Results 81 to 90 of about 851,277 (331)

Lysine metabolism in mammals [PDF]

open access: yesBiochemical Journal, 1973
The enzymes involved in the initial degradative steps of lysine metabolism, lysine–2-oxoglutarate reductase and saccharopine dehydrogenase, were studied and their activities in different mammals compared. Values obtained in human, rat, pig, dog, cat, ox and sheep liver indicated that in vitro, appreciable degradation of lysine to saccharopine (4–6nmol ...
Florence C. I. Fellows   +1 more
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

open access: yesFEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian   +6 more
wiley   +1 more source

ATXR5 and ATXR6 are H3K27 monomethyltransferases required for chromatin structure and gene silencing. [PDF]

open access: yes, 2009
Constitutive heterochromatin in Arabidopsis thaliana is marked by repressive chromatin modifications, including DNA methylation, histone H3 dimethylation at Lys9 (H3K9me2) and monomethylation at Lys27 (H3K27me1).
Bernatavichute, Yana V   +9 more
core   +1 more source

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

open access: yesFEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić   +3 more
wiley   +1 more source

A procedure to evaluate the efficiency of utilization of dietary amino acid for poultry

open access: yesActa Scientiarum: Animal Sciences, 2014
The aim of this study was to develop a procedure based on Gompertz function to determine the efficiency of utilization of amino acid. The procedure was applied to determine the efficiency of utilization of dietary lysine, methionine+cystine and threonine
Edney Pereira da Silva   +5 more
doaj   +1 more source

The effect of phase-feeding on the growth performance, carcass characteristics and nitrogen balance of growing and finishing pigs. [PDF]

open access: yes, 2007
peer-reviewedA completely randomised design experiment was conducted to determine if grouphoused grower-finisher pigs (43.9 to 95 kg) show differences in performance and nitrogen utilisation when provided with a single high lysine diet (11 g/kg) or with ...
Garry, B.P.   +2 more
core  

Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand [PDF]

open access: yes, 1992
We have constructed an artificial ligand for the hepatocyte-specific asialoglycoprotein receptor for the purpose of generating a synthetic delivery system for DNA.
Ashwell G.   +36 more
core   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

open access: yesFEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi   +5 more
wiley   +1 more source

Does the size of larval groups influence the effect of metabolic inhibitors on the development of Phormia regina (Diptera: Calliphoridae) larvae?

open access: yesEuropean Journal of Entomology, 2002
A series of experiments were conducted to compare the susceptibility of P. regina larvae reared in isolation or in groups to the effects of diet-borne metabolic inhibitors: chlorogenic acid (CGA) and mimosine.
Paul W.C. GREEN   +2 more
doaj   +1 more source

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