Results 41 to 50 of about 39,610 (238)

A specific serum lipid signature characterizes patients with glycogen storage disease type Ia

Journal of Lipid Research
Glycogen storage disease type Ia (GSDIa) is a rare, inherited glucose-6-phosphatase-α (G6Pase-α) deficiency-induced carbohydrate metabolism disorder.
Alessandro Rossi, Margherita Ruoppolo, Roberta Fedele, Francesca Pirozzi, Carmen Rosano, Renata Auricchio, Daniela Melis, Pietro Strisciuglio, Maaike H. Oosterveer, Terry G.J. Derks, Giancarlo Parenti, Marianna Caterino   +11 more
doaj   +1 more source

Lysophosphatidylcholine (17:0) Improves HFD-Induced Hyperglycemia & Insulin Resistance: A Mechanistic Mice Model Study

Diabetes, Metabolic Syndrome and Obesity, 2022
Li Bao,1,2 Ying Zhang,2,3 Sichao Yan,1,2 Dan Yan,2,3 Dechun Jiang1,2 1Department of Pharmacy, Beijing Shijitan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2Beijing Key Laboratory of Bio-Characteristic Profiling for ...
Bao L, Zhang Y, Yan S, Yan D, Jiang D
doaj  

Bezafibrate Reduces Elevated Hepatic Fumarate in Insulin-Deficient Mice

Biomedicines, 2022
Glucotoxic metabolites and pathways play a crucial role in diabetic complications, and new treatment options which improve glucotoxicity are highly warranted. In this study, we analyzed bezafibrate (BEZ) treated, streptozotocin (STZ) injected mice, which
Andras Franko, Martin Irmler, Cornelia Prehn, Silke S. Heinzmann, Philippe Schmitt-Kopplin, Jerzy Adamski, Johannes Beckers, Jürgen-Christoph von Kleist-Retzow, Rudolf Wiesner, Hans-Ulrich Häring, Martin Heni, Andreas L. Birkenfeld, Martin Hrabě de Angelis   +12 more
doaj   +1 more source

Metabolites involved in cellular communication among human cumulus-oocyte-complex and sperm during in vitro fertilization [PDF]

, 2015
Background: Fertilization is a key physiological process for the preservation of the species. Consequently, different mechanisms affecting the sperm and the oocyte have been developed to ensure a successful fertilization. Thus, sperm acrosome reaction is
Avilés Sánchez, Manuel, Bernabeu, Rafael, García Hernández, Eva María, Gil-Izquierdo, Ángel, González-Brusi, Leopoldo, Guerrero, Jaime, Gómez-Torres, María José, Izquierdo-Rico, María José, Medina, Sonia, Orduna, Jesús, Savirón, María, Ten Morro, Jorge   +11 more
core   +2 more sources

Noncanonical atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - A trace collection

Journal of Lipid Research, 2023
Pathogenic mechanisms in degenerative thoracic aortic aneurysms (TAA) are still unclear. There is an ongoing debate about whether TAAs are caused by uniform or distinct processes, which would obviously have a major impact on future treatment strategies ...
Christian Doppler, Barbara Messner, Teresa Mimler, Bruno Schachner, Marlene Rezk, Clara Ganhör, Christian Wechselberger, Marina Müller, Spela Puh, Johannes Pröll, Barbara Arbeithuber, Thomas Müller, Andreas Zierer, David Bernhard   +13 more
doaj   +1 more source

The effect of experimental hyperoxia on erythrocytes’ oxygen-transport function [PDF]

, 2018
The aim of this study was to investigate the effect of hyperoxia, calcium ions and pH value on the composition of major phospholipids in human erythrocyte membranes and erythrocytes’ oxygen-transport function. To create a model of hyperoxia, we saturated
Alexander Alexandrovich Moskovkin, Alexander Yurievich Tychkov, Anastasia Nikolaevna Kukina, Anastasia Yurievna Samonova, Bligh EA, Borza C, Dobrotyna NA, Drgová A, Elvira Sergeevna Revina, Gavrilov VB, Gavrilov VB, Igor Pavlovich Grunyushkin, Jean-Christophe Bourdon, Litvitskiy PF, Marangoni AG, Marinetti GV, Morrison WR, Natalia Vasilevna Gromova, Nikolai Zhelev, Novitskiy VV, Sikorski AF, Takakuwa Y, Vasil'yeva YEM, Vercaеmst L, Victor Vasilevich Revin, Vlasov AP   +25 more
core   +4 more sources

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

混合フォスファチジルコリン水溶液におけるひも状ミセル構造の形成 [PDF]

, 2015
東京海洋大学博士学位論文 平成26年度(2014) 応用生命科学 課程博士 甲第339号指導教員: 松川真吾全文公表年月日: 2014-12 ...
Fafaungwithayakul Natdanai
core   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Maternal and fetal metabolomic signatures in regard to birth outcome and gestational disease [PDF]

, 2018
Specific birth outcomes and gestational diabetes were shown to be associated with maternal and fetal metabolic alterations. Results of the current studies showed a higher number of associations between birth outcomes/gestational disease and fetal ...
Lu, YongPing
core   +1 more source