Results 71 to 80 of about 4,220 (134)

Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline. [PDF]

Neuropsychopharmacology, 2022
De Gregorio D, Inserra A, Enns JP, Markopoulos A, Pileggi M, El Rahimy Y, Lopez-Canul M, Comai S, Gobbi G.   +8 more
europepmc   +1 more source

Therapeutic Potential of Psychedelic Compounds for Substance Use Disorders

Pharmaceuticals
Psychedelics have recently (re)emerged as therapeutics of high potential for multiple mental health conditions, including substance use disorders (SUDs).
Tamara Valdez, Valbhi Patel, Nattaphone Senesombath, Zayd Hatahet-Donovan, Mary Hornick   +4 more
doaj   +1 more source

Repeated microdoses of LSD do not alter anxiety or boldness in zebrafish

Scientific Reports
The therapeutic use of lysergic acid diethylamide (LSD) has resurfaced in the last decade, prompting further scientific investigation into its effectiveness in many animal models.
Ethan V. Hagen, Melike Schalomon, Yanbo Zhang, Trevor J. Hamilton   +3 more
doaj   +1 more source

LSD reconfigures cortical dynamics through faster brain rhythms and increased fractal dimension

Communications Biology
Lysergic acid diethylamide (LSD) profoundly alters conscious experience, yet the electrophysiological mechanisms by which it reshapes neural dynamics remain incompletely understood.
Venkatesh Subramani, Timothy Nest, Annalisa Pascarella, Jérémy Brunel, Yorguin José Mantilla Ramos, Yann Harel, Suresh Muthukumaraswamy, Robin Carhart-Harris, Giulia Lioi, Nicolas Farrugia, Karim Jerbi   +10 more
doaj   +1 more source

Lysergic acid diethylamide-derived excitatory/inhibitory ratio change enhances global synchrony in functional brain dynamics.

PLoS Computational Biology
Lysergic acid diethylamide (LSD) has shown remarkable potential in modulating brain functional organization and dynamics. However, the exact mechanisms underlying its effects remain unclear.
Lingyu Zhang, Weiyang Shi, Ziyang Zhao, Zhichao Wang, Congying Chu, Bokai Zhao, Jiaqi Zhang, Qianhui Liu, Yueheng Lan, Tianzi Jiang   +9 more
doaj   +1 more source

Contextual and experiential aspects of the psychedelic experience predicting improvement in subjective wellbeing: results from a Norwegian internet convenience sample

Frontiers in Pharmacology
BackgroundInterest in the therapeutic effects of classical psychedelics has risen recently. However, little epidemiological knowledge exists about the use of classical psychedelics in Scandinavian countries. Additionally, there is a limited understanding
Paula Aarseth Tunstad, Tor-Morten Kvam, Tor-Morten Kvam, Malin V. Uthaug, Malin V. Uthaug, Lowan H. Stewart, Kristoffer A. A. Andersen, Cato Grønnerød   +7 more
doaj   +1 more source

Pharmacological and biotransformation studies of 1-acyl-substituted derivatives of d-lysergic acid diethylamide (LSD). [PDF]

Neuropharmacology, 2020
Halberstadt AL, Chatha M, Klein AK, McCorvy JD, Meyer MR, Wagmann L, Stratford A, Brandt SD.   +7 more
europepmc   +1 more source

Safety, tolerability, pharmacokinetics, and pharmacodynamics of low dose lysergic acid diethylamide (LSD) in healthy older volunteers. [PDF]

Psychopharmacology (Berl), 2020
Family N, Maillet EL, Williams LTJ, Krediet E, Carhart-Harris RL, Williams TM, Nichols CD, Goble DJ, Raz S.   +8 more
europepmc   +1 more source

Effect of liner properties on the analysis of lysergic acid diethylamide (LSD) analogs. [PDF]

J Forensic Sci
Shuda SA.
europepmc   +1 more source

Lysergic Acid Diethylamide (LSD) and the Heart: Exploring the Potential Impacts of LSD on Cardiovascular Function. [PDF]

Cureus
Suleria A, Verma S, Arya K, Stoltzfus MT, Gupta I, Singh B, Shaik T.   +6 more
europepmc   +1 more source