Results 11 to 20 of about 32,338 (252)
Synthesis of Lysophosphatidylcholine and Mixed Phosphatidylcholine [PDF]
The Journal of Organic Chemistry, 2022 Lysophosphatidylcholine (LPC) and phosphatidylcholine (PC) are important membrane constituents implicated in signaling and immune regulation. Synthesis of LPCs is challenging due to rapid acyl migration, e.g., induced by chromatography. We here report a highly regioselective synthesis of LPC and mixed PC via an intermediate allowing specific terminal ...
Athanasios Papangelis, Trond Ulven
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Journal of Lipid Research, 1993 The role of the lysosome in the metabolism of lysophosphatidylcholine was investigated in isolated rat hepatocytes. Chloroquine, primaquine, and ammonium chloride caused a 2.5-fold increase in radioactive lysophosphatidylcholine in [methyl-3H]choline ...
GM Hatch, A Oskin, DE Vance
doaj +3 more sources
A sensitive method for the quantitation of lysophosphatidylcholine in canine heart.
Journal of Lipid Research, 1985 We have developed a procedure for the determination of small amounts of lysophosphatidylcholine in cardiac tissue. Lysophosphatidylcholine from canine heart was separated from the major phospholipids by column chromatography, and then acetylated with ...
M Wientzek, G Arthur, R Y Man, P C Choy
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The Action Mode of Lysophosphatidylcholine in Human Monocytes
Journal of Pharmacological Sciences, 2004 To elucidate the action and signal transduction of lysophosphatidylcholine (LPC), we challenged a set of LPC on U937 human monocytes and found that LPC mobilized Ca(2+). The Ca(2+) response was not blocked by pertussis toxin, an inhibitor of G(i/o) proteins, or by U73122, a phospholipase C inhibitor.
Yun, Mi-Ran +2 more
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iPLA2β Contributes to ER Stress-Induced Apoptosis during Myocardial Ischemia/Reperfusion Injury
Cells, 2021 Both calcium-independent phospholipase A2 beta (iPLA2β) and endoplasmic reticulum (ER) stress regulate important pathophysiological processes including inflammation, calcium homeostasis and apoptosis.
Tingting Jin +11 more
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Di-san junyi daxue xuebao, 2021 Objective To explore the alteration profile of lysophosphatidylcholine (LPC) content in donor liver with the elapse of total ischemic time and investigate its application value in the evaluation of donor liver quality. Methods A total of 100 patients who
WANG Hong +5 more
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Biomolecules, 2023 Lysosomes are degradative organelles that facilitate the removal and recycling of potentially cytotoxic materials and mediate a variety of other cellular processes, such as nutrient sensing, intracellular signaling, and lipid metabolism.
Jacob M. Albright +4 more
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Cells, 2023 Synovial fluid (SF) from human knee joints with osteoarthritis (OA) has elevated levels of lysophosphatidylcholine (LPC) species, but their functional role is not well understood.
Thomas Timm +5 more
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Frontiers in Cell and Developmental Biology, 2022 Sepsis is predominantly initiated by bacterial infection and can cause systemic inflammation, which frequently leads to rapid death of the patient. However, this acute systemic inflammatory response requires further investigation from the perspectives of
Soi Jeong +12 more
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Signaling mechanisms and neutrophil modulation through the lysophosphatidylcholine receptor, G2A.
, 2006 Signaling mechanisms and neutrophil modulation through the lysophosphatidylcholine receptor ...
Phoebe. Lin (7987631)
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