Results 51 to 60 of about 4,831 (203)

Succinylated Octopamine Ascarosides and a New Pathway of Biogenic Amine Metabolism in Caenorhabditis elegans [PDF]

, 2013
The ascarosides, small-molecule signals derived from combinatorial assembly of primary metabolism-derived building blocks, play a central role in Caenorhabditis elegans biology and regulate many aspects of development and behavior in this model ...
Artyukhin, Alexander B., Avery, Leon, Baugh, L. Ryan, Bose, Neelanjan, Cheong, Micheong, Izrayelit, Yevgeniy, Jo, Yeara, Jordan, James M., Schroeder, Frank C., Srinivasan, Jagan, Sternberg, Paul W., von Reuss, Stephan H., Yim, Joshua J.   +12 more
core   +2 more sources

SuccSite: Incorporating Amino Acid Composition and Informative k-spaced Amino Acid Pairs to Identify Protein Succinylation Sites

Genomics, Proteomics & Bioinformatics, 2020
Protein succinylation is a biochemical reaction in which a succinyl group (-CO-CH2-CH2-CO-) is attached to the lysine residue of a protein molecule. Lysine succinylation plays important regulatory roles in living cells. However, studies in this field are
Hui-Ju Kao, Van-Nui Nguyen, Kai-Yao Huang, Wen-Chi Chang, Tzong-Yi Lee   +4 more
doaj   +1 more source

Protocol for the preparation of site-specific succinylated histone mimics to investigate the impact on nucleosome dynamics

STAR Protocols, 2021
Summary: Lysine succinylation is a recently discovered posttranslational modification that plays critical roles in metabolism, epigenetic signaling, and human diseases.
Yihang Jing, Zheng Liu, Xiang David Li
doaj   +1 more source

The Plant PTM Viewer, a central resource for exploring plant protein modifications [PDF]

, 2019
Posttranslational modifications (PTMs) of proteins are central in any kind of cellular signaling. Modern mass spectrometry technologies enable comprehensive identification and quantification of various PTMs.
Botzki, Alexander, De Smet, Ive, Gevaert, Kris, Goormachtig, Sofie, Horne, Alison, Van Breusegem, Frank, Van Parys, Thomas, Willems, Patrick   +7 more
core   +1 more source

Identification of lysine succinylation as a new post-translational modification [PDF]

Nature Chemical Biology, 2010
Of the 20 ribosomally coded amino acid residues, lysine is the most frequently post-translationally modified, which has important functional and regulatory consequences. Here we report the identification and verification of a previously unreported form of protein post-translational modification (PTM): lysine succinylation.
Zhihong, Zhang, Minjia, Tan, Zhongyu, Xie, Lunzhi, Dai, Yue, Chen, Yingming, Zhao   +5 more
openaire   +2 more sources

Acetylome and Succinylome Profiling of Edwardsiella tarda Reveals Key Roles of Both Lysine Acylations in Bacterial Antibiotic Resistance

Antibiotics, 2022
The antibiotic resistance of Edwardsiella tarda is becoming increasingly prevalent, and thus novel antimicrobial strategies are being sought. Lysine acylation has been demonstrated to play an important role in bacterial physiological functions, while its
Yuying Fu, Lishan Zhang, Huanhuan Song, Junyan Liao, Li Lin, Wenjia Jiang, Xiaoyun Wu, Guibin Wang   +7 more
doaj   +1 more source

Effects of increasing acylation and enzymatic hydrolysis on functional properties of bambara bean (Vigna subterranea) protein concentrate [PDF]

, 2013
Bambara bean protein concentrate was acylated and partially hydrolysed with pancreatin in order to improve its functional properties. Increasing acetylation and succinylation (from 0.0 to 1.0 g anhydride/g concentrate) modified lysine at similar rate ...
Mbome, I., Minka, S., Mune Mune, M.
core   +1 more source

Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway

BMC Genomics, 2017
Background Lysine succinylation is a ubiquitous and important protein post-translational modification in various eukaryotic and prokaryotic cells. However, its functions in Dendrobium officinale, an important traditional Chinese orchid herb with high ...
Shangguo Feng, Kaili Jiao, Hong Guo, Mengyi Jiang, Juan Hao, Huizhong Wang, Chenjia Shen   +6 more
doaj   +1 more source

Peptide inhibitors of Streptomyces DD-carboxypeptidases [PDF]

, 1973
1. Peptides that inhibit the dd-carboxypeptidases from Streptomyces strains albus G and R61 were synthesized. They are close analogues of the substrates of these enzymes.
Frère, Jean-Marie, Ghuysen, Jean-Marie, Leyh-Bouille, Mélina, Nieto, Manuel, Perkins, Harnold R.   +4 more
core   +1 more source

Global Insights Into Lysine Acylomes Reveal Crosstalk Between Lysine Acetylation and Succinylation in Streptomyces coelicolor Metabolic Pathways [PDF]

Molecular & Cellular Proteomics, 2021
Lysine acylations are reversible and ubiquitous post-translational modifications that play critical roles in regulating multiple cellular processes. In the current study, highly abundant and dynamic acetylation, besides succinylation, was uncovered in a soil bacterium, Streptomyces coelicolor.
Yujiao Yang, Hong Zhang, Zhenyang Guo, Siwei Zou, Fei Long, Jiacheng Wu, Peng Li, Guo-ping Zhao, Wei Zhao   +8 more
openaire   +2 more sources