Results 61 to 70 of about 17,757 (160)

Biogenesis of the multifunctional lipid droplet: lipids, proteins, and sites [PDF]

open access: yes, 2014
Lipid droplets (LDs) are ubiquitous dynamic organelles that store and supply lipids in all eukaryotic and some prokaryotic cells for energy metabolism, membrane synthesis, and production of essential lipid-derived molecules.
Gross, Steven P.   +2 more
core   +1 more source

K2P channels and their protein partners. [PDF]

open access: yes, 2005
A decade since their discovery, the K2P channels are recognized as pathways dedicated to regulated background leakage of potassium ions that serve to control neuronal excitability. The recent identification of protein partners that directly interact with
Goldstein, Steve AN   +2 more
core   +1 more source

Sphingolipids as emerging mediators in retina degeneration [PDF]

open access: yes, 2019
The sphingolipids ceramide (Cer), sphingosine-1-phosphate (S1P), sphingosine (Sph), and ceramide-1-phosphate (C1P) are key signaling molecules that regulate major cellular functions.
Prado Spalm, Facundo Heber   +3 more
core   +1 more source

Lysophospholipid interactions with protein targets [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2008
Bioactive lysophospholipids include lysophosphatidic acid (LPA), sphingosine 1-phosphate (S1P), cyclic-phosphatidic acid (CPA) and alkyl glycerolphosphate (AGP). These lipid mediators stimulate a variety of responses that include cell survival, proliferation, migration, invasion, wound healing, and angiogenesis.
openaire   +2 more sources

Biocatalytic modification of food lipids: reactions and applications [PDF]

open access: yes, 2014
The acylglycerol structure exemplifies the major lipid building block and therefore is an interesting structure to modify. Such modification is driven by: (1) consumers who have become more concerned about the relationship between diet and wellness, and (
BAEZA JIMENEZ, RAMIRO   +5 more
core  

Microfluidics-based liquid chromatography/mass spectrometry multiple reaction monitoring approach for the relative quantification of Burkholderia cenocepacia secreted virulence factors [PDF]

open access: yes, 2018
Rationale: Burkholderia cenocepacia is an opportunistic pathogen that is commonly isolated from patients with cystic fibrosis (CF). Quorum sensing has been suggested to play a role in the activity of type II and type VI secretion systems and the release ...
Daled, Simon   +6 more
core   +2 more sources

Cold comfort pharm [PDF]

open access: yes, 2007
Cooling of the skin has long been thought to be beneficial in pain states but intense cold is clearly noxious. Does cooling lead to pain or gain? Rapid progress in this controversy has been made since the discovery of specific ion channels of the ...
Allchorne, A   +5 more
core   +1 more source

Experimental and computational studies on lipoprotein lipolysis at acidic pH [PDF]

open access: yes, 2010
Atherosclerosis is a disease of the arteries; its characteristic features include chronic inflammation, extra- and intracellular lipid accumulation, extracellular matrix remodeling, and an increase in extracellular matrix volume.
Lähdesmäki, Katariina
core  

Chemical Impacts of the Microbiome Across Scales Reveal Novel Conjugated Bile Acids [PDF]

open access: yes, 2019
A mosaic of cross-phyla chemical interactions occurs between all metazoans and their microbiomes. In humans, the gut harbors the heaviest microbial load, but many organs, particularly those with a mucosal surface, associate with highly adapted and ...
Mazmanian, Sarkis   +2 more
core  

Lysophospholipids in the limelight [PDF]

open access: yesThe Journal of Cell Biology, 2002
Lysophosphatidic acid (LPA) is a serum phospholipid that evokes growth factor–like responses in many cell types through the activation of its G protein–coupled receptors. Although much is known about LPA signaling, it has remained unclear where and how bioactive LPA is produced. Umezu-Goto et al.
openaire   +1 more source

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