Results 21 to 30 of about 27,042 (202)
Methods for the preparation of lysophosphatidylcholine
Journal of Pharmacy and Pharmacology, 1971 Abstract The surfactant and solubilizing properties of lysophosphatidylcholine (LPC) could have industrial uses if it became available in technical quantity and purity. The two most promising routes for obtaining it are isolation from cereal starches and mono-deacylation of egg phosphatidylcholine (PC). Baker's yeast autolysed by Letters'
D S, Merryfield, J J, Wren
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Frontiers in Pharmacology, 2020 Ulcerative colitis (UC) causes chronic inflammation and damage to the colonic mucosal layer. Recent studies have reported significant changes in phosphatidylcholine (PC) and lysophosphatidylcholine (LPC) in UC patients and oral administration of PC has ...
Lixiang Zhai +12 more
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ATP Release Drives Inflammation with Lysophosphatidylcholine [PDF]
ImmunoHorizons, 2020 Abstract Lysophosphatidylcholine (LPC), a dominant lipid component of oxidized low-density lipoprotein, plays a major role in inflammation associated with atherosclerosis and neurodegenerative disorders. It activates inflammatory responses from macrophages, neuronal cells, and endothelial cells.
Sana, Ismaeel, Ayub, Qadri
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A sensitive method for the quantitation of lysophosphatidylcholine in canine heart.
Journal of Lipid Research, 1985 We have developed a procedure for the determination of small amounts of lysophosphatidylcholine in cardiac tissue. Lysophosphatidylcholine from canine heart was separated from the major phospholipids by column chromatography, and then acetylated with ...
M Wientzek, G Arthur, R Y Man, P C Choy
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The presence of lysophosphatidylcholine in chromaffin granules [PDF]
Biochemical Journal, 1980 Lysophosphatidylcholine is thought to be a characteristic component of the chromaffin granules in adrenal glands. By the use of a t.l.c. system that resolves minor phospholipids satisfactorily, this subcellular location was confirmed in the present study in bovine glands.
G, Arthur, A, Sheltawy
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A specific serum lipid signature characterizes patients with glycogen storage disease type Ia
Journal of Lipid ResearchGlycogen storage disease type Ia (GSDIa) is a rare, inherited glucose-6-phosphatase-α (G6Pase-α) deficiency-induced carbohydrate metabolism disorder.
Alessandro Rossi +11 more
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Diabetes, Metabolic Syndrome and Obesity, 2022 Li Bao,1,2 Ying Zhang,2,3 Sichao Yan,1,2 Dan Yan,2,3 Dechun Jiang1,2 1Department of Pharmacy, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Key Laboratory of Bio-Characteristic Profiling for ...
Bao L, Zhang Y, Yan S, Yan D, Jiang D
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Journal of Lipid Research, 1998 To determine the respective roles of endothelial cells from brain capillaries and astrocytes in the conversion of circulating 18:2n–6 and 18:3n–3 into 20:4n–6 and 22:6n–3, respectively, a coculture of the two cell types mimicking the in vivo blood–brain ...
N. Bernoud +8 more
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Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes [PDF]
Journal of Lipid Research, 2008 The pathogenesis of nonalcoholic steatohepatitis (NASH) is unclear, despite epidemiological data implicating FFAs. We studied the pathogenesis of NASH using lipoapoptosis models. Palmitic acid (PA) induced classical apoptosis of hepatocytes. PA-induced lipoapoptosis was inhibited by acyl-CoA synthetase inhibitor but not by ceramide synthesis inhibitors,
Myoung Sook Han +15 more
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Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice
Biomedicines, 2022 Glucotoxic metabolites and pathways play a crucial role in diabetic complications, and new treatment options which improve glucotoxicity are highly warranted. In this study, we analyzed bezafibrate (BEZ) treated, streptozotocin (STZ) injected mice, which
Andras Franko +12 more
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