Results 1 to 10 of about 2,729,303 (155)
Contribution of a novel gene to lysergic acid amide synthesis in Metarhizium brunneum [PDF]
BMC Research Notes, 2022 Objective The fungus Metarhizium brunneum produces ergot alkaloids of the lysergic acid amide class, most abundantly lysergic acid α-hydroxyethylamide (LAH). Genes for making ergot alkaloids are clustered in the genomes of producers. Gene clusters of LAH-
Kelcie N. Britton +4 more
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A single lysergyl peptide synthetase assembles lysergic acid amides in Aspergillus species. [PDF]
PLoS ONEThe agriculturally and pharmaceutically important lysergic acid amides ergonovine and lysergic acid α-hydroxyethylamide (LAH) are synthesized from a lysergyl-alanine precursor.
Samantha J Fabian +3 more
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A Baeyer-Villiger Monooxygenase Gene Involved in the Synthesis of Lysergic Acid Amides Affects the Interaction of the Fungus Metarhizium brunneum With Insects. [PDF]
Applied and Environmental Microbiology, 2021 Fungi in the genus Metarhizium are important plant root symbionts and insect pathogens. They are formulated commercially to protect plants from insect pests.
Daniel Panaccione +2 more
exaly +5 more sources
Gene Editing of the Thioester Reductase Step in the Biosynthesis of Lysergic Acid Amides [PDF]
PLoS ONEErgot alkaloids derived from lysergic acid are important in agriculture, as food and feed contaminants, and in medicine, as the foundation of several pharmaceuticals. The fungus Metarhizium brunneum makes several lysergic acid amides, with lysergic acid α-hydroxyethylamide (LAH) being ...
Daniel Panaccione, Jessica L Fuss
exaly +4 more sources
Chemical and Pharmaceutical Bulletin, 1979 Microbial transformation of the amide congeners of lysergic acid diethylamide (LSD) by Streptomyces roseochromogenes was examined. Derivatives having no methylene group at the (ω-1) position of the amine alkyl chain of the amide function, lysergic acid dimethylamide (LDM) and lysergic acid diallylamide (LDA), were oxidized at the α-position of the ...
ISHII, HISASHI +3 more
exaly +3 more sources
Pharmacy (Basel, Switzerland)Objective: To systematically review the scientific literature on lysergic acid amide (LSA), focusing on its physical, neurobiological, and social effects, as well as its potential risks and therapeutic uses. Methods: A systematic review was conducted across PubMed, Google Scholar, and Web of Science up to December 2023, using keywords such as “ergine,”
João Maurício Castaldelli-Maia +2 more
exaly +3 more sources
UPDATED REVIEW ON EXTRACTION, ISOLATION AND QUANTITATIVE ESTIMATION OF ERGOT ALKALOIDS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 2022 Ergot Alkaloids are potent α-blockers that cause direct smooth muscle contraction. They are products of fungi in the genus Claviceps. The most prominent member of this group is Claviceps purpurea (rye ergot fungus).
B. Ramya Kuber, P. Sowmya, I. Theja
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Survival and development of potato psyllid (Hemiptera: Triozidae) on Convolvulaceae: Effects of a plant-fungus symbiosis (Periglandula). [PDF]
PLoS ONE, 2018 Plant species in the family Solanaceae are the usual hosts of potato psyllid, Bactericera cockerelli (Šulc) (Hemiptera: Psylloidea: Triozidae). However, the psyllid has also been shown to develop on some species of Convolvulaceae (bindweeds and morning ...
Navneet Kaur +6 more
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Distinction of Some Dialkyl Amides of Lysergic and iso-Lysergic Acids from LSD
Journal of AOAC INTERNATIONAL, 1973 Abstract The 10 lysergic and iso-lysergic acid amides described are N,N-dimethyl-, N,N-diethyl-, N-methyl-N-propyl, N-ethyl-N-propyl, and N,N-dipropyl-. Their ultraviolet spectra are insufficiently different for distinction. Mass spectra do not readily differentiate between isomers.
K, Bailey, D, Verner, D, Legault
openaire +2 more sources
Biosynthetic Pathways of Ergot Alkaloids
Toxins, 2014 Ergot alkaloids are nitrogen-containing natural products belonging to indole alkaloids. The best known producers are fungi of the phylum Ascomycota, e.g., Claviceps, Epichloë, Penicillium and Aspergillus species.
Nina Gerhards +3 more
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