Results 31 to 40 of about 873,878 (357)

Regulation of NF-κB activity through lysine monomethylation of p65 [PDF]

, 2009
NF-κB is a key activator of inflammatory and immune responses with important pathological roles in cancer, heart disease, and autoimmune diseases. Transcriptional activity of NF-κB is regulated by different posttranslational modifications.
Baltimore, David, Ea, Chee-Kwee
core   +3 more sources

Targeting AASS alleviates neurotoxicity and improves mitochondrial function in astrocyte models for pyridoxine-dependent epilepsy

Molecular Therapy: Nucleic Acids
Pyridoxine-dependent epilepsy (PDE) is a rare neurometabolic disorder of lysine catabolism caused by bi-allelic variants in ALDH7A1. This enzyme deficiency leads to accumulation of neurotoxic metabolites, pyridoxal-phosphate inactivation, and ...
Imke M.E. Schuurmans, Udo Engelke, Muna Abedrabbo, Sofía Puvogel, Rachel Mijdam, Gijs-Jan Scholten, Sara B. van Katwijk, Astrid Oudakker, Hilal H. Al-Shekaili, Dirk J. Lefeber, Blair R. Leavitt, Clara D.M. van Karnebeek, Nael Nadif Kasri, Alejandro Garanto   +13 more
doaj   +1 more source

Arginine and Lysine Promote Skeletal Muscle Hypertrophy by Regulating the mTOR Signaling Pathway in Bovine Myocytes

Meat and Muscle Biology, 2023
The objective of this study was to assess the effects of additional arginine (ARG) and lysine (LYS) on the regulatory factors associated with myogenic differentiation of bovine satellite cells and hypertrophy of myotubes.
Jongkyoo Kim, Won Seob Kim
doaj   +2 more sources

Gustatory sensitivity to amino acids in bumblebee mouthparts

Royal Society Open Science
Bees rely on amino acids from nectar and pollen for essential physiological functions. While nectar typically contains low (less than 1 mM) amino acid concentrations, levels in pollen are higher but variable (10–200 mM).
Sergio Rossoni, Rachel H. Parkinson, Jeremy E. Niven, Elizabeth Nicholls   +3 more
doaj   +1 more source

The effect of sodium valproate in Cushing's disease, Nelson's syndrome and Addison's disease [PDF]

, 1988
We investigated the effect of sodium valproate on plasma ACTH and serum cortisol concentrations in different pathological states of ACTH hypersecretion.
Allolio, B., Jaursch-Hancke, C., Kaulen, D., Reincke, Martin, Winkelmann, W.   +4 more
core   +1 more source

Effects of rumen-protected lysine on antler growth performance, fecal bacterial community, and blood gene expression in sika deer

Frontiers in Veterinary Science
IntroductionVelvet antler is an important product of sika deer (Cervus nippon), and its growth is closely related to dietary amino acid supplementation.
Bo Yang, Yuhang Zhu, Yongxiang Li, Yating Gao, Huazhe Si, Zhipeng Li, Zhipeng Li, Zhipeng Li, Zhipeng Li   +8 more
doaj   +1 more source

The Limiting Sequence and Appropriate Amino Acid Ratio of Lysine, Methionine, and Threonine for Seven- to Nine-Month-Old Holstein Heifers Fed Corn–Soybean M-Based Diet

Animals, 2019
An “Amino acid (AA) partial deletion method” was used in this experiment to study the limiting sequences and appropriate ratio of lysine (Lys), methionine (Met), and threonine (Thr) in the diets of 7- to 9-month-old Holstein heifers.
Yuan Li, Yanliang Bi, Qiyu Diao, Minyu Piao, Bing Wang, Fanlin Kong, Fengming Hu, Mengqi Tang, Yu Sun, Yan Tu   +9 more
doaj   +1 more source

Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum

Frontiers in Microbiology, 2021
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules.
Jingwen Huang, Jingwen Huang, Jiuzhou Chen, Yu Wang, Tuo Shi, Xiaomeng Ni, Wei Pu, Jiao Liu, Yingyu Zhou, Yingyu Zhou, Ningyun Cai, Shuangyan Han, Ping Zheng, Jibin Sun, Jibin Sun   +14 more
doaj   +1 more source

The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor. [PDF]

, 1988
The TCR is a complex receptor composed of seven polypeptide chains consisting of a ligand-binding subunit, Ti, and a putative signal-transducing subunit, CD3.
Chin, KN, Morley, BJ, Newton, ME, Weiss, A   +3 more
core   +1 more source

Co-Amorphous Andrographolide–Lysine with Unexpectedly Enhanced Solubility

Crystals
Andrographolide (ADG) is a typical poorly water-soluble drug, and a co-amorphous strategy was used here to improve its aqueous solubility. Co-amorphous systems of ADG and amino acids with a 1:1 molar ratio were screened via the neat ball milling method ...
Haifeng Luo, Yuchen Zheng, Shizhao Ren, Wangchuan Xiao, Rongrong Xue, Wei Han, Fenghua Chen   +6 more
doaj   +1 more source