Results 71 to 80 of about 39,604 (271)

Bacteriophage 434 Hex Protein Prevents RecA-Mediated Repressor Autocleavage

Viruses, 2013
In a λimm434 lysogen, two proteins are expressed from the integrated prophage. Both are encoded by the same mRNA whose transcription initiates at the PRM promoter. One protein is the 434 repressor, needed for the establishment and maintenance of
Paul Shkilnyj, Michael P. Colon, Gerald B. Koudelka   +2 more
doaj   +1 more source

Exponential sensitivity of noise-driven switching in genetic networks [PDF]

, 2008
Cells are known to utilize biochemical noise to probabilistically switch between distinct gene expression states. We demonstrate that such noise-driven switching is dominated by tails of probability distributions and is therefore exponentially sensitive ...
Mehta, Pankaj, Mukhopadhyay, Ranjan, Wingreen, Ned S.   +2 more
core   +3 more sources

Nanoneedle‐Based Electroporation for Efficient Manufacturing of Human Primary Chimeric Antigen Receptor Regulatory T‐Cells

Advanced Science, EarlyView.
Low reproducibility and inefficient gene transfer hamper clinical manufacturing of chimeric antigen receptor regulatory T cells (CAR Tregs). Nanoneedle mediated electroporation generates primary human CAR Tregs under good manufacturing practice conditions with superior efficiency compared to viral transduction.
Ningjia Sun, Cong Wang, William Edwards, Yikai Wang, Xiangrong L. Lu, Chenlei Gu, Samuel McLennan, Panicos Shangaris, Peng Qi, Daniela Mastronicola, Cristiano Scottà, Giovanna Lombardi, Ciro Chiappini   +12 more
wiley   +1 more source

Human Group A Streptococci Virulence Genes in Bovine Group C Streptococci

Emerging Infectious Diseases, 2010
Phage-encoded virulence genes of group A streptococci were detected in 10 (55.6%) of 18 isolates of group C streptococci that had caused bovine mastitis.
Márcia G. Rato, Ricardo Bexiga, Sandro F. Nunes, Cristina L. Vilela, Ilda Santos-Sanches   +4 more
doaj   +1 more source

SVep1, a temperate phage of human oral commensal Streptococcus vestibularis

Frontiers in Microbiology, 2023
IntroductionBacteriophages play a vital role in the human oral microbiome, yet their precise impact on bacterial physiology and microbial communities remains relatively understudied due to the limited isolation and characterization of oral phages.
Miaomiao Wu, Yanpeng Zhu, Yuhui Yang, Yali Gong, Zongyue Chen, Binyou Liao, Yu Xiong, Xia Zhou, Xia Zhou, Yan Li   +9 more
doaj   +1 more source

Impact of Virus‐Mediated Modifications in Bacterial Communities on the Accumulation of Soil Organic Carbon

Advanced Science, EarlyView.
This study illustrates the impact of viruses on carbon cycling in soils with different availabilities of carbon. In conditions of low carbon availability, viruses adopt a lysogenic lifestyle, integrate into the host genomes and facilitate the degradation of carbon.
Mingfeng Liu, Guixiang Zhou, Congzhi Zhang, Lin Chen, Donghao Ma, Lijun Zhang, Chunhua Jia, Ling Ma, Jiabao Zhang   +8 more
wiley   +1 more source

Role of Lysogenic Phages in the Dissemination of Antibiotic Resistance Genes Applied in the Food Chain

Foods
Bacteriophages, first discovered in 1915, have re-emerged as critical players in microbial ecosystems, particularly in food production. Their ability to lysogenize bacterial hosts raises concerns about their role in the horizontal transfer of antibiotic ...
Rafael Dorighello Cadamuro, Mariana Alves Elois, Giulia Von Tönnemann Pilati, Beatriz Pereira Savi, Leonardo Pessi, Yasmin Ferreira Souza Hoffmann Jempierre, David Rodríguez-Lázaro, Gislaine Fongaro   +7 more
doaj   +1 more source

Characterization and Reuse of Lithium‐ion Battery Cathode Material Recovered Through a Bacterial Process

Advanced Energy Materials, EarlyView.
A sustainable bacteria‐based lithium‐ion battery cathode recycling method is optimized using engineering biology. The resulting biomineralized manganese carbonate species is found to be easily converted into an electrode material, via simple calcination.
Virginia Echavarri‐Bravo, Isolde Marsland, Mai‐Britt V. Jensen, Caroline Kirk, Louise E. Horsfall   +4 more
wiley   +1 more source

A computational systems biology study of the lambda-lac mutants [PDF]

arXiv, 2007
We present a comprehensive computational study of some 900 possible "lambda-lac" mutants of the lysogeny maintenance switch in phage lambda, of which up to date 19 have been studied experimentally (Atsumi & Little, PNAS 103: 4558-4563, (2006)). We clarify that these mutants realise regulatory schemes quite different from wild-type lambda, and can ...
arxiv  

Functional Silver‐Loaded Porous Composite Scaffold for Bone Tissue Bacterial Infection

Advanced NanoBiomed Research, EarlyView.
In the current study, a AgNP‐loaded gelatin/β‐tricalcium phosphate composite scaffold was developed. Its interconnected porous structure facilitated cell adhesion and proliferation while enhancing osteogenic differentiation‐related gene expression to support bone regeneration.
An'nan Hu, Jian Zhou
wiley   +1 more source