Lysergic acid diethylamide (LSD) promotes social behaviour through 5-HT2A and ampa in the medial prefrontal cortex (MPFC) [PDF]
European Psychiatry, 2021 Introduction Autism Spectrum Disorder and Social Anxiety Disorder are mental illnesses characterized by a dysfunction in social behavior (SB); a phenomenon largely mediated by the medial prefrontal cortex (mPFC). Clinical studies have demonstrated that
A. Markopoulos +3 more
doaj +2 more sources
Independent Evolution of a Lysergic Acid Amide in Aspergillus Species [PDF]
Applied and Environmental Microbiology, 2021 Daniel G Panaccione
exaly +2 more sources
ESTRATÉGIAS PARA A SÍNTESE DO ÁCIDO LISÉRGICO
Química Nova, 2021 STRATEGIES FOR THE SYNTHESIS OF LYSERGIC ACID. (+)-Lysergic acid [(+)-1] is a precursor of several substances with well-established pharmacological properties, including some drugs approved and commercialized around the world. Thus, the importance of (+)-
Tamiris R. C. Silva, Cristiano Raminelli
doaj +1 more source
A Baeyer-Villiger Monooxygenase Gene Involved in the Synthesis of Lysergic Acid Amides Affects the Interaction of the Fungus Metarhizium brunneum with Insects [PDF]
Applied and Environmental Microbiology, 2021 Daniel G Panaccione
exaly +2 more sources
A New Synthesis of Lysergic Acid [PDF]
Organic Letters, 2003 [reaction: see text] (+/-)-Lysergic acid has been synthesized via an economical 8-step route from 4-bromoindole and isocinchomeronic acid without the need to protect the indole during the synthesis. Initial efforts to form the simpler 3-acylindole derivatives first and then cyclize these were unsuccessful in the cyclization step.
James B, Hendrickson, Jian, Wang
openaire +2 more sources
Improving Ergometrine Production by easO and easP Knockout in Claviceps paspali
Fermentation, 2022 Ergometrine is widely used for the treatment of excessive postpartum uterine bleeding. Claviceps paspali is a common species for industrial production of ergometrine, which is often accompanied by lysergic acid α-hydroxyethylamide (LAH) and lysergic acid
Yun-Ming Qiao +6 more
doaj +1 more source
European Psychiatry, 2023 Introduction Zebrafish (Danio rerio) has evolved over the years as a preferred organism due to its vast repertoire in research fields that mimic a targeted phenotype, particularly behavioral typologies and specific attributes comparable to murine models
I. B. Nita +5 more
doaj +1 more source
Total Synthesis of Lysergic Acid [PDF]
Organic Letters, 2013 A total synthesis of lysergic acid was accomplished. Key features of our synthesis include stereoselective construction of the stereogenic centers at the allylic positions by using the Evans aldol reaction, and a sequential process with a ring-closing metathesis and an intramolecular Heck reaction to construct the C and D rings.
Satoshi, Umezaki +2 more
openaire +4 more sources
Perceived Risk of Trying Lysergic Acid Diethylamide in the United States from 2015 to 2019: Are Americans Assessing Lysergic Acid Diethylamide's Risk Profile More Favorably? [PDF]
Psychedelic Med (New Rochelle)Jeremy Weleff +2 more
exaly +2 more sources
Drugs in therapy. LSD, MDMA, marijuana, psilocybin, designer drugs and its potential in modern medicine. [PDF]
Farmacja Polska, 2020 Research on using drugs in medicine was almost completely stopped and delegalized in 1971, by Convention on Psychotropic Substances. Most of studies carried out before 1971 were methodologically inappropriate according to current research methodologies ...
Agata Tadeja
doaj +1 more source