Results 81 to 90 of about 5,934 (217)

Pharmacokinetics and Concentration-Effect Relationship of Oral LSD in Humans [PDF]

, 2021
Background: The pharmacokinetics of oral lysergic acid diethylamide are unknown despite its common recreational use and renewed interest in its use in psychiatric research and practice.
Dolder, Patrick C., Rentsch, Katharina M., Liechti, Matthias E., Schmid, Yasmin, Haschke, Manuel   +4 more
core  

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice

Frontiers in Pharmacology, 2018
There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use disorder.
Kenneth Alper, Kenneth Alper, Bin Dong, Relish Shah, Henry Sershen, Henry Sershen, K. Yaragudri Vinod, K. Yaragudri Vinod, K. Yaragudri Vinod   +8 more
doaj   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, Volume 183, Issue 14, Page 4006-4021, July 2026.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, Volume 183, Issue 14, Page 4022-4047, July 2026.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Return of the lysergamides. Part V: Analytical and behavioural characterization of 1-butanoyl-d-lysergic acid diethylamide (1B-LSD) [PDF]

, 2019
The psychedelic properties of lysergic acid diethylamide (LSD) have captured the imagination of researchers for many years and its rediscovery as an important research tool is evidenced by its clinical use within neuroscientific and therapeutic settings.
Folker Westphal, Alexander Stratford, Simon D. Brandt, Kavanagh, PV, Simon P. Elliott, Halberstadt, AL, Elliott, SP, Jason Wallach, Stratford, A, Brandt, SD, Westphal, F, Dowling, G, Wallach, J, Geraldine Dowling, Adam L. Halberstadt, Pierce V. Kavanagh   +15 more
core   +1 more source

sj-docx-1-jop-10.1177_02698811211055855 – Supplemental material for Perceptions of safety, subjective effects, and beliefs about the clinical utility of lysergic acid diethylamide in healthy participants within a novel intervention paradigm: Qualitative results from a proof-of-concept study

, 2022
Supplemental material, sj-docx-1-jop-10.1177_02698811211055855 for Perceptions of safety, subjective effects, and beliefs about the clinical utility of lysergic acid diethylamide in healthy participants within a novel intervention paradigm: Qualitative ...
David Luke (11301588), Peter S Hendricks (9387032), Heith Copes (9387020), Luke TJ Williams (12211851), Shlomi Raz (12211860), Neiloufar Family (12211848)   +5 more
core   +1 more source

ENTHEOGENS, MYSTICISM, AND NEUROSCIENCE

Zygon, 2014
Entheogens or psychedelic drugs such as lysergic acid diethylamide (LSD) and psilocybin are associated with mystical states of experience. Drug laws currently limit research, but important new work is under way at major biomedical research facilities ...
doaj   +2 more sources

Health, Social and Recidivism Outcomes Among People Who Have Been Incarcerated in New South Wales, Australia: Study Protocol and Cohort Profile for the Prison Outcomes STudy (POST)

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction We have been funded to examine post‐incarceration health and social outcomes for all people incarcerated in New South Wales, Australia, 2000–2022; assess treatment and services for drug dependence and serious mental illness; and project the impact of expanding intervention coverage. We will use a linked cohort, the Prison Outcomes
Louisa Degenhardt, Michael Farrell, Michael Doyle, Jack Stone, Chrianna Bharat, Matt Hickman, Marianne Martinello, Don Weatherburn, Kimberlie Dean, Joe Coyte, Christel Macdonald, Mary Ellen Harrod, Luke Grant, Gloria Larman, Peter Vickerman, Colette McGrath, Peter Thompson, Alison Churchill, Greg Dore, Thomas Santo Jr   +19 more
wiley   +1 more source

Personalised Perception: The Effect of Personality on the Sensory Effects of Psychedelics

Drug and Alcohol Review, Volume 45, Issue 5, July 2026.
ABSTRACT Introduction Psychedelics induce a wide range of sensory distortions and hallucinations (henceforth ‘distortions’). Yet, little is known about factors that influence the occurrence of certain distortions. Extra‐pharmacological variables including personality traits have been found to correlate with the occurrence of different subjective ...
Alexander Boardman, Jai Whelan, Ryan D. Ward   +2 more
wiley   +1 more source

Acute effects of lysergic acid diethylamide in healthy subjects [PDF]

, 2015
After no research in humans for >40 years, there is renewed interest in using lysergic acid diethylamide (LSD) in clinical psychiatric research and practice.
Vollenweider, Franz X, Liechti, M.E., Vollenweider, F.X., Liechti, Matthias E, Grouzmann, E., Brenneisen, R., Brenneisen, Rudolf, Preller, Katrin H, Schmid, Yasmin, Enzler, Florian, Gasser, P., Preller, Katrin H., Grouzmann, Eric, Müller, F., Schmid, Y., Borgwardt, S., Borgwardt, Stefan, Vollenweider, Franz X., Müller, Felix, Preller, K.H., Liechti, Matthias E., Gasser, Peter, Enzler, F.   +22 more
core   +1 more source