Results 31 to 40 of about 7,531 (229)

Lipidomic analysis of plasma samples from women with polycystic ovary syndrome [PDF]

open access: yes, 2015
Polycystic ovary syndrome (PCOS) is a common disorder affecting between 5 and 18 % of females of reproductive age and can be diagnosed based on a combination of clinical, ultrasound and biochemical features, none of which on its own is diagnostic.
A Dunaif   +40 more
core   +1 more source

Plasma lipid profiling of different types of hepatic fibrosis induced by carbon tetrachloride and lomustine in rats [PDF]

open access: yes, 2016
Supplementary tables. Table S1. Class, m/z, retention time, ion of detected and identified lipid molecules, and determined their fatty side chains. Table S2. Normalized levels of lipid molecules in individual samples. Table S3. Fold change and p-value of
Hiroshi Yamada   +5 more
core   +2 more sources

Serum lipidomic determinants of human diabetic neuropathy in type 2 diabetes

open access: yesAnnals of Clinical and Translational Neurology, 2022
Objective The serum lipidomic profile associated with neuropathy in type 2 diabetes is not well understood. Obesity and dyslipidemia are known neuropathy risk factors, suggesting lipid profiles early during type 2 diabetes may identify individuals who ...
Farsad Afshinnia   +11 more
doaj   +1 more source

Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response [PDF]

open access: yes, 2019
Insulin and insulin-like signaling regulates a broad spectrum of growth and metabolic responses to a variety of internal and environmental stimuli. For example, the inhibition of insulin-like signaling in C.
Baugh, Lauren   +5 more
core   +1 more source

Sets of coregulated serum lipids are associated with Alzheimer's disease pathophysiology [PDF]

open access: yes, 2019
Introduction: Comorbidity with metabolic diseases indicates that lipid metabolism plays a role in the etiology of Alzheimer's disease (AD). Comprehensive lipidomic analysis can provide new insights into the altered lipid metabolism in AD.
Arnold, Matthias   +10 more
core   +2 more sources

Circulating Pro- and Anti-Inflammatory Metabolites and Its Potential Role in Rheumatoid Arthritis Pathogenesis. [PDF]

open access: yes, 2020
Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that affects synovial joints, leading to inflammation, joint destruction, loss of function, and disability.
Coras, Roxana   +2 more
core   +2 more sources

Lysophosphatidylcholines and Chlorophyll-Derived Molecules from the Diatom Cylindrotheca closterium with Anti-Inflammatory Activity

open access: yesMarine Drugs, 2020
Microalgae have been shown to be excellent producers of lipids, pigments, carbohydrates, and a plethora of secondary metabolites with possible applications in the pharmacological, nutraceutical, and cosmeceutical sectors. Recently, various microalgal raw
Chiara Lauritano   +5 more
doaj   +1 more source

Age and gender-specific reference intervals for a panel of lysophosphatidylcholines estimated by tandem mass spectrometry in dried blood spots

open access: yesPractical Laboratory Medicine, 2023
Background and objectives: Very long-chain fatty acyl-lysophosphatidylcholines (VLCFA-LysoPCs) are measured in dried blood spots (DBS) for identifying X-linked adrenoleukodystrophy (X-ALD) and other inherited peroxisomal disorders.
Archana Natarajan, Rita Christopher
doaj   +1 more source

Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet [PDF]

open access: yes, 2019
Hutchinson-Gilford Progeria Syndrome (HGPS) is a devastating premature aging disease. Mouse models have been instrumental for understanding HGPS mechanisms and for testing therapies, which to date have had only marginal benefits in mice and patients ...
Albert, Carolyn J   +10 more
core   +2 more sources

Continuous fluorescence assay for lecithin:cholesterol acyltransferase using a water-soluble phosphatidylcholine.

open access: yesJournal of Lipid Research, 1992
A water-soluble fluorescent phosphatidylcholine, 1,2-bis[4-(1-pyreno-butanoyl]-sn-glycero-3-phosphocholine (DPybPC) has been used to develop a sensitive, continuous assay for pure lecithin:cholesterol acyltransferase (LCAT) in solution.
FS Bonelli, A Jonas
doaj   +1 more source

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