Results 161 to 170 of about 76,328 (190)

Influence of N^ε-Lysine Acetylation on the Formation of Protein Aggregates and Antibiotic Persistence in E. coli. [PDF]

Molecules
Stojowska-Swędrzyńska K, Kuczyńska-Wiśnik D, Laskowska E.   +2 more
europepmc   +1 more source

Acetylome Analyses Provide New Insights Into the Effects of Childhood Allergic Rhinitis on Olfactory Bulb‐Dependent Olfactory Impairment

Allergy, EarlyView.
Ruikun Wang, Ziying Xu, Yimin Zhang, Qian Wang, Mengyao Li, Jieqiong Liang, Xiaojun Zhan, YinXia Lu, Jing Yuan, Shan Wang, Qinglong Gu   +10 more
wiley   +1 more source

Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases

The FEBS Journal, EarlyView.
Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek, Miroslava Vosahlikova, Zsofia Kutil, Zora Novakova, Julia Kudlacova, Ruzena Tuckova, Marat Meleshin, Barbora Havlinova, Pavlina Jaklova, Jana Ptackova, Cordelia Schiene‐Fischer, Mike Schutkowski, Cyril Barinka   +12 more
wiley   +1 more source

Clostridium autoethanogenum alters cofactor synthesis, redox metabolism, and lysine-acetylation in response to elevated H₂:CO feedstock ratios for enhancing carbon capture efficiency. [PDF]

Biotechnol Biofuels Bioprod
Davin ME, Thompson RA, Giannone RJ, Mendelson LW, Carper DL, Martin MZ, Martin ME, Engle NL, Tschaplinski TJ, Brown SD, Hettich RL.   +10 more
europepmc   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

Caffeine improves mitochondrial dysfunction in the white matter of neonatal rats with hypoxia-ischemia through deacetylation: a proteomic analysis of lysine acetylation. [PDF]

Front Mol Neurosci
Zhang Y, Wang Y, Dou H, Wang S, Qu D, Peng X, Zou N, Yang L.   +7 more
europepmc   +1 more source

Current perspectives on KMT2A fusion proteins and menin inhibition in paediatric acute myeloid leukaemia

The FEBS Journal, EarlyView.
Genetic rearrangements resulting in the expression of KMT2A fusion alleles can lead to dramatic transcriptional disturbances that contribute to the onset of acute leukaemias. Fortunately, menin inhibition has emerged as a promising new class of targeted therapy.
Lydia Elaine Roets, Graeme Greenfield, Katrina Mairead Lappin   +2 more
wiley   +1 more source

N^ε-lysine acetylation of the histone-like protein HBsu influences antibiotic survival and persistence in <i>Bacillus subtilis</i>. [PDF]

Front Microbiol
Carr RA, Tucker T, Newman PM, Jadalla L, Jaludi K, Reid BE, Alpheaus DN, Korrapati A, Pivonka AE, Carabetta VJ.   +9 more
europepmc   +1 more source

Proteomic analysis of the zone of degeneration at the mitosis–meiosis transition stage in wild‐caught male catshark (Scyliorhinus canicula), correlated with an unusually high‐water temperature in the English Channel

Journal of Fish Biology, EarlyView.
Abstract In the context of current global change, variations in water temperature are one of the environmental conditions with serious consequences for marine life, including reproductive processes. In the small spotted catshark Scyliorhinus canicula, spermatogenesis occurs in spermatocysts composed of synchronously developing germ cells associated ...
Fabian Jeanne, Stanislas Pilet, Sean Heighton, Benoît Bernay, Pascal Sourdaine   +4 more
wiley   +1 more source

Protein lysine acetylation does not contribute to the high rates of fatty acid oxidation seen in the post-ischemic heart. [PDF]

Sci Rep
Ketema EB, Ahsan M, Zhang L, Karwi QG, Lopaschuk GD.   +4 more
europepmc   +1 more source