Br-LSD) at more than 33 aminergic G protein-coupled
Vern Lewis   +18 more
doaj   +1 more source

Biological studies of clavine alkaloids targeting CNS receptors

open access: yesFrontiers in Psychiatry, 2023
In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in spite of their broad occurrence in nature and their well-established ...
Nikhil R. Tasker   +2 more
doaj   +1 more source

Lysergic Acid Diethylamide, Psilocybin and Dimethyltryptamine in Depression Treatment: A Systematic Review

open access: yesPharmaceuticals, 2021
Despite many different kinds of substances available for depression treatment, depression itself still appears to be a clinical challenge. Recently, formerly illicit substances came to scientists’ attention, including lysergic acid diethylamide (LSD ...
Gniewko Więckiewicz   +4 more
doaj   +1 more source

Transcriptomics-informed large-scale cortical model captures topography of pharmacological neuroimaging effects of LSD

open access: yeseLife, 2021
Psychoactive drugs can transiently perturb brain physiology while preserving brain structure. The role of physiological state in shaping neural function can therefore be investigated through neuroimaging of pharmacologically induced effects.
Joshua B Burt   +7 more
doaj   +1 more source

LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain

open access: yesSouth African Medical Journal, 2023
Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic pain often fails to meet the needs
J Van Der Walt, R Parker
doaj   +1 more source

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