Results 21 to 30 of about 2,690,172 (163)

Total Synthesis of Lysergic Acid

open access: yes, 2016
A total synthesis of lysergic acid was accomplished. Key features of our synthesis include stereoselective construction of the stereogenic centers at the allylic positions by using the Evans aldol reaction, and a sequential process with a ring-closing ...
Tohru Fukuyama (1508317)   +2 more
core   +3 more sources

Enantioefficient Synthesis of α-Ergocryptine:  First Direct Synthesis of (+)-Lysergic Acid

open access: yes, 2016
The first direct synthesis of (+)-lysergic acid (2a) suitable for scale-up has been achieved by the following reaction sequence. Bromoketones 4d or 4g were allowed to react with amine 5 followed by deprotection, and the resulting diketone 6c was ...
István Moldvai (2640835)   +5 more
core   +4 more sources

Lysergic Acid Diethylamide, Psilocybin and Dimethyltryptamine in Depression Treatment: A Systematic Review

open access: yesPharmaceuticals, 2021
Despite many different kinds of substances available for depression treatment, depression itself still appears to be a clinical challenge. Recently, formerly illicit substances came to scientists’ attention, including lysergic acid diethylamide (LSD ...
Gniewko Więckiewicz   +4 more
doaj   +1 more source

LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain

open access: yesSouth African Medical Journal, 2023
Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic pain often fails to meet the needs
J Van Der Walt, R Parker
doaj   +1 more source

Pengalaman Anak Jalanan Usia Remaja Dalam Perilaku Inhalasi Lysergic Acid Diethylamide

open access: yesJurnal Ilmu Keperawatan Anak, 2019
Seorang anak bisa menjadi anak jalanan tentu mempunyai hal yang melatarbelakangi dalam kehidupannya. Sehingga anak jalanan sangat rentan untuk terjerumus kedalam perilaku menyimpang salah satunya adalah perilaku inhalasi zat adiktif seperti Lysergic Acid
Chatarina Suryaningsih   +1 more
doaj   +1 more source

Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020. [PDF]

open access: yesJ Psychopharmacol, 2023
Supplemental material, sj-docx-1-jop-10.1177_02698811231158245 for Investigation of self-treatment with lysergic acid diethylamide and psilocybin mushrooms: Findings from the Global Drug Survey 2020 by Emma I Kopra, Jason A Ferris, Adam R Winstock, Kim ...
Kopra EI   +5 more
europepmc   +2 more sources

Comparative Ergot Alkaloid Elaboration by Selected Plectenchymatic Mycelia of Claviceps purpurea through Sequential Cycles of Axenic Culture and Plant Parasitism

open access: yesBiology, 2020
Ergot alkaloids have an established place in plant pathology and toxicology. As pharmaceuticals, their sourcing is via natural or managed agricultural occurrence of sclerotia of Claviceps purpurea (Fr.) Tul.
Peter Mantle
doaj   +1 more source

Six-Step Synthesis of (±)-Lysergic Acid

open access: yes, 2023
This article describes a concise synthesis of lysergic acid from simple aromatic precursors. The successful strategy relies on the coupling, dearomatization, and cyclization of a halopyridine with a 4-haloindole derivative in 6 total synthetic steps from
Ryan C. Harbit (14521878)   +5 more
core   +1 more source

Biological studies of clavine alkaloids targeting CNS receptors

open access: yesFrontiers in Psychiatry, 2023
In contrast to well established psychedelics such as lysergic acid diethylamide (LSD) and psilocybin, ergot alkaloids of the clavine subclass have not been thoroughly investigated, in spite of their broad occurrence in nature and their well-established ...
Nikhil R. Tasker   +2 more
doaj   +1 more source

Psychedelics: A new era of treatment?

open access: yesEuropean Psychiatry, 2021
Introduction Psychedelics - including LSD (lysergic acid diethylamide), psilocybin, DMT (N, N-dimethyltryptamine), ayahuasca and mescaline - have an ancient history across various civilizations.
S. Torres
doaj   +1 more source

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