Results 31 to 40 of about 609,507 (300)

A lysin to kill

eLife, 2016
An enzyme produced by a bacteriophage can enter human cells and kill intracellular Streptococcus pyogenes.
Anthony O Gaca, Michael S Gilmore
openaire   +5 more sources

Exigência de lisina para codornas japonesas (Coturnix japonica) na fase de cria Lysine requirement for growing japanese quails (Coturnix japonica)

Ciência e Agrotecnologia, 2007
Foram utilizadas 400 codornas fêmeas com peso médio de 7,3g + 0,3g no período de um a 42 dias de idade. O delineamento experimental foi o inteiramente casualizado, com cinco tratamentos e quatro repetições com 20 aves por unidade experimental.
Adolpho Marlon Antoniol de Moura, Rita da Trindade Ribeiro Nobre Soares, José Brandão Fonseca, Ricardo Augusto Mendonça Vieira, Humberto Pena Couto   +4 more
doaj   +1 more source

Arginine and Lysine Promote Skeletal Muscle Hypertrophy by Regulating the mTOR Signaling Pathway in Bovine Myocytes

Meat and Muscle Biology, 2023
The objective of this study was to assess the effects of additional arginine (ARG) and lysine (LYS) on the regulatory factors associated with myogenic differentiation of bovine satellite cells and hypertrophy of myotubes.
Jongkyoo Kim, Won Seob Kim
doaj   +2 more sources

Targeting AASS alleviates neurotoxicity and improves mitochondrial function in astrocyte models for pyridoxine-dependent epilepsy

Molecular Therapy: Nucleic Acids
Pyridoxine-dependent epilepsy (PDE) is a rare neurometabolic disorder of lysine catabolism caused by bi-allelic variants in ALDH7A1. This enzyme deficiency leads to accumulation of neurotoxic metabolites, pyridoxal-phosphate inactivation, and ...
Imke M.E. Schuurmans, Udo Engelke, Muna Abedrabbo, Sofía Puvogel, Rachel Mijdam, Gijs-Jan Scholten, Sara B. van Katwijk, Astrid Oudakker, Hilal H. Al-Shekaili, Dirk J. Lefeber, Blair R. Leavitt, Clara D.M. van Karnebeek, Nael Nadif Kasri, Alejandro Garanto   +13 more
doaj   +1 more source

Gustatory sensitivity to amino acids in bumblebee mouthparts

Royal Society Open Science
Bees rely on amino acids from nectar and pollen for essential physiological functions. While nectar typically contains low (less than 1 mM) amino acid concentrations, levels in pollen are higher but variable (10–200 mM).
Sergio Rossoni, Rachel H. Parkinson, Jeremy E. Niven, Elizabeth Nicholls   +3 more
doaj   +1 more source

Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum

Frontiers in Microbiology, 2021
Corynebacterium glutamicum is an important workhorse for industrial production of diversiform bioproducts. Precise regulation of gene expression is crucial for metabolic balance and enhancing production of target molecules.
Jingwen Huang, Jingwen Huang, Jiuzhou Chen, Yu Wang, Tuo Shi, Xiaomeng Ni, Wei Pu, Jiao Liu, Yingyu Zhou, Yingyu Zhou, Ningyun Cai, Shuangyan Han, Ping Zheng, Jibin Sun, Jibin Sun   +14 more
doaj   +1 more source

Acetylation site specificities of lysine deacetylase inhibitors in human cells [PDF]

, 2015
This work was supported by the Hallas Møller Investigator grant from the Novo Nordisk Foundation to C.C. S.A.W. and P.B. were supported by individual postdoctoral grants from the Danish Research Council (FSS: 10-085134, FSS: 12-12610). C.C.
Sebastian A Wagner, Jensen, Lars J., Jensen, Lars J, Chunaram Choudhary, Qi, Yun, Sonia Lain, Wagner, Sebastian A, Weinert, Brian T., James E Bradner, McCarthy, Anna R, Mann, Matthias, Yasuyuki Miyake, Westwood, Nicholas J, Schölz, Christian, Wagner, Sebastian A., Choudhary, Chunaram, Choudhary, Chuna Ram, Matthias, Patrick, Bradner, James E, Anna R McCarthy, Werner Streicher, Weinert, Brian Tate, Lain, Sonia, Bradner, James E., Matthias Mann, Nicholas J Westwood, Lars J Jensen, Jürgen Cox, Westwood, Nicholas James, Brian T Weinert, Cox, Jürgen, Christian Schölz, Streicher, Werner, McCarthy, Anna Rose, Lain, Sonya, Beli, Petra, Qi, Jun, Petra Beli, Jun Qi, Miyake, Yasuyuki, Patrick Matthias   +40 more
core   +1 more source

Effects of rumen-protected lysine on antler growth performance, fecal bacterial community, and blood gene expression in sika deer

Frontiers in Veterinary Science
IntroductionVelvet antler is an important product of sika deer (Cervus nippon), and its growth is closely related to dietary amino acid supplementation.
Bo Yang, Yuhang Zhu, Yongxiang Li, Yating Gao, Huazhe Si, Zhipeng Li, Zhipeng Li, Zhipeng Li, Zhipeng Li   +8 more
doaj   +1 more source

The Limiting Sequence and Appropriate Amino Acid Ratio of Lysine, Methionine, and Threonine for Seven- to Nine-Month-Old Holstein Heifers Fed Corn–Soybean M-Based Diet

Animals, 2019
An “Amino acid (AA) partial deletion method” was used in this experiment to study the limiting sequences and appropriate ratio of lysine (Lys), methionine (Met), and threonine (Thr) in the diets of 7- to 9-month-old Holstein heifers.
Yuan Li, Yanliang Bi, Qiyu Diao, Minyu Piao, Bing Wang, Fanlin Kong, Fengming Hu, Mengqi Tang, Yu Sun, Yan Tu   +9 more
doaj   +1 more source

New cationic nanovesicular systems containing lysine-based surfactants for topical administration: Toxicity assessment using representative skin cell lines [PDF]

, 2013
Many strategies for treating diseases require the delivery of drugs into the cell cytoplasm following internalization within endosomal vesicles. Thus, compounds triggered by low pH to disrupt membranes and release endosomal contents into the cytosol are ...
Vinardell, M. Pilar, Morán, María del Carmen, Vinardell Martínez-Hidalgo, Ma. Pilar, Mitjans, Montserrat, Mitjans Arnal, Montserrat, Morán Badenas, María del Carmen, Pérez, Lourdes, Martínez Ocaña, Verónica, Nogueira, Daniele R., Nogueira, Daniele Rubert, Pérez Muñoz, Lourdes, Martínez, Verónica Laura   +11 more
core   +1 more source