Results 91 to 100 of about 12,110 (254)
Receptor interaction profiles of novel N-2-methoxybenzyl (NBOMe) derivatives of 2,5-dimethoxy-substituted phenethylamines (2C drugs) [PDF]
, 2015 N-2-methoxybenzyl-phenethylamines (NBOMe drugs) are newly used psychoactive substances with poorly defined pharmacological properties. The aim of the present study was to characterize the receptor binding profiles of a series of NBOMe drugs compared with
Buchy, Danièle +5 more
core +1 more source
Physical attractiveness, drug taking and gender differences
Canadian Journal of Economics/Revue canadienne d'économique, EarlyView.Abstract This study investigates the relationship between adolescent physical attractiveness and drug‐taking behaviour, emphasizing the human capital and “pretty girl” effects on the decision to use drugs. Through the human capital effect, physically attractive adolescents are better positioned to accumulate human capital at a young age compared to ...
Andy Chung, Junsen Zhang
wiley +1 more source
LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice
Frontiers in Pharmacology, 2018 There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use disorder.
Kenneth Alper +8 more
doaj +1 more source
Class A drug abuse: an ophthalmologist's problem? [PDF]
, 2005 [First Paragraph] The 2002/3 British Crime Survey reported that 3% of all 16 to 59 year olds (equating to around one million people) had used a class A drug in the last year.
Firth, A.Y.
core +1 more source
Mass Spectrometry Reviews, Volume 45, Issue 2, Page 392-428, March/April 2026.ABSTRACT In the 1980s, researchers discovered the remarkable ability of electrospray plumes to effectively ionize gas‐phase molecules via secondary ionization. Around 20 years later—coinciding with the ambient mass spectrometry revolution—secondary electrospray ionization (SESI) and extractive electrospray ionization (EESI) coupled to mass spectrometry
Xin Luo +5 more
wiley +1 more source
Molecular determinants of signal transduction in tropomyosin receptor kinases
FEBS Open Bio, Volume 16, Issue 2, Page 252-267, February 2026.Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley +1 more source
ENTHEOGENS, MYSTICISM, AND NEUROSCIENCE
Zygon, 2014 Entheogens or psychedelic drugs such as lysergic acid diethylamide (LSD) and psilocybin are associated with mystical states of experience. Drug laws currently limit research, but important new work is under way at major biomedical research facilities ...
doaj +2 more sources
Clinical Pharmacology in Drug Development, Volume 15, Issue 2, February 2026.Abstract BNC210 is an investigational small molecule selective negative allosteric modulator of the alpha‐7 nicotinic acetylcholine receptor (α7 nAChR). It is an anxiolytic compound with a novel mechanism of action. In a series of Phase 1 clinical trials in healthy volunteers, psychometric test batteries showed that BNC210 did not cause attention ...
Paul Rolan +7 more
wiley +1 more source
Reaction of N,N-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions. [PDF]
, 2018 A large number of clinically used drugs and experimental pharmaceuticals possess the N,N-dimethyltryptamine (DMT) structural core. Previous reports have described the reaction of this motif with dichloromethane (DCM), a common laboratory solvent used ...
Dunlap, Lee E, Olson, David E
core +3 more sources
I Feel I Need to Think about It: A Defence of Affective Moral Enhancement
Bioethics, Volume 40, Issue 2, Page 175-182, February 2026.ABSTRACT Critics of affective moral enhancement generally contend that moral improvement can only be properly achieved through interventions that engage a person's rational faculties. Therefore, they view attempts to achieve moral improvement by targeting emotions as futile at best and detrimental to moral agency at worst.
Pei‐hua Huang
wiley +1 more source