Results 71 to 80 of about 13,819 (214)
MetabolitesChronic obstructive pulmonary disease (COPD) is a heterogeneous lung condition characterized by persistent respiratory symptoms and airflow limitation. While there are some available treatment options, the effectiveness of treatment varies depending on ...
Qiqiang Zhou +3 more
doaj +1 more source
Cancer Science, EarlyView.Immune surveillance of residual leukemic stem cells after tyrosine kinase inhibitor discontinuation involves coordinated NK‐cell, CTL, Treg, pDC, and neutrophil activity that predicts treatment‐free remission, while exhausted CTLs and Treg expansion predict relapse in chronic myeloid leukemia.
Hiroshi Ureshino, Shinya Kimura
wiley +1 more source
Effects of Lysophospholipids on Tumor Microenvironment [PDF]
Cancer Microenvironment, 2011 The effects of lysophospholipids (LPLs) on cancer microenvironment is a vast and growing field. These lipids are secreted physiologically by various cell types. They play highly important roles in the development, activation and regulation of the immune system. They are also secreted by cancerous cells and there is a strong association between LPLs and
Johannes, Rolin, Azzam A, Maghazachi
openaire +2 more sources
Studies of lysophospholipids related to the hamster sperm acrosome reaction in vitro [PDF]
, 1993 Phospholipase A2 and lysophospholipids have been implicated in the mammalian sperm acrosome reaction. In this study we further investigated the role of this enzyme and lysophospholipids on the acrosome reaction of hamster spermatozoa.
Llanos Silva, Miguel +2 more
core +1 more source
CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems
The FEBS Journal, EarlyView.Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén +11 more
wiley +1 more source
Function and Modulation of Sphingosine-1-Phosphate Receptors in the Central Nervous System
ReceptorsSphingolipids, first discovered in 1874 by Johann Thudicum, are among the eight recognized classes of lipids and are present in essentially all plants, animals, and fungi, as well as some viruses and prokaryotes. In mammals, sphingolipids are enriched in
Elizabeth Gulliksen +7 more
doaj +1 more source
Obesity Reviews, EarlyView.ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid +22 more
wiley +1 more source
Frontiers in Veterinary ScienceObjectiveThis study was designed to evaluate the effects of supplementing dairy cow diets with lysophosphatidylcholine (LPL) on production performance, serum biochemical parameters, and rumen fermentation profiles.MethodsA total of 20 Holstein dairy cows
Ruoran Tao +10 more
doaj +1 more source
Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat
Plant Biotechnology Journal, EarlyView.ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv +11 more
wiley +1 more source
, 2011 Research in the author's laboratory is supported in part by a Wellcome Trust Senior Research Fellowship (067441), and Wellcome Trust project grants (086658 and 093228) and a Wellcome Trust Prize Studentship (G.S.R).Phospholipase A1 (PLA1) is an enzyme ...
Smith, Terry K. +3 more
core +1 more source