Reversible cerebral vasoconstriction syndrome: A narrative review
Abstract Objectives/Background This review summarizes current insights into Reversible cerebral vasoconstriction syndrome (RCVS) diagnosis, management, and outcomes. RCVS is a cerebrovascular disorder characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months ...
Ícaro Araújo de Sousa +7 more
wiley +1 more source
Reaction of N,N-Dimethyltryptamine with Dichloromethane Under Common Experimental Conditions. [PDF]
A large number of clinically used drugs and experimental pharmaceuticals possess the N,N-dimethyltryptamine (DMT) structural core. Previous reports have described the reaction of this motif with dichloromethane (DCM), a common laboratory solvent used ...
Dunlap, Lee E, Olson, David E
core +3 more sources
Objective: This study aims to provide an overview of pharmacological trials that examine the neurocognitive effects of psychedelics among healthy individuals and patients with post-traumatic stress disorder (PTSD) or major depressive disorder (MDD ...
Mario Renato Velit-Salazar +2 more
doaj +1 more source
Profile, effects, and toxicity of novel psychoactive substances: A systematic review of quantitative studies [PDF]
OBJECTIVE: To investigate the profile, effects, and toxicity of novel psychoactive substances (NPS). METHODS: A systematic literature review was conducted between May 2015 and February 2016 and included 19 databases.
Antonowicz +35 more
core +2 more sources
Therapeutic Potential of Psychedelic Compounds for Substance Use Disorders
Psychedelics have recently (re)emerged as therapeutics of high potential for multiple mental health conditions, including substance use disorders (SUDs).
Tamara Valdez +4 more
doaj +1 more source
Safety pharmacology of acute MDMA administration in healthy subjects [PDF]
3,4-Methylenedioxymethamphetamine (MDMA; ecstasy) is being investigated in MDMA-assisted psychotherapy. The present study characterized the safety pharmacology of single-dose administrations of MDMA (75 or 125 mg) using data from nine double-blind ...
Liechti, Matthias E., Vizeli, Patrick
core +1 more source
Psychedelics as a potential treatment for tobacco use disorder: a systematic review
Introduction Despite considerable efforts, tobacco use disorder persists as a significant public health issue. The effectiveness of current smoking cessation therapies is limited, leading to a growing interest in alternative treatment approaches such as ...
S. K. Spoelstra +3 more
doaj +1 more source
Treatment of neuropathic pain with repeated low-dose MDMA: a case report
A 64-year-old male patient who suffered from traumatic life experiences and neuropathic pain after oncological chemotherapy was treated with medium to high doses of lysergic acid diethylamide (LSD) and high doses and microdoses of ...
Peter Gasser +2 more
doaj +1 more source
Club drugs: Um Novo Perfil de Abuso de Substâncias em Adolescentes e Jovens Adultos.
Club drugs are the following substances: Methylenedioxymethamphetamine (MDMA); Methamphetamine; Lysergic Acid Diethylamide (LSD); Ketamine; Gamma-hydroxybutyrate (GHB) and Flunitrazepam.
Diogo Frasquilho Guerreiro +4 more
doaj +1 more source
The versatile binding landscape of the TAAR1 pocket for LSD and other antipsychotic drug molecules
Summary: Increasing global concerns about psychoactive substance addiction and psychotic disorders highlight the need for comprehensive research into the structure-function relationship governing ligand recognition between these substances and their ...
Kexin Jiang +8 more
doaj +1 more source

