Results 61 to 70 of about 12,110 (254)

Incidents of sudden death during restraint of agitated individuals in Sweden between 1992 and 2024

Journal of Forensic Sciences, EarlyView.
Abstract Restraint‐related sudden deaths in agitated individuals raise complex questions at the intersection of medicine and law. Hyperactive delirium with extreme agitation as well as positional asphyxia due to restraint have been proposed to account for these deaths. However, the exact physiological mechanisms responsible and to what extent restraint
Alexander Tyr, Erik Lindeman, Fredrik Tamsen, Ingemar Thiblin, Brita Zilg   +4 more
wiley   +1 more source

Evaluation of 1cp-LSD for Enhancing Welfare in Shelter Dogs: A Randomized Blind Trial with Ethological Intervention

Veterinary Sciences
Shelter environments frequently expose dogs to chronic stress and anxiety, which can compromise their welfare and reduce their chances of adoption. Recent interest in psychedelic-assisted approaches has suggested potential therapeutic applications in ...
Elisa Hernández-Álvarez, Cristina Canino-Quijada, Sira Roiz, Octavio P. Luzardo, Luis Alberto Henríquez-Hernández   +4 more
doaj   +1 more source

Alterations of consciousness and mystical-type experiences after acute LSD in humans [PDF]

, 2016
Lysergic acid diethylamide (LSD) is used recreationally and in clinical research. Acute mystical-type experiences that are acutely induced by hallucinogens are thought to contribute to their potential therapeutic effects.
Dolder, Patrick C., Liechti, Matthias E., Schmid, Yasmin   +2 more
core   +2 more sources

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Pathological Delta Oscillations in Hallucinogen Persisting Perception Disorder: A Case Report

Frontiers in Psychiatry, 2022
BackgroundHallucinogen persisting perception disorder (HPPD) is characterized by spontaneous recurrence of visual hallucinations or disturbances after previous consumption of hallucinogens, such as lysergic acid diethylamide (LSD).
David Haslacher, Nikolina Novkovic, Maria Buthut, Andreas Heinz, Surjo R. Soekadar   +4 more
doaj   +1 more source

Semantic activation in LSD: evidence from picture naming [PDF]

, 2016
Lysergic acid diethylamide (LSD) is a classic psychedelic drug that alters cognition in a characteristic way. It has been suggested that psychedelics expand the breadth of cognition via actions on the central nervous system.
Bolstridge, M, Carhart-Harris, RL, Family, N, Kaelen, M, Nutt, DJ, Vigliocco, G, Vinson, D   +6 more
core   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Polypharmacy among anabolic-androgenic steroid users: A descriptive metasynthesis [PDF]

, 2015
Background: As far as we are aware, no previous systematic review and synthesis of the qualitative/descriptive literature on polypharmacy in anabolic-androgenic steroid(s) (AAS) users has been published. Method: We systematically reviewed and synthesized
AJ Gruber, AJ Gruber, AJ Gruber, AJ McBride, AJ Viera, Astrid Bjørnebekk, B Hegazy, B Larance, C Ahlgrim, C Wilson-Fearon, Cecilie Schou Andreassen, CN Schäfer, CS Cornford, D Hoff, D Moher, D Moher, D Sagoe, D Sagoe, DA Malone Jr, DL Katz, Dominic Sagoe, E Chahla, E Pappa, F Klötz, G Kanayama, G Kanayama, G Kanayama, G McKillop, GS Goldfield, H Angoorani, H Geyer, HB Moss, HB Moss, HG Pope Jr, HG Pope Jr, IBM Corp, J Bilard, JA Smith, JD Wines, Jim McVeigh, JR Hoffman, K Skårberg, K Skårberg, K Skårberg, KA Clauson, L Degenhardt, L Lundholm, LJ Silvester, M Chandler, M Dunn, M Evans-Brown, Marie-Stella Essilfie, MJ Evans-Brown, N Gårevik, P Korkia, P Korkia, P Lenehan, PJ Fudala, PJ Perry, PJ Perry, R Davies, R Peters, R Shaw, RH Strauss, RP Kusserow, RT Dawson, S Darke, SM Filiault, Ståle Pallesen, T Dodge, T Hildebrandt, TA Pagonis, V Tallon, VD Hope, W Rashid   +74 more
core   +2 more sources

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source