Results 21 to 30 of about 39,809 (251)

A sensitive method for the quantitation of lysophosphatidylcholine in canine heart.

Journal of Lipid Research, 1985
We have developed a procedure for the determination of small amounts of lysophosphatidylcholine in cardiac tissue. Lysophosphatidylcholine from canine heart was separated from the major phospholipids by column chromatography, and then acetylated with ...
M Wientzek, G Arthur, R Y Man, P C Choy
doaj   +1 more source

Studies on the compounds lipids from X-ray irradiated animal,1. [PDF]

, 1962
For the purpose to reveal the mechanism of the biological indirect action of X-rays the author has conducted the analysis of the compound lipids of the organs of the rabbits irradiated with X-rays.
Ohara, Sachiko
core   +1 more source

Lysophosphatidylcholine Induces NLRP3 Inflammasome-Mediated Foam Cell Formation and Pyroptosis in Human Monocytes and Endothelial Cells

Frontiers in Immunology, 2020
Foam cells are specialized lipid-loaded macrophages derived from monocytes and are a key pathological feature of atherosclerotic lesions. Lysophosphatidylcholine (LPC) is a major lipid component of the plasma membrane with a broad spectrum of ...
Rafael Corrêa, Luís Felipe Fonseca Silva, Dalila Juliana Silva Ribeiro, Raquel das Neves Almeida, Igor de Oliveira Santos, Luís Henrique Corrêa, Lívia Pimentel de Sant'Ana, Leonardo Santos Assunção, Patrícia T. Bozza, Kelly Grace Magalhães   +9 more
doaj   +1 more source

Canonical and Novel Non-Canonical Cholinergic Agonists Inhibit ATP-Induced Release of Monocytic Interleukin-1β via Different Combinations of Nicotinic Acetylcholine Receptor Subunits α7, α9 and α10

Frontiers in Cellular Neuroscience, 2017
Recently, we discovered a cholinergic mechanism that inhibits the adenosine triphosphate (ATP)-dependent release of interleukin-1β (IL-1β) by human monocytes via nicotinic acetylcholine receptors (nAChRs) composed of α7, α9 and/or α10 subunits ...
Anna Zakrzewicz, Katrin Richter, Alisa Agné, Sigrid Wilker, Kathrin Siebers, Bijan Fink, Gabriela Krasteva-Christ, Gabriela Krasteva-Christ, Gabriela Krasteva-Christ, Mike Althaus, Mike Althaus, Winfried Padberg, Arik J. Hone, J. Michael McIntosh, J. Michael McIntosh, J. Michael McIntosh, Veronika Grau, Veronika Grau   +17 more
doaj   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna, Kim, Kyoungmi, Litwin, Tomasz, Mazi, Tagreed A, Medici, Valentina, Sarode, Gaurav V, Shibata, Noreene M   +6 more
core   +2 more sources

Generation and characterization of a mitotane-resistant adrenocortical cell line [PDF]

, 2020
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy.
Bachmann, Sebastian, Bahethi, Rohini, Beule, Dieter, Choi, Murim, Eisenhofer, Graeme, Liebisch, Gerhard, Messerschmidt, Clemens, Obermayer, Benedikt, Peitzsch, Mirko, Scholl, Ute I., Schrade, Petra, Seidel, Eric, Walenda, Gudrun, Wallace, Paal, Yoo, Taekyeong   +14 more
core   +2 more sources

Lysophosphatidylcholine Promotes Phagosome Maturation and Regulates Inflammatory Mediator Production Through the Protein Kinase A–Phosphatidylinositol 3 Kinase–p38 Mitogen-Activated Protein Kinase Signaling Pathway During Mycobacterium tuberculosis Infection in Mouse Macrophages

Frontiers in Immunology, 2018
Tuberculosis is caused by the infectious agent Mycobacterium tuberculosis (Mtb). Mtb has various survival strategies, including blockade of phagosome maturation and inhibition of antigen presentation. Lysophosphatidylcholine (LPC) is a major phospholipid
Hyo-Ji Lee, Hyo-Ji Lee, Hyun-Jeong Ko, Dong-Kun Song, Yu-Jin Jung   +4 more
doaj   +1 more source

Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits

Journal of Lipid Research, 2002
Lysophosphatidic acid (LPA) is a biologically active phospholipid that has been identified as a vasoactive principle in incubated plasma and serum of mammals.
Akira Tokumura, Yumi Kanaya, Masaki Kitahara, Maki Miyake, Yasuko Yoshioka, Kenji Fukuzawa   +5 more
doaj   +1 more source

Lysophosphatidylcholine-cholesterol complex.

Journal of Biological Chemistry, 1982
Lysophosphatidylcholine (lysoPC) and cholesterol at 1:1 molar ratio form multilamellar and, on sonication, unilamellar liposomes in water. Calorimetric scannings of varied mixtures in water give evidence for the existence of a 1:1 complex of the lipids.
L S, Ramsammy, H, Brockerhoff
openaire   +2 more sources

Leucoreduction of blood components. an effective way to increase blood safety? [PDF]

, 2015
Over the past 30 years, it has been demonstrated that removal of white blood cells from blood components is effective in preventing some adverse reactions such as febrile non-haemolytic transfusion reactions, immunisation against human leucocyte antigens
Bianchi, Maria, Facco, Giuseppina, Grazzini, Giuliano, Liumbruno, Giancarlo M, Marano, Giuseppe, Pupella, Simonetta, VAGLIO, Stefania   +6 more
core   +1 more source