Results 31 to 40 of about 2,690,172 (163)

Understanding the effects of lysergic acid diethylamide and the importance of its prevention

Health Sciences Review, 2023
This review is on lysergic acid diethylamide (LSD), which has a halogenic effect and is addictive. Up to now, LSD has been used for pleasure-inducing or spiritual purposes. Since it is soluble in water, it can be administered in different forms.
Burak Okumuş, Ahmet Metin, İ. Afşin Kariper   +2 more
doaj   +1 more source

BMC Microbiology / Rhodococcus erythropolis MTHt3 biotransforms ergopeptines to lysergic acid [PDF]

, 2015
Background: Ergopeptines are a predominant class of ergot alkaloids produced by tall fescue grass endophyte Neotyphodium coenophialum or cereal pathogen Claviceps purpurea.
Kunz-Vekiru, Elisavet, Schatzmayr, Gerd, Schwartz-Zimmermann, Heidi Elisabeth, Gerd Schatzmayr, Michaela Thamhesl, Wolfgang Kneifel, Wulf-Dieter Moll, Moll, Wulf-Dieter, Apfelthaler, Elisabeth, Thamhesl, Michaela, Elisabeth Apfelthaler, Krska, Rudolf, Heidi Elisabeth Schwartz-Zimmermann, Kneifel, Wolfgang, Elisavet Kunz-Vekiru, Rudolf Krska   +15 more
core   +1 more source

SYNTHESIS OF 6-SUBSTITUTED NICOTINIC ACID DERIVATIVES AS LYSERGIC ACID ANALOGS.

, 1963
SYNTHESIS OF 6-SUBSTITUTED NICOTINIC ACID DERIVATIVES AS LYSERGIC ACID ...
JACOB. LEHRFELD (7956074)
core   +2 more sources

Analysis of Ergot Alkaloids

Toxins, 2015
The principles and application of established and newer methods for the quantitative and semi-quantitative determination of ergot alkaloids in food, feed, plant materials and animal tissues are reviewed.
Colin Crews
doaj   +1 more source

A Major Facilitator Superfamily Transporter Contributes to Ergot Alkaloid Accumulation but Not Secretion in Aspergillus leporis

Applied Microbiology
Ergot alkaloids are fungal natural products with important roles in agriculture and medicine. We used heterologous expression and gene knockout approaches to investigate potential roles for the product of a major facilitator superfamily transporter gene (
Abigail M. Jones, Kyle A. Davis, Daniel G. Panaccione   +2 more
doaj   +1 more source

Psilocybin sex-dependently reduces alcohol consumption in C57BL/6J mice

Frontiers in Pharmacology, 2023
The classical psychedelic psilocybin is of interest as a treatment for alcohol use disorder (AUD). This study investigated the effects of psilocybin on voluntary ethanol consumption in adult male and female C57BL/6J mice administered saline or psilocybin
Kenneth Alper, Kenneth Alper, Janelle Cange, Ria Sah, Deanna Schreiber-Gregory, Henry Sershen, Henry Sershen, K. Yaragudri Vinod, K. Yaragudri Vinod, K. Yaragudri Vinod   +9 more
doaj   +1 more source

Asymmetric Synthesis of Lysergic Acid via an Intramolecular (3+2) Dipolar Cycloaddition/Ring-Expansion Sequence

, 2021
An effective, potentially scalable asymmetric synthesis of lysergic acid, a core component of the ergot alkaloid family, is reported. The synthesis features the strategic combination of an intramolecular azomethine ylide cycloaddition and Cossy–Charette ...
Philip Garner (1831117), Philip Garner, Upendra Rathnayake, Upendra Rathnayake (6611201)   +3 more
core   +1 more source

Total Synthesis of (±)-Lysergic Acid, Lysergol, and Isolysergol by Palladium-Catalyzed Domino Cyclization of Amino Allenes Bearing a Bromoindolyl Group

, 2016
Total Synthesis of (±)-Lysergic Acid, Lysergol, and Isolysergol by Palladium-Catalyzed Domino Cyclization of Amino Allenes Bearing a Bromoindolyl ...
Hiroaki Ohno (1457971), Shinya Oishi (164565), Nobutaka Fujii (164590), Shinsuke Inuki (1944640)   +3 more
core   +2 more sources

Biochemical and Genetic Characterization of Ergot Alkaloid Biosynthesis in Aspergillus aspearensis

Toxins
Ergot alkaloids derived from lysergic acid have impacted humankind significantly as toxins in agriculture and as the foundations of several pharmaceuticals.
Jessica L. Fuss, Daniel G. Panaccione
doaj   +1 more source

Acute effects of lysergic acid diethylamide (LSD) on resting brain function

Swiss Medical Weekly, 2019
Lysergic acid diethylamide (LSD) is a potent hallucinogenic substance that was extensively investigated by psychiatrists during the 1950s and 1960s.
Felix Müller, Stefan Borgwardt
doaj   +1 more source