Results 221 to 230 of about 839,111 (286)

Exploring KAT6 as a therapeutic target in breast cancer: epigenetic approaches for precision medicine. [PDF]

NPJ Breast Cancer
Roussel-Simonin C, Fernandez-Martinez A, Postel-Vinay S, Mosele F, Viansone A, Massard C, Mouren A, Vibert J, Pistilli B.   +8 more
europepmc   +1 more source

Cholesterol‐DNA Origami Nanostructures for Synthetic Lipid Rafts Induce Early T Cell Activation Signals

Advanced Materials Interfaces, EarlyView.
Here, we present a nanotechnology approach to construct synthetic lipid rafts on the live T cell membrane, leveraging a versatile DNA origami‐enabled platform named as the “cholesterol nano‐patch” (CNP). Our investigation highlights the effectiveness of DNA nanotechnology in exploring the impact of nanoscale arrangement of cholesterols on the ...
Yunmin Jung, Young‐Joo Kim, Kunwoo Noh, Sunmi Lee, Minsuk Kwak   +4 more
wiley   +1 more source

Multi-omics profiling reveals downregulated tumor lysine metabolism reshaping the immune microenvironment and therapeutic responses in hepatocellular carcinoma. [PDF]

J Transl Med
Lu X, Qiang M, Li R, Guo C, Li K, Yao Y, Wang J, Wang C, Tu K, Chen Y, Xu Y.   +10 more
europepmc   +1 more source

Nonmulberry Silk Fibroin Doping Boosts Charge Transfer and Charge Injection in Aligned Polypyrrole‐Silk Scaffolds for Low‐Voltage Neurostimulation

Advanced Materials Interfaces, EarlyView.
Conductive silk‐polypyrrole scaffolds couple redox stability with cell‐affinitive peptides present innately in an endogenous silk fibroin, enabling optimized electrical stimulation to drive neurite outgrowth. Findings establish electrochemical‐biological link for biomaterial design rules for smart nerve guidance conduits that can provide low voltage ...
Rajiv Borah, Joseph Christakiran Moses, Jnanendra Upadhyay, Jitu Mani Das, Michael G. Monaghan, Biman B. Mandal   +5 more
wiley   +1 more source

Urinary acetylated protein as a biomarker of lupus nephritis: a prospective cohort study. [PDF]

Arthritis Res Ther
Lee YJ, Lee EJ, Kim K, Kim M, Yu JY, Kim M, Ahn SM, Hong S, Lee CK, Yoo B, Kim YG.   +10 more
europepmc   +1 more source

An Injection‐Molded Modified Silicone Rubber for Cancer‐on‐Chip Applications

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This study describes the characterization and application of an injection‐molded functionalized PDMS fluidic insert for the commercially available Micronit system. Modified PDMS can accommodate cell culture and is able to covalently bind proteins for long‐lasting coatings under flow‐conditions.
Ben J. Haspels, Frederikus Bakker, Lucas J. A. M. Beckers, Roland Kanaar, Koen C. Kriege, Susanne M. Valster, Roland C. M. Vulders, Maayke M. P. Kuijten   +7 more
wiley   +1 more source

Molecular mechanism of biocompatible clusteroluminogens from citric acid and l-lysine. [PDF]

RSC Adv
Zhang Q, Sun P, Li B.
europepmc   +1 more source

Microwave‐Assisted Aqueous Synthesis of Gelatin‐Norbornene for Hydrogel Crosslinking and Bioprinting

Advanced Materials Technologies, EarlyView.
A microwave‐assisted reaction is utilized to synthesize gelatin‐norbornene (GelNB), achieving a high degree of norbornene functionalization while reducing the macromer's upper critical solution temperature. The resulting GelNB macromer has high solubility at room temperature, facilitating light‐based 3‐dimensional (3D) printing of thiol‐norbornene ...
Jonathan B. Bryan, Chien‐Chi Lin
wiley   +1 more source

Acetylation dynamics of MrATG4 governing autophagy-mediated conidiation in an entomopathogenic fungus. [PDF]

PLoS Pathog
Yu D, Wang Y, Xie R, Zhou R, Liu Z, Shi N, Xie X, Yang Y, Qu J, Yang G, Huang B.   +10 more
europepmc   +1 more source

Two‐Photon Polymerized Microvascular Environments for Multicellular Modeling of the Blood–Brain Tumor Barrier

Advanced Materials Technologies, EarlyView.
Modeling the blood–brain tumor barrier is challenging due to complex interactions between brain microvasculature and glioma cells. We present two‐photon polymerized 3D micro‐porous capillary‐like structures that support endothelial alignment, cytoskeletal organization, and pericyte‐endothelial‐glioma tri‐cultures.
Nastaran Barin, Sayba Z. Chowdhury, Maurice de Wit, Rania Head, Kiki Bals, Erwin Brosens, Marvin M. van Luijn, Hayri E. Balcioglu, Angelo Accardo, Pim J. French   +9 more
wiley   +1 more source