Results 181 to 190 of about 18,174 (203)

Lysophospholipid receptors in cell signaling

Biochemistry (Moscow), 2007
There is increasing evidence that different phospholipids are involved in regulation of various cell processes and cell-cell interactions. Lysophospholipids (lysophosphatidic acid, lysophosphatidylcholine) and a number of lysosphingolipids play particular roles in these regulations. Their effects are mediated by specific G-protein-coupled receptors.
T I, Torkhovskaya, O M, Ipatova, T S, Zakharova, M M, Kochetova, E M, Khalilov   +4 more
openaire   +2 more sources

Lysophospholipids and the cardiovascular system

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
The lysophospholipids sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) have varied effects on the cardiovascular system. S1P is necessary for normal vascular development and may play an important role in angiogenesis. These molecules may exert potentially detrimental effects.
openaire   +2 more sources

Stem cell regulation by lysophospholipids

Prostaglandins & Other Lipid Mediators, 2007
Lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) regulate a diverse range of mammalian cell processes, largely through engaging multiple G protein-coupled receptors specific for these lysophospholipids. LPA and S1P have been clearly identified to have widespread physiological and pathophysiological actions, controlling events within the ...
Pebay, A., Bonder, C., Pitson, S.
openaire   +3 more sources

Mechanisms of cardioprotection by lysophospholipids

Journal of Cellular Biochemistry, 2004
AbstractThe lysophospholipids sphingosine 1‐phosphate (S1P) and lysophosphosphatidic acid (LPA) reduce mortality in hypoxic cardiac myocytes. S1P is also cardioprotective in both mouse and rat models of cardiac ischemia/reperfusion (I/R) injury. Although these results are consistent with prior work in other cell types, it is not known what signaling ...
openaire   +2 more sources

Lysophospholipid Acylation in RBC.

Blood, 2006
AbstractThe formation, distribution and utilization of acyl-CoA plays a crucial role in plasma membrane phospholipid turnover in red blood cells (RBC). Upon de-acylation of glycero-phospholipids (PL) via the action of phospholipase, re-acylation of the lysophospholipids (LPL) requires activity of two enzymes of the Lands pathway.
Eric Soupene, Frans A. Kuypers
openaire   +1 more source

Lysophospholipids in the nervous system

Prostaglandins & Other Lipid Mediators, 2005
This piece offers perspectives on the emerging roles of lysophospholipids, which include lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P), for the biology and pathophysiology of the nervous system. It reflects opinions generated during a meeting sponsored by the National Institute on Drug Abuse (NIDA) entitled "Targeted Lipidomics ...
openaire   +2 more sources

Lysophospholipids as Mediators of Immunity

2006
Lysophospholipids (LPLs) are lipid-derived signaling molecules exemplified by lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Originally identified as serum-associated growth factors, these mediators now are known to signal through a family of diverse G protein-coupled receptors (GPCRs). Virtually all cells that participate in the immune
Debby A, Lin, Joshua A, Boyce
openaire   +2 more sources

Phospholipids | Lysophospholipid Receptors

2021
Sue C. Lee, Mélanie A. Dacheux, Gábor J. Tigyi   +2 more
openaire   +1 more source

Lysophospholipid‐Induced Cell Migration

Annals of the New York Academy of Sciences, 2000
T S, Panetti, D F, Mosher
openaire   +2 more sources

Lysophospholipid receptor nomenclature

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2002
openaire   +2 more sources