Results 11 to 20 of about 582,369 (357)

Lysine Catabolism Reprograms Tumour Immunity through Histone Crotonylation

open access: yesNature, 2023
Cancer cells rewire metabolism to favour the generation of specialized metabolites that support tumour growth and reshape the tumour microenvironment^ 1 , 2 .
Huairui Yuan   +17 more
semanticscholar   +1 more source

Class I histone deacetylases (HDAC1–3) are histone lysine delactylases

open access: yesbioRxiv, 2021
Lysine l-lactylation [K(l-la)] is a newly discovered histone mark that can be stimulated under conditions of high glycolysis, such as the Warburg effect. K(l-la) is associated with functions that are different from the widely studied histone acetylation.
C. Moreno-Yruela   +13 more
semanticscholar   +1 more source

A Proteome-Wide Atlas of Lysine-Reactive Chemistry

open access: yesNature Chemistry, 2021
Recent advances in chemical proteomics have begun to characterize the reactivity and ligandability of lysines on a global scale. Yet, only a limited diversity of aminophilic electrophiles have been evaluated for interactions with the lysine proteome ...
M. Abbasov   +13 more
semanticscholar   +1 more source

Industrial production of L-lysine in Corynebacterium glutamicum: Progress and prospects.

open access: yesMicrobiology Research, 2022
L-lysine is one of the amino acids necessary for humans and animals and widely used in food processing, pharmaceutical preparations and feed additives. In recent years, rational design based on systems metabolic engineering and conventional optimization ...
Jie Liu   +3 more
semanticscholar   +1 more source

Lysine succinylation, the metabolic bridge between cancer and immunity

open access: yesGenes and Diseases, 2022
Lysine succinylation is a naturally occurring post-translational modification (PTM) that regulates the stability and function of proteins. It can be regulated by enzymes such as SIRT5 and SIRT7.
Rui Shen   +6 more
semanticscholar   +1 more source

Comparing the Collision-Induced Dissociation of Trimethyl Lysine+ and Acetyl Lysine-H+

open access: yes, 2023
Experimental and computational results are reported on the reaction dynamics taking place within the collision-induced dissociation (CID) of Ne,Ne,Ne-Trimethyl-L-lysine+ (TMe-lysine+) and Ne-acetyl-L-lysine-H+ (acetyl-lysine-H+).
Kristopher, Kolonko   +4 more
core   +1 more source

Lysine-Sarcosine PiPo Functionalized Surface with Excellent Hemocompatibility

open access: yes, 2023
Polysarcosine (PSar) is an electrically neutral and excellently hydrophilic polypeptoid showing limited interaction with proteins and cells, which possesses better biocompatibility compared with polyethylene glycol. However, the immobilization of PSar is
Baoku Zhu   +9 more
core   +2 more sources

Lysine-Dependent Entropy Effects in the B. subtilis Lysine Riboswitch: Insights from Single-Molecule Thermodynamic Studies

open access: yes, 2021
Riboswitches play an important role in RNA-based sensing/gene regulation control for many bacteria. In particular, the accessibility of multiple conformational states at physiological temperatures allows riboswitches to selectively bind a cognate ligand ...
Andrea Marton Menendez (11879796)   +3 more
core   +1 more source

Extensive lysine methylation in hyperthermophilic crenarchaea : potential implications for protein stability and recombinant enzymes [PDF]

open access: yes, 2010
In eukarya and bacteria, lysine methylation is relatively rare and is catalysed by sequence-specific lysine methyltransferases that typically have only a single-protein target.
Botting, Catherine H.   +7 more
core   +1 more source

Dietary Lysine Levels Improved Antioxidant Capacity and Immunity via the TOR and p38 MAPK Signaling Pathways in Grass Carp, Ctenopharyngodon idellus Fry

open access: yesFrontiers in Immunology, 2021
An 8-week rearing trial was designed to appraise the dietary lysine levels on intestinal antioxidant capacity and immunity of grass carp fry. Six practical diets were prepared with graded levels of lysine (1.44, 1.79, 1.97, 2.44, 2.56 and 2.87% dry ...
Dongyu Huang   +8 more
doaj   +1 more source

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