Results 51 to 60 of about 2,690,172 (163)

Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Optic nerve hypoplasia and septo‐optic‐pituitary dysplasia. Abstract The presence of a small optic disc on funduscopy is prerequisite for the diagnosis of optic nerve hypoplasia (ONH). Visual acuity may be normal. However, amblyopia can occur in ONH. A relative afferent pupillary light defect indicates unilateral or asymmetrical ONH.
Michael S. Salman
wiley   +1 more source

Effect of lysergic acid diethylamide and its brom analogue on arterial hypertension in the rat

open access: yes, 1961
Subcutaneous administration of d-lysergic acid diethylamide (LSD) or 2-brom- d-lysergic acid diethylamide (BOL) markedly lowered the blood pressure of renal hypertensive rats.
George H. Fried   +3 more
core   +1 more source

Over 30 million psychedelic users in the United States [v1; ref status: indexed, http://f1000r.es/w8]

open access: yesF1000Research, 2013
We estimated lifetime prevalence of psychedelic use (lysergic acid diethylamide (LSD), psilocybin (magic mushrooms), mescaline, and peyote) by age category using data from a 2010 US population survey of 57,873 individuals aged 12 years and older.
Teri S Krebs, Pål-Ørjan Johansen
doaj   +1 more source

Persisting Reductions in Cannabis, Opioid, and Stimulant Misuse After Naturalistic Psychedelic Use: An Online Survey

open access: yesFrontiers in Psychiatry, 2020
BackgroundObservational data and preliminary studies suggest serotonin 2A agonist psychedelics may hold potential in treating a variety of substance use disorders (SUDs), including opioid use disorder (OUD).AimsThe study aim was to describe and analyze ...
Albert Garcia-Romeu   +7 more
doaj   +1 more source

Same‐night PrEP in community care: The Nightcafé model for male and transgender sex workers

open access: yesHIV Medicine, EarlyView.
Abstract Introduction Despite high risk of HIV infection, uptake of pre‐exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcafé programme addresses this gap by offering low‐threshold PrEP provision in a community‐centred setting ...
Elena Heizmann   +9 more
wiley   +1 more source

Lysergic acid diethylamide (LSD) [PDF]

open access: yes, 2019
Lysergic acid diethylamide (LSD) is a drug known for its hallucinogenic properties especially at high doses and in recent years has been used as a pharmacological model to study the neurological substrate of psychosis, the effect of antipsychotics, and ...
Kehayova, Gabriela; Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University of Varna, Bulgaria   +2 more
core   +2 more sources

DataSheet1_Construction of an efficient Claviceps paspali cell factory for lysergic acid production.docx

open access: yes, 2023
Lysergic acid (LA) is the key precursor of ergot alkaloids, and its derivatives have been used extensively for the treatment of neurological disorders. However, the poor fermentation efficiency limited its industrial application.
Siyu Du (14501138)   +9 more
core   +1 more source

Natural Ergot Alkaloids in Ocular Pharmacotherapy: Known Molecules for Novel Nanoparticle-Based Delivery Systems

open access: yesBiomolecules, 2020
Several pharmacological properties are attributed to ergot alkaloids as a result of their antibacterial, antiproliferative, and antioxidant effects.
Iara Baldim   +12 more
doaj   +1 more source

Essential Oils of Argyreia capitiformis (Poir.) Ooststr. and Argyreia nasirii D.F. Austin: Chemical Analysis and Biological Activities

open access: yesChemistry &Biodiversity, Volume 23, Issue 11, November 2026.
Essential oils of Argyreia capitiformis and Argyreia nasirii display clearly distinct chemical and biological profiles. A. capitiformis is dominated by sesquiterpene hydrocarbons, particularly (E)‐caryophyllene, and shows cytotoxicity against HepG2, SK‐LU‐1, and MCF‐7 cells. In contrast, A.
Tran Thi Ngoc Hanh   +7 more
wiley   +1 more source

Prevalence of novel psychoactive substances in selected clinical urine specimens submitted for drug monitoring

open access: yesJournal of Forensic Sciences, Volume 71, Issue 6, Page 2889-2899, November 2026.
Abstract Novel psychoactive substances (NPS) are compounds emerging as alternatives to more established drugs of abuse. They are constantly changing and being modified, which makes their detection difficult. The study objective was to determine the prevalence of NPS in selected clinical specimens. Deidentified urine specimen remnants were analyzed that
Jillian R. Neifeld   +2 more
wiley   +1 more source

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